Jobs

Postdoctoral position – Innate Immunity and Neurodegeneration

Employer

Icahn School of Medicine at Mount Sinai

Principal Investigator

Towfique Raj

Contact

towfique.raj@mssm.edu

Description

The Raj Lab at the Icahn School of Medicine at Mount Sinai is seeking a passionate postdoctoral fellow to investigate the role of innate immune cells in Parksinson’s disease. The postdoctoral position will support recently funded research project to explore the role of immune cells including peripheral monocytes/macrophages and CNS microglia in the neurodegenerative process in Parkinson’s disease. The goal of the project is to investigate the mechanistic role of Parkinson’s disease susceptibility genes. The candidate will use innovative functional genomics approaches to perform ex-vivo analysis of peripheral monocytes, and evaluate immune and disease biomarkers in different biological fluids. In addition, in vitro cellular characterization using cultures will be also included in the project. The studies will be complementary to Alzheimer’s disease research in parallel by other members of the team. Close interaction and constant scientific exchange will be essential for the advance of the project. The candidate will have access to human biological, clinical, and genetics data from Parkinson’s disease patients recruited from as part of the New York Movement Disorder Study.

Successful candidates will have an excellent track record and will be highly motivated self-driven candidate. The successful candidate will play a critical role in contributing to the design and execution of the overall aims of the project. Experience with experimental techniques for myeloid phagocytosis and autophagy will be a plus. The position is funded by grants from the Michael J Fox Foundation and the National Institutes of Health.

Requirements

  • Ph.D. in neuroimmunology, immunology, molecular and cellular biology, neuroscience, or an equivalent discipline.
  • Proficiency with standard molecular and cell biology techniques. • Experience with cell sorting, FACS / flow cytometry techniques.
  • Effective oral, written, and interpersonal communication skills. • Ability to handle multiple tasks and projects simultaneously.
  • Effective organizational and prioritization skills. • Ability to work and communicate effectively in an interdisciplinary work environment.
  • An interest in working with a diverse group of scientists to advance understanding of neurodegenerative diseases through a synergy of wet and dry lab approaches.