Antibody

Tyrosine Hydroxylase

Clonality: polyclonal
Host: Rabbit
Methods: ELISA, IH, IP, WB
Source: Chemicon and Upstate are Millipore
Cat# AB152
References:
Morawski, 2010
Heneka, 2010
Paleologou, 2010
Kitada, 2007
Yamaguchi, 2007
Formulation: liquid, Ig, affinity purified, HEPES, BSA, glycerol
Reactivity:
Reacts in: Mammal (various)
many non-mammalian

Immunogen/Epitope

immunogen = denatured tyrosine hydroxylase from rat pheochromo cytoma

Specificity

reacts with tyrosine hydroxylase; ~62 kDa by WB;not on paraffin embedded human tissue

Comments / Questions

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References

Paper Citations

  1. . Neurons associated with aggrecan-based perineuronal nets are protected against tau pathology in subcortical regions in Alzheimer's disease. Neuroscience. 2010 Sep 1;169(3):1347-63. PubMed.
  2. . Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6058-63. PubMed.
  3. . Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions. J Neurosci. 2010 Mar 3;30(9):3184-98. PubMed.
  4. . Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11441-6. PubMed.
  5. . Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice. Mol Neurodegener. 2007;2:10. PubMed.

Further Reading

No Available Further Reading