Antibody

ZO-1

Clonality: polyclonal
Host: Rabbit
Isotype: Ig
Methods: ELISA, IH, IP, WB
Source: Zymed/ Invitrogen
cat# 61-7300, PAD Z-R1
Reference:
Gonzalez-Velasquez, 2008
Formulation: antiserum, PBS, azide, affinity purified
Reactivity:
Reacts in: Dog, Human, Guinea Pig, Mouse, Rat

Immunogen/Epitope

immunogen = 69 kD fusion protein corresp. to aa 463-1109 of human ZO-1 cDNA; the sequence lies N-terminal to the 80 aa region (the α-motif) present in the a+ isoform but absent in the a- isoform due to alternative splicing

Specificity

reacts with the ZO-1α+ and ZO-1α- isoforms. Reactivity with dlg has not been characterized

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References

Paper Citations

  1. . Soluble aggregates of the amyloid-beta protein activate endothelial monolayers for adhesion and subsequent transmigration of monocyte cells. J Neurochem. 2008 Jan;104(2):500-13. PubMed.

Further Reading

No Available Further Reading