Antibody
Tau pS356
Quick Links
Clonality: polyclonal
Host: Rabbit
Source: Biosource Invitrogen
Cat# 44-751G
References:
Kosmidis, 2010
Yuzawa, 2008
Adlard, 2008
Shahani, 2006
Formulation: purified Ig, Dulbecco’s PBS, BSA, azide, glycerol, unconjugated
Reactivity:
Reacts in: Human
expect mouse, rat, rhesus monkey, baboon, cow and goat by homology
Immunogen/Epitope
immunogen = chemically synthesized phosphopeptide derived from the region of human Tau that contains serine 396
Specificity
tau phosphorylated at serine 396
References
Paper Citations
- Kosmidis S, Grammenoudi S, Papanikolopoulou K, Skoulakis EM. Differential effects of Tau on the integrity and function of neurons essential for learning in Drosophila. J Neurosci. 2010 Jan 13;30(2):464-77. PubMed.
- Yuzwa SA, Macauley MS, Heinonen JE, Shan X, Dennis RJ, He Y, Whitworth GE, Stubbs KA, McEachern EJ, Davies GJ, Vocadlo DJ. A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo. Nat Chem Biol. 2008 Aug;4(8):483-90. PubMed.
- Adlard PA, Cherny RA, Finkelstein DI, Gautier E, Robb E, Cortes M, Volitakis I, Liu X, Smith JP, Perez K, Laughton K, Li QX, Charman SA, Nicolazzo JA, Wilkins S, Deleva K, Lynch T, Kok G, Ritchie CW, Tanzi RE, Cappai R, Masters CL, Barnham KJ, Bush AI. Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta. Neuron. 2008 Jul 10;59(1):43-55. PubMed.
- Shahani N, Subramaniam S, Wolf T, Tackenberg C, Brandt R. Tau aggregation and progressive neuronal degeneration in the absence of changes in spine density and morphology after targeted expression of Alzheimer's disease-relevant tau constructs in organotypic hippocampal slices. J Neurosci. 2006 May 31;26(22):6103-14. PubMed.
Further Reading
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