Methods: IH, WB
Source: Synaptic Systems
cell line 2-48
from the lab of Thomas Bayer
Formulation: affinity purified, buffered, azide, lyophilized
Reacts in: Human, Mouse, Rat
Balb/c mice were immunized with a KLH-coupled pyroglutamate-
Abeta-peptide with the peptide pEFRHD-C.
After preparation of the lymph nodes, cells were fused with the myeloma cell line P3-963-Ag8
reactive to N-terminal truncated Abeta 3-X starting with pyroglutamate (pGlu, pE). Does not cross-react with N-terminal truncated Abeta 11-X starting with pGlu.
- Wirths O, Bethge T, Marcello A, Harmeier A, Jawhar S, Lucassen PJ, Multhaup G, Brody DL, Esparza T, Ingelsson M, Kalimo H, Lannfelt L, Bayer TA. Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer's disease cases. J Neural Transm. 2010 Jan;117(1):85-96. PubMed.
No Available Further Reading