Posted 24 May 2018
NYU Langone Health; Center of Cognitive Neurology; Conformational Disorders
New York, New York
Qualified applicants should provide a cover letter outlining research experience and interests, a curriculum vitae, and the names and address of three references addressed to Dr. Wisniewski.
The Conformational Disorders Laboratory has a position available for one postdoctoral fellow.
This laboratory is within the Center of Cognitive Neurology, in the Department of Neurology at the NYU Langone Medical Center. The Wisniewski lab has worked on elucidating the pathogenesis of Alzheimer's disease and prion diseases, with an aim to develop possible therapeutic strategies for many years. This work has led to more than 300 peer-reviewed publications and 23 issued U.S. patents, and the lab has been continuously funded by NIH for more 25yrs.
The lab is looking for candidates with a background in neuropathological techniques, proteomics and immunology.
This postdoctoral position is available for a motivated, enthusiastic Ph.D. graduate who has a broad background in the areas described. Specifically, the fellow will investigate the heterogeneity of the proteome in Alzheimer’s disease and Down’s syndrome.
The Wisniewski lab has recently developed an unbiased proteomic methodology that produces robust data utilizing archival formalin, fixed paraffin embedded human tissue, and it has used this method perform the most extensive proteomic analysis of amyloid plaques, as well as to characterize the amyloid proteome of a distinct subtype of AD: rapidly progressive AD. The project will involve use of these localized proteomic techniques in rapidly progressive AD, versus more typical sporadic AD, as well as in Down’s syndrome brain tissue at different stages of disease.
Non-U.S. citizens are eligible to apply.
The effective date of appointment would be June 1, 2018, or later.
NYU is an equal opportunity, affirmative action employer. Women and minority candidates are strongly encouraged to apply.
Description of a successful candidate:
- A self-motivated and driven individual who is able to exhibit exceptional research productivity and take responsibility for independent management of the project.
- A detail-oriented researcher who thinks critically to effectively design experiments and solve complex research problems.
- The ability to work in a team environment, and interact with students who will need instruction.
- A collaborative, hands-on researcher who proactively shares knowledge and expertise with lab members.
- Excellent written and oral communication skills, with the ability to prepare manuscripts and assist with grant applications.
- A Ph.D. with experience and recent publications in the field of Alzheimer’s disease and/or other neurodegenerative diseases.
- Knowledge of neuropathological techniques, work with human tissue, and computational skills with large datasets are required. In addition, a good working knowledge of general neuroscience and various proteomic techniques is preferred.
- Experience with scientific writing and publication.
- Must provide the names of three individuals who can provide recommendations and present a scientific seminar describing his or her previous research.