Postdoc position to study spatiotemporal relationships between gliosis, synaptic loss, and atrophy in human neurodegenerative diseases


University of California, San Francisco


San Francisco , California

Principal Investigator

Lea T. Grinberg


Applications will be reviewed on an ongoing basis until the position is filled. Please direct inquiries to Dr. Lea T. Grinberg by sending a letter of interest, CV, and at least three references to


UCSF is seeking a postdoctoral fellow who will be integral in a multidisciplinary effort for developing novel PET markers for synapses in humans brains for use in neurodegenerative disease.

Working with neuropathologists, neurologists, and neuroscientists, the postdoc will help understand the spatiotemporal relationship between gliosis, synapse loss, and atrophy in the pathophysiology of neurodegenerative disorders to validate candidate PET tracer in postmortem human tissue, using immunohistochemistry, quantitative neuropathology, and imaging analysis.

This position presents an outstanding training experience for a candidate who wishes to grow a career in the neurodegenerative disease field. Successful candidates should be scientifically motivated self-starters and comfortable working in a highly productive academic environment.

The candidate will work with a multidisciplinary team as part of an academia-pharma alliance that brings together world-class researchers and clinicians to speed up new treatments for neurological and psychiatric diseases. The primary appointment will be at the Grinberg Lab, Memory and Aging Center at UCSF.

UC San Francisco seeks candidates whose experience, teaching, research, or community service that has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status.


Preferred Qualifications:

  • Ph.D. in neurosciences, biology, molecular biology, physiology, or related fields, and have first-author publications in peer-reviewed journals.
  • Career interest in neurodegenerative diseases.
  • Experience with microscopy.
  • Experience with quantitative pathology.
  • Experience with microscopic imaging analysis.
  • Prior training in mammalian anatomy is a plus.
  • The candidates should be creative thinkers, organized, demonstrate excellent communication skills and ability to work collaboratively.