Experienced Researcher (f/m/d) in Population Neuroimaging


German Center for Neurodegenerative Diseases (DZNE)


Bonn, Germany

Principal Investigator

Antonio Schmandke


Please find the official job advertisement under the following link:


The DZNE studies determinants and biomarkers of normal and pathological mental and physical health function over the adult life course, with a special emphasis on neurodegenerative diseases and ageing. The research is led by Prof. Monique M.B. Breteler and is primarily based on data from the Rhineland Study. This prospective population-based cohort study will include more than 20,000 people aged 30 years and older, run for decades, and emphasize brain-related outcomes. Core data collection includes extensive structural and functional brain imaging, cognitive and behavioral assessments, cardiovascular investigations, sensory systems assessments, questions on medical history, medication intake, lifestyle, nutrition and mental health, collection of biomaterials, and wide-ranging omics analyses.

Brain imaging is an essential part of our data collection and prominent in research. All eligible participants of the Rhineland Study undergo an advanced 1h MRI protocol at each examination. The core protocol acquires state-of-the-art anatomical, functional, and structural connectivity data in the whole brain with high isotropic resolution. A “free protocol” with varying sequences addresses additional research questions in subgroups. DZNE already has brain imaging data from thousands of participants, and data collection is ongoing. The Schmandke lab works with an interdisciplinary team of image analyzers, IT experts, and other data scientists to build the relevant image analysis pipelines and perform further feature extraction and data analysis.


The researcher is expected to take a leading role in the further development of research efforts in this area. Responsibilities include but are not limited to: supervision of data acquisition and processing; analysis of data and preparation of manuscripts for publication in peer-reviewed journals; supervision of graduate students; maintaining contact with internal and external academic partners; preparation of grant applications, development of own research focus. Additionally, he or she is expected to actively contribute to the general conduct and further development of the Rhineland Study.

The position offers an interesting and challenging work in a highly interdisciplinary and international scientific environments with English as a common language at work is English. DZNE actively encourages and supports employees’ personal development and growth. The position is initially limited to two years, extension possible. Employment, payment and social benefits are determined by the Public Sector Collective Agreement (TVöD-Bund).

The professional qualification of early career researchers is of great importance for DZNE. Besides special offers for career development and support, the DZNE also provides researchers career opportunities in form of junior research groups or internal career paths to obtain scientific independence.


The DZNE is looking for a highly talented, motivated, enthusiastic, and ambitious researcher with good social skills. A Ph.D. in medicine (radiology), physics, epidemiology, applied statistics, cognitive neuroscience, or other relevant discipline is required. Experience with large-scale brain imaging data and very good epidemiological knowledge are prerequisites, as are a demonstrated interest in quantitative research, the possession of strong data analytical skills, leadership capabilities, and the ability for independent and critical thinking. A track record of publishing high quality scientific papers is a sine qua non.