Postdoctoral Researcher in the Genomics and Neuropathology of Neurodegenerative Disease
Posted 31 Oct 2017
Icahn School of Medicine at Mount Sinai
New York, New York
Please send a C.V. and the names of at least two references to firstname.lastname@example.org.
The Ronald M. Loeb Center for Alzheimer’s Disease, directed by Alison Goate, at the Icahn School of Medicine at Mount Sinai is seeking a passionate individual to investigate the neuropathology and genetics of neurodegenerative tauopathies. The center uses advanced genomic and computational approaches to identify novel drivers of disease pathogenesis.
This NIH-funded project focuses on understanding the overlap between Alzheimer's disease, Parkinson’s disease, and tauopathies. The candidate will join a highly productive team that includes geneticists, computational biologists, cell biologists, and physician-scientists. The successful candidate will play an active role in deploying next-generation sequencing data (DNA/RNA) and correlating results with novel endophenotypes to elucidate pathogenic drivers and etiologies.
- To assist in the design of genomics experiments.
- To analyze publicly available and novel genomic data sets (e.g., long-read DNA and RNA), including quality control, variant identification, annotation, and association with clinical/neuropathological outcomes using existing computational resources in R and other programs.
- To work toward development of independent scientific ideas and postdoctoral-appropriate grants (e.g., K award, R03), with a long-term goal of independent investigator status.
The applicant must have:
- Experience with genetics and a recent doctoral degree (e.g., Ph.D.) in computational biology, computer science, genetics, epidemiology, biostatistics, bioinformatics, or related field. Alternatively, an M.D. with additional relevant computational experience.
- Expertise in R and R/Bioconductor and a scripting language (e.g., perl/python) in a Unix environment.
- An interest in working with a diverse group of scientists to advance understanding of neurodegenerative diseases through a synergy of wet and dry lab approaches.