Antibody

TDP-43 phos Ser409/410

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Clonality: polyclonal
Host: Rabbit
Source: Cosmo Bio USA, Inc.
Cat# TIP-PTD-P02
Formulation: liquid, antiserum, azide
Reactivity:
Reacts in: Human

Immunogen/Epitope

immunogen = TDP-43 CMDSKS(p)S(p)GWGM, S(p):phosphoserine 409/410

Specificity

recognizes 43kDa TARDBP only when phosphorylated at Serines 409 and 410; stains ubiquitin-positive inclusions in FTLD-U and ALS without nuclear staining; does not stain ghost tangles and granulovacuolar degeneration in AD or other related diseases

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