Jobs

Postdoctoral Research Associate

Employer

University of Bath

Location

Bath, England, U.K.

Principal Investigator

Rob Williams

Contact

For more information and to apply please see https://www.bath.ac.uk/jobs/Vacancy.aspx?ref=CC6789. For more information or informal enquiries please contact Dr. Rob Williams: r.j.williams@bath.ac.uk.

Description

Dr Rob William’s lab at the University of Bath, UK, is looking for an enthusiastic and highly motivated individual who is interested in the molecular mechanisms of neurodegeneration and specifically in exploring the neuroprotective potential of polyphenol metabolites in Alzheimer’s Disease.

The position will involve testing novel metabolites against Aβ and tau toxicity in different cell platforms including primary neurons and microglia, human stem cells, and neuroblastoma cell lines. The work will make use of novel gene reporters, high content and live cell imaging, proteomics and RNA sequencing. Biophysical aspects will be undertaken in collaboration with Professor Jody Mason’s group. This is an exciting project in an important therapeutic area, for which training and support will be given throughout, including regular meetings between team members.

Requirements

This 30-month Alzheimer’s Society-funded postdoctoral position is available from September 2, 2019, and applicants must be highly motivated and hold a Ph.D. in a relevant science subject such as biochemistry, neuroscience, or molecular biology. Candidates should have experience in molecular cellular neuroscience, mammalian cell culture, cloning and cell imaging. Knowledge of protein biochemistry and/or the innate immune system would be an advantage.