Antibody
Tau (1E1/A6)
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Clonality: monoclonal
Host: Mouse
Isotype: IgG
Source: anti-Tau RD4
(R. de Silva and T. Lashley, Reta Lila Weston Institute of Neurological Studies, Windeyer Building, London)
Reference:
Planel, 2008
Reactivity:
reference:<br />deSilva R, Lashley T, et al. <em>Neuropath & Applied Neurobio</em> 29 (3):288, 2003
Immunogen/Epitope
peptide RS1 was designed to represent cognate regions for the 4R-tau isoforms. The RS1 sequence represents the most divergent domain
Specificity
specific responses to the three 4R-tau isoforms. No cross-reactivity was observed either at high recombinant protein concentrations or after prolonged exposure
Note
micro
References
Paper Citations
- Planel E, Krishnamurthy P, Miyasaka T, Liu L, Herman M, Kumar A, Bretteville A, Figueroa HY, Yu WH, Whittington RA, Davies P, Takashima A, Nixon RA, Duff KE. Anesthesia-induced hyperphosphorylation detaches 3-repeat tau from microtubules without affecting their stability in vivo. J Neurosci. 2008 Nov 26;28(48):12798-807. PubMed.
Other Citations
Further Reading
No Available Further Reading
Comments / Questions
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