Antibody

SOD1 mutants (C4F6)

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Clonality: monoclonal
Host: Mouse
Source: C4F6
Makoto Urushitani, Department of Anatomy and Physiology, Laval University Research Centre, Centre Hospitalier de l'Université Laval, Québec, Canada
Paper
Reference:
Bosco DA, 2010
Formulation: liquid
Reactivity:
Reacts in: Human, Mouse

Immunogen/Epitope

Immunogen = recombinant G93A SOD1 protein

Specificity

recognizes the G93A SOD1 and to a lower extent other mutant SOD1 forms, including G37R and G85R; very poor reactivity to the wild type SOD1

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References

Paper Citations

  1. Bosco DA, Morfini G, Karabacak NM, Song Y, Gros-Louis F, Pasinelli P, Goolsby H, Fontaine BA, Lemay N, McKenna-Yasek D, Frosch MP, Agar JN, Julien JP, Brady ST, Brown RH. Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. Nat Neurosci. 2010 Nov;13(11):1396-403. PubMed.

External Citations

  1. Makoto Urushitani
  2. Paper

Further Reading

No Available Further Reading