Jobs

Postdoctoral Fellow in ALS/FTD Research

Employer

Queensland Brain Institute, University of Queensland

Location

Brisbane, Australia

Principal Investigator

Adam Walker

Contact

For more information and applications please visit https://jobs.uq.edu.au/caw/en/job/504539/postdoctoral-research-fellow. Applications should include a detailed CV and address the selection criteria. Applications close July 10, 2018, with start date to be negotiated (expected ~August, 2018).

Description

This position involves conducting and analyzing experiments to understand molecular mechanisms and identify potential treatments for amyotrophic lateral sclerosis/motor neuron disease and frontotemporal dementia, with a focus on cellular stress responses, protein aggregation, and novel pathogenic biochemical pathways. The postdoctoral fellow will use techniques including biochemistry, primary cell culture, immunohistochemistry, advanced molecular biology and microscopy, lentiviruses and AAVs, analysis of human tissues, and transgenic mouse stereotactic surgery, behavioral analysis and preclinical testing, to identify and understand new potential therapeutic targets.

Neurodegeneration Pathobiology Laboratory

The lab (led by Adam Walker) focuses on molecular, cellular and mouse model studies of the causes and potential treatments for motor neuron disease (MND) and frontotemporal dementia. For more information please visit qbi.uq.edu.au/walkergroup and walkerneurolab.org.

Organisational Environment

The Queensland Brain Institute works to understand the development, organization, and function of the brain, aiming to understand the neural circuits in the brain, how their function results in behavioural outcomes, and how dysfunction of these circuits leads to disorders such as dementia, Parkinson’s disease, and schizophrenia. The work focuses on 1) developing novel therapeutic approaches to treat disorders of neural function and (2) using understanding of brain function to improve learning in classrooms and in the workplace. Established in 2003, QBI (www.qbi.uq.edu.au) is housed on the St Lucia campus of The University of Queensland (UQ).

Remuneration

This is a full-time, fixed term appointment at Academic Research Level A (initially 12 months, with the possibility of extension). The remuneration package will be in the range of AUD$81,545-$87,535 p.a., plus employer superannuation contributions of up to 17 percent (total package will be in the range of AUD$95,407-$102,416 p.a.).

Requirements

Applicants must have a Ph.D. in a relevant area of research, such as neuroscience or cell biology. You will have demonstrated expertise in techniques involving biochemistry, molecular biology, cell biology, or mouse models of neurological disease (including stereotactic surgery in neonatal and adult mice). Experience in the use of cutting-edge techniques including CRISPR and in vivo AAVs, and a deep understanding of molecular mechanisms of neurodegeneration with particular focus on MND and FTD will be an advantage.

You will have a strong desire to make important scientific discoveries, to build new research directions and to apply your expertise and develop new skills to advance our research goals. A record of high-profile first-author publications in neuroscience or cell biology together with a record of success in competitive funding schemes, and prizes and awards for research is ideal.

The University of Queensland values diversity and inclusion and actively encourages applications from those who bring diversity to the University.

Please refer to the University’s Diversity and Inclusion webpage for further information and points of contact for additional support.

Accessibility requirements and/or adjustments can be directed to the contact person listed in the job advertisement.