Program Officer or Assistant Director, Aging & Alzheimer’s Prevention Program


Alzheimer's Drug Discovery Foundation


New York, New York


Please email cover letter and resume, including salary requirements, to: with “Aging and Alzheimer’s Disease Prevention” in the subject line. Resumes without cover letters will not be considered. Due to the high volume of applications, only applicants who best match the position's needs will be contacted.  No phone calls.


The Aging and Alzheimer’s Prevention program at the Alzheimer’s Drug Discovery Foundation (ADDF) works towards two goals to advance potential therapies to safely promote healthy aging and prevent Alzheimer’s, related dementias, and cognitive aging.

  1. Identify and evaluate the available evidence for safety and efficacy of promising prevention therapies or combinations of therapies.
  2. Develop new evidence through funding and programs targeted to unmet needs in prevention research. An emerging priority is the use of bioinformatics, epidemiological data, and electronic health records to gain real-world data insights into possible prevention therapies.

Primary Responsibilities:

  • Survey diverse sources of information such as the scientific literature and social media to identify promising or controversial therapies to be evaluated.
  • Identify and critically evaluate the scientific literature for safety and efficacy of promising prevention therapies ranging from repurposed drugs, drugs in development, natural products and supplements, non-pharmaceutical therapies, and the reduction of exposure to potential harms. Analyses should consider possible combination therapies and whether therapies should be tailored to individuals based on characteristics like risk factors, genetics, and biomarkers.
  • Critically evaluate and communicate how risk factors, lifestyle changes, and biomarkers may indicate a risk of cognitive decline.
  • Manage day-to-day development of, a product of the ADDF that provides consumer-friendly reports on the scientific evidence that potential prevention therapies are either safe or effective.
  • Develop opportunities to advance prevention therapeutics research using epidemiology and real-world data. Possible approaches include provide funding to academic or biotech investigators for specific (joint) projects, directly supervising analysts, and providing thought leadership through advisory panels and position papers with key opinion leaders.
  • Promote and expand programs that capitalize on the Cohorts for Alzheimer’s Prevention Action (CAPA) Consortium, which allows collaborative analyses on dementia prevention across multiple cohorts.
  • Promote and expand comparative effectiveness research.
  • Manage a portfolio of grant applications for ADDF funding by proactively soliciting applications, assisting in the review process, communicating reviewer feedback to applicants, and monitoring the progress of successful funded applicants.
  • Represent ADDF at scientific conferences to identify promising therapies and maintain up-to-date knowledge of research in aging, Alzheimer’s, and related dementias.
  • Meet with donors and represent ADDF at fundraising and public events.
  • Work with the ADDF science team as needed on programmatic efforts like organizing conference agendas and writing peer-reviewed scientific articles.

The successful candidate will report directly to the director of Aging & Alzheimer’s Prevention and will be overseen by ADDF’s Founding Executive Director and Chief Science Officer. The position is located in midtown Manhattan, New York. Salary will be commensurate with experience.


Applicants should have a Ph.D. and/or M.D. in neuroscience/neurology, pharmacology/pharmacy, epidemiology, or related fields with some understanding of neurodegeneration biology. Additional expertise in areas such as clinical trial design, evidence-based medicine, systems biology, big data analysis, and/or natural products is a plus. The ideal candidate will have strong scientific credentials with an aptitude for rapidly assimilating new fields and critically evaluating scientific research. She or he will enjoy working both collaboratively and independently, and have strong analytic abilities and outstanding communication and writing skills. Experience communicating scientific evidence to the general public will be a strong plus.