University College London, UK Dementia Research Institute


London, England

Principal Investigator

Marc Aurel Busche



The Busche lab (, at the U.K. Dementia Research Institute at UCL, is looking for a highly self-motivated individual to combine in vivo electrophysiology and imaging with behavioral studies in models of Alzheimer’s disease and related disorders. The planned research projects are targeted to elucidate the cellular mechanisms that underlie memory and other cognitive impairments in these disorders. The post holder will perform in vivo electrophysiology and/or multiphoton imaging in behaving mice, process and analyse the electrophysiological and imaging datasets, evaluate and communicate results, publish results in peer-reviewed journals, and present findings at scientific conferences.

The post is available immediately and is funded by the UK DRI @ UCL for a period of three years in the first instance.

Please apply at


The successful candidate will hold a Ph.D. or equivalent in neuroscience or a neuroscience-related or quantitative discipline (e.g. physics, applied mathematics, engineering, bioinformatics). S/he will have a strong statistical analysis background and track record of writing and publishing high-quality scientific articles. Experience in systems neuroscience and/or computational neuroscience involving in vivo electrophysiology, calcium imaging, and behavioural analyses is essential, as is strong programming and coding ability (MATLAB, Python, other), especially with regard to analyzing electrophysiological and imaging data. Candidates must have excellent interpersonal skills and cooperation within a multidisciplinary team.

Experience with anatomical mapping, optogenetics or fiber-photometry and biochemistry/molecular biology techniques including immunohistochemistry and western blotting is desirable.