Jobs

Postdoctoral Position

Employer

Thomas Jefferson University

Location

Philadelphia, Pennsylvania

Principal Investigator

Hristelina Ilieva

Contact

Interested candidates, please send a CV describing prior experience and technical skills as well as a letter of interest to Hristelina Ilieva, hristelina.ilieva@jefferson.edu.

Description

The Weinberg ALS Center is looking for a postdoctoral fellow to join its translational research program under the supervision of Hristelina Ilieva. This program focuses on cell, molecular, and biochemical work using bio-fluids (urine and blood), skin biopsy samples, and, ultimately, iPSC-motor neurons derived from patients with amyotrophic lateral sclerosis (ALS) and fronto-temporal dementia (FTD). The goal is to use these samples as templates to (a) identify disease biomarkers and (b) in cases of genetically-linked ALS, elucidate details the pathogenic mechanism(s) related to the genetic abnormality. The postdoc will use several approaches, including neuronal cell culture, molecular biology, genetics, biochemistry, advanced microscopy, and analysis of human tissue samples. Experience with stem cells is a plus but not obligatory. Projects led by the successful candidate will develop taking advantage of the postdoc's existing expertise while allowing growth and development.

The laboratory and the Weinberg ALS Center offer a dynamic team of clinicians and scientists with a broad range of expertise working collaboratively with the common goal of making an impact on the lives of ALS/FTD patients. The postdoc will work both independently and cooperatively and will have access to several superb research facilities at Jefferson and within the Weinberg ALS Center. The postdoc will benefit from career-development opportunities, a dedicated support network within the Weinberg Center and across campus at Jefferson, with the goal to forge new research directions, make seminal discoveries, and publish high-profile findings.

Salary is competitive and commensurate with experience. A postdoctoral benefits package is also available through Jefferson University. The position is available immediately.

Requirements

A Ph.D. in a relevant area of neuroscience research and/or advanced techniques in biochemistry, molecular biology, and cell biology; a deep understanding of molecular mechanisms of neurodegeneration; and a strong desire to make important scientific discoveries, to build new research directions, and to apply one's expertise and develop new skills to advance the lab's research goals.

A record of high-profile first-author publications together with a record of success in competitive funding schemes, and prizes and awards for research, will make candidates particularly competitive for this position. We value diversity and inclusion, and actively encourage applications from those who bring diversity to the university.