Antibody

βIII-Tubulin (SDL.3D10)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG2b
Source: Sigma Aldrich
Cat# T8660
References:
Cahoy, 2008
Papadia, 2008
Marutle, 2007
Darios, 2006
Formulation: liquid, ascites, azide
Reactivity:
Reacts in: Bovine, Human, Rat
<em>not</em> chicken

Immunogen/Epitope

immunogen = synthetic peptide corr. to the C-terminal sequence of human β-tubulin isotype III coupled to BSA

Specificity

specifically recognizes an epitope located on isotype III of β-tubulin; can stimulate microtubule assembly. No cross with other tubulin isotypes.

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References

Paper Citations

  1. Cahoy JD, Emery B, Kaushal A, Foo LC, Zamanian JL, Christopherson KS, Xing Y, Lubischer JL, Krieg PA, Krupenko SA, Thompson WJ, Barres BA. A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. J Neurosci. 2008 Jan 2;28(1):264-78. PubMed.
  2. Papadia S, Soriano FX, Léveillé F, Martel MA, Dakin KA, Hansen HH, Kaindl A, Sifringer M, Fowler J, Stefovska V, McKenzie G, Craigon M, Corriveau R, Ghazal P, Horsburgh K, Yankner BA, Wyllie DJ, Ikonomidou C, Hardingham GE. Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses. Nat Neurosci. 2008 Apr;11(4):476-87. PubMed.
  3. Marutle A, Ohmitsu M, Nilbratt M, Greig NH, Nordberg A, Sugaya K. Modulation of human neural stem cell differentiation in Alzheimer (APP23) transgenic mice by phenserine. Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12506-11. PubMed.
  4. Darios F, Davletov B. Omega-3 and omega-6 fatty acids stimulate cell membrane expansion by acting on syntaxin 3. Nature. 2006 Apr 6;440(7085):813-7. PubMed.

Further Reading

No Available Further Reading