Postdoctoral Research Associate, Bioinformatics / Statistical Genetics


Washington University


St. Louis, Missouri

Principal Investigator

Carlos Cruchaga


Washington University is seeking applicant for a postdoc position to work in the lab of Drs. Cruchaga and Harari at the School of Medicine. The goal of their research is to use genomic approaches to understand the biology of Alzheimer’s disease, Parkinson's disease, and other neurodegenerative diseases. The labs have pioneered the use of biomarker levels for Alzheimer's and Parkinson's as endophenotypes for genetic studies. By using this approach, the lab has identified six novel loci associated with Alzheimer's risk, progression, and onset.

The lab is looking for a postdoc with expertise in GWAS, exome-chip, WES and WGS and Mendelian randomization to work in a project focused on the identification of novel biomarkers for Alzheimer’s and Parkinson's disease using genomic approaches using a very large and well characterized-data set with proteomic, genetics, and transcriptomic data available.

She/he will join a team of nine computational and statistical researchers working in bioinformatics, statistical genomics, and genetics working in the laboratory of Drs. Cruchaga and Harari, which comprises more than 20 people dedicated to understanding the architecture of neurodegenerative diseases.

This position is offered initially one to two years with a maximum of five years. There is flexibility over starting dates, but successful applicants are welcome to take up post starting September 1, 2018. Salary and benefits will follow the NIH pay scale.


Candidates must hold a Ph.D. in statistics, bioinformatics, computational biology, biostatistics, statistical genetics, medical statistics, mathematics, or a similar subject. Candidates should have a strong background in GWAS (PLINK and SKAT-O), and second-generation sequencing. A working knowledge of UNIX, Perl/Python, and R are also required.