Posted 28 Sep 2021
New Haven, Connecticut
Yale is seeking a talented, highly motivated researcher to join the laboratory of Professor Jaime Grutzendler in the departments of neurology/neuroscience and the Wu Tsai Institute. The lab's overall goal is to uncover rules that govern the complex interactions between all brain-cell types in their unperturbed in vivo microenvironment and to determine how these dynamic cell-cell interactions are disrupted in a variety of disease states. The lab utilizes high-resolution cellular imaging in vivo and fixed tissues of single cells and small clusters of interacting cells combined with novel optical sensors of cellular physiology, optogenetics, chemogenetics, genome-editing techniques, and methods its researchers develop for improving the ability to visualize and manipulate individual cells in their native environment. The approach tends to be hypothesis-generating and can take the lab in different directions such that projects in the lab can have a neuronal, glial, or vascular focus. Finally, discoveries derived from these investigative strategies inspire the translational neuroscience program aimed at developing novel therapies and imaging strategies for neurodegenerative conditions.
Highly motivated candidates with a recent Ph.D. or M.D./Ph.D. degree in the fields of neuroscience, cell biology, molecular biology, biochemistry, pharmacology, or biomedical engineering are encouraged to apply. Demonstrated record of achievements, publications, and a strong command of written and spoken English.