Antibody

Src phos Tyr416

Clonality: polyclonal
Host: Rabbit
Methods: WB
Source: Cell Signaling
Cat# 2101
Reference:
( Zhang Y, 2010, but see also monoclonal rabbit Cat# 2113 )
Formulation: liquid, protein A and peptide affinity purified, HEPES, saline, BSA, glycerol
Reactivity:
Reacts in: Chicken, Human, Mouse, Rat, Xenopus

Immunogen/Epitope

immunogen = synthetic phosphopeptide corresponding to residues surrounding Tyr416 of human Src

Specificity

detects endogenous levels of Src only when phosphorylated at Tyr416; antibody may cross-react with other Src family members such as Yes, Fyn, Fgr and Yrk when phosphorylated at the equivalent sites

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References

Paper Citations

  1. . Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model. Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19014-9. PubMed.

Further Reading

No Available Further Reading