Antibody

β-Amyloid [17-24] (4G8)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG2b
Source: Sigma Aldrich
Cat# A1349
reference
Guo, 2006
Formulation: ascites, purified, protein-A, PBS, sterile filtered
Reactivity:
Reacts in: Human, Mouse
mouse at high concentrations

Immunogen/Epitope

immunogen = synthetic peptide corr. to aa 17-24 of β-amyloid, conj. to KLH; Epitope at aa 1-12

Specificity

reactive to aa 17-24 of human amyloid β peptide; also recognizes the precursor forms and abnormally processed isoforms

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References

Paper Citations

  1. Guo JP, Arai T, Miklossy J, McGeer PL. Abeta and tau form soluble complexes that may promote self aggregation of both into the insoluble forms observed in Alzheimer's disease. Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1953-8. PubMed.

Further Reading