Clonality: polyclonal
Host: Rabbit
Source: MT1
(M Goedert, Medical Research Council, Laboratory of Molecular Biology, Cambridge, England)
Paper, J Neurosci. November 1, 2002
References
Clavaguera, 2009
Reactivity:
Reacts in: Mouse
<em>not</em> human

Immunogen/Epitope

immunogen = synthetic peptide (ARVASKD RTGNDEK), residues 114-127 of the longest isoform of mouse brain tau

Specificity

recognizes the three murine brain tau isoforms but fails to recognize human tau; phosphorylation independent; diffuse neuropil staining

Comments / Questions

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References

Paper Citations

1. Clavaguera F, Bolmont T, Crowther RA, Abramowski D, Frank S, Probst A, Fraser G, Stalder AK, Beibel M, Staufenbiel M, Jucker M, Goedert M, Tolnay M. Transmission and spreading of tauopathy in transgenic mouse brain. Nat Cell Biol. 2009 Jul;11(7):909-13. PubMed.

External Citations

1. J Neurosci. November 1, 2002

Further Reading

No Available Further Reading