Jobs

Postdoctoral Fellows - Molecular Mechanisms of Parkinson’s Disease

Employer

Mayo Clinic

Location

Jacksonville, Florida

Principal Investigator

Wolfdieter Springer

Contact

Interested candidates should send their curriculum vitae, a statement of research experience/interests, and contact information for two or three references to: Wolfdieter Springer, Associate Professor, Department of Neuroscience, Mayo Clinic, email: Springer.Wolfdieter@mayo.edu.

For more information see link: https://www.mayo.edu/research/labs/translational-cell-biology-parkinsons-disease/overview.

Description

Postdoctoral positions are open in Wolfdieter Springer’s laboratory at Mayo Clinic in Jacksonville, Florida. The NIH-funded laboratory is focused on mitochondrial quality control and its role in neurodegenerative diseases. The lab infrastructure includes super-resolution and high-content imaging, digital pathology, culture, and genome editing of human neuronal cell models such as iPSCs, biochemical studies, drug development, and multi-omic analyses.

Active projects in the lab include mechanisms of PINK1-PRKN-dependent mitophagy, phosphorylated ubiquitin as a biomarker for mitophagy in human brain and fluid samples, disease signature of mitochondrial quality control failure, genome-engineered models for activated mitophagy, drug discovery for mitophagy activators, and genome-wide analysis of mitophagy modulators.

Requirements

Successful candidates must have a Ph.D. degree along with a strong background in cell biology, protein and lipid biochemistry, neuroscience or relevant field, must be highly motivated, and able to work collaboratively. Fluent English, a track record of strong publications, and a cooperative attitude are a must for this position. Successful applicants will benefit from an outstanding research and training environment at Mayo Clinic with a competitive salary and benefit package, commensurate with experience.