Antibody
βIII-tubulin (TuJ-1)
Quick Links
Clonality: monoclonal
Host: Mouse
Isotype: IgG2A
Source: R&D Systems
Cat # MAB1195
References:
Zempel H, 2010
Boland, 2008
Formulation: supernate, protein-A or G-purified, PBS, trehalose, filtered, lyophilized
Reactivity:
Reacts in: Mammal (various), Chicken
Immunogen/Epitope
immunogen = microtubules derived from rat brain
Specificity
neuron specific class III β tubulin; not other β-tubulin in glial cells. Stains neuronal cell bodies, dendrites, axons and axonal terminations
References
Paper Citations
- Zempel H, Thies E, Mandelkow E, Mandelkow EM. Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. J Neurosci. 2010 Sep 8;30(36):11938-50. PubMed.
- Boland B, Kumar A, Lee S, Platt FM, Wegiel J, Yu WH, Nixon RA. Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease. J Neurosci. 2008 Jul 2;28(27):6926-37. PubMed.
Further Reading
No Available Further Reading
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