Jobs

Postdoctoral Research Fellow

Employer

Brigham and Women's Hospital; Harvard Medical School

Location

Boston, Massachusetts

Principal Investigator

Cynthia Lemere

Contact

clemere@bwh.harvard.edu

Description

The Lemere Lab at Brigham and Women’s Hospital and Harvard Medical School is seeking a highly motivated postdoctoral fellow to investigate the sex- and ApoE-specific late central nervous system (CNS) effects of simulated deep-space cosmic radiation on Alzheimer’s disease-like transgenic and wild-type mice. The three-year postdoctoral position is available immediately and is supported by a NASA grant. Radiation effects on mouse behaviors, Aβ pathologies, neuroinflammation, synaptic function and integrity, neuron apoptosis, brain structure, and cardiovascular outcomes (including longitudinal MRI scans of brain and heart) will be determined.

Requirements

Successful candidates will have an excellent track record and be highly motivated scientists who can carry out independent experiments and work well with a team. The successful candidate will play a critical role in contributing to the design and execution of the overall aims of the project.

A qualified applicant should have:

  • A Ph.D. and laboratory experience in neuroscience, molecular biology, and/or biochemistry.
  • Extensive experience working with mice; mouse behavioral testing is helpful.
  • Proficiency with standard molecular and cell-biology techniques, including ELISA, Western blot, RT-PCR, flow cytometry, and high-resolution confocal microscopy.
  • Strong skills in organization, data handling and statistical analysis.
  •  Background in Alzheimer’s disease is helpful but not necessary.
  • Proficiency in English with excellent oral written, and interpersonal communication skills.
  • Available to start by the end of June 2019 or earlier.