Jobs

Postdoc Position on Studying Neurodegenerative Disease

Employer

Case Western Reserve University

Location

Cleveland, Ohio

Principal Investigator

Xin Qi

Contact

Interested individuals should send a cover letter, CV, and the names/phone numbers of three people who could provide letters of reference by email to xxq38@case.edu. Please visit the lab website at https://xinqilab.com/ for additional information.

Description

A postdoc position is immediately available in the laboratory of Dr. Xin Qi in the department of Physiology & Biophysics at Case Western Reserve University School of Medicine.

The lab focuses on mitochondrial pathology in neurodegenerative diseases. It uses a combination of in vitro cell culture, in vivo transgenic animal models, and patient-derived neurons to study the mechanisms by which mitochondrial impairment contributes to neurodegeneration. Another research focus is the development of therapeutics that enhance mitochondrial function, for the treatment of human diseases. The lab has been using the rationally designed peptide inhibitors of protein-protein interactions and high-throughput screening to identify mitochondrial functional enhancers as therapeutics.

The successful applicant will participate in NIH-funded projects on elucidating molecular basis of mitochondrial quality control with novel transgenic mouse models of neurodegenerative diseases. The qualified candidate will also be part of the drug discovery project for neurodegenerative diseases. 

Requirements

The applicant must have a Ph.D. and/or M.D. degree in neuroscience, molecular biology, cell biology, pharmacology, or related field. Candidates with experience in neurodegenerative diseases and transgenic mouse models are highly desired.