Antibody
β-Amyloid, 1-40 (BAM-10)
Quick Links
Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Source: Sigma Aldrich
Cat# A5213
Reference:
AbdAlla, 2008
(unspecified formulation)
Formulation: ascites, azide
Reactivity:
Reacts in: Human
Immunogen/Epitope
immunogen = synthetic β-amyloid peptide (1-40) conjugated to KLH. (Epitope at aa 1-12)
Specificity
stains amyloid plaques within the cortex, and amyloid deposits in blood vessels of brain tissue
References
Paper Citations
- Abdalla S, Lother H, El Missiry A, Langer A, Sergeev P, El Faramawy Y, Quitterer U. Angiotensin II AT2 receptor oligomers mediate G-protein dysfunction in an animal model of Alzheimer disease. J Biol Chem. 2009 Mar 6;284(10):6554-65. PubMed.
Further Reading
News
- Synapses Sizzle in Limelight of Symposium Preceding Neuroscience Conference, Orlando: Day 2
- Paper Alert: Synaptic Activity Increases Aβ Release
- Link Between Synaptic Activity, Aβ Processing Revealed
- Amyloid-β Zaps Synapses by Downregulating Glutamate Receptors
- Sorrento: More Fun, Less Amyloid for Transgenic Mice
- Cortical Hubs Found Capped With Amyloid
- Aβ Production Linked to Oxidative Stress
- Soluble Aβ—Bane or Boon? Real-time Data in Humans Yield New Insight
- Aβ Boosts Memory; Mint/X11 Proteins Boost Aβ?
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