Postdoctoral Researcher Climate Change and Health (m/w/d)


German Center for Neurodegenerative Diseases (DZNE)


Bonn, Germany

Principal Investigator

Antonio Schmandke



Climate change majorly affects many aspects of life. To help develop tenable solutions for global warming and to evaluate the impact of climate change on health, the Helmholtz Association has established a large-scale cross-disciplinary research program, “Helmholtz-Initiative Climate Adaptation and Mitigation” (HI-CAM). As part of this initiative, DZNE will collaborate with other health-related research institutes across Germany on analyzing the impact of extreme weather on cardiovascular, metabolic, and cognitive functions and mental health. In that context, the Schmandke lab is searching for a postdoctoral researcher climate change and health (f/m/d).

The aim of this project is to investigate the impact of ambient temperature and humidity exposure on health. The research will use available geocoded daily temperature and humidity exposure data and link those to individual participant data from the Rhineland Study, a deeply phenotyped population-based cohort in Bonn, Germany. The study will include more than 20,000 people aged 30 years and older, run for decades, and emphasize brain-related outcomes.


Using extensive existing data on physiologic parameters (including metabolomic data; lipidomic data; serum virus antibody titers; microbiome data; cytokine profiles), the researcher will derive biomarkers, physiological patterns, and mechanistic pathways that are influenced by ambient temperatures and humidity. Next, he or she will evaluate the potential health impact of those biomarker profiles and pathways by investigating their relationship with health phenotypes, in particular structural and functional markers of brain health (brain MR data, cognition data). The researcher will analyze the data and prepare manuscripts for publication in peer-reviewed journals and maintain contact with our external collaborators. In addition, he or she will be expected to engage in and actively contribute to overall activities related to the conduct and further general development of the Rhineland Study.

The position offers interesting and challenging work on the forefront of health research in a highly interdisciplinary and international team. The common language at work is English.

The DZNE actively encourages and supports employees’ personal development and growth.

The fulltime position is initially limited to two years with the possibility of extension. Employment, payment and social benefits are determined by the Public Sector Collective Agreement (TVöD-Bund).


Candidates preferably have a Ph.D. in epidemiology, medicine, applied statistics, computational biology, or other relevant discipline, and experience in the field of high-dimensional data analysis. Demonstrated interest in quantitative research, strong analytical skills, ability for independent and critical thinking, and excellent communication and writing skills in the English language are prerequisites. Working experience in epidemiological research or large-scale observational studies is desirable. A track record of publishing high quality scientific papers is a sine qua non.