Antibody

βIII-tubulin (TuJ-1)

Clonality: monoclonal
Host: Mouse
Isotype: IgG2A
Methods: IC, WB
Source: R&D Systems
Cat # MAB1195
References:
Zempel H, 2010
Boland, 2008
Formulation: supernate, protein-A or G-purified, PBS, trehalose, filtered, lyophilized
Reactivity:
Reacts in: Mammal (various), Chicken

Immunogen/Epitope

immunogen = microtubules derived from rat brain

Specificity

neuron specific class III β tubulin; not other β-tubulin in glial cells. Stains neuronal cell bodies, dendrites, axons and axonal terminations

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References

Paper Citations

  1. . Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. J Neurosci. 2010 Sep 8;30(36):11938-50. PubMed.
  2. . Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease. J Neurosci. 2008 Jul 2;28(27):6926-37. PubMed.

Further Reading

No Available Further Reading