Antibody

α-Secretase

Tools

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Clonality: kit
Host: Unknown Host
Source: R&D Systems
Cat #
FP001
Reference:
Wang, 2007
Formulation: extraction buffer, reaction buffer, 96 well microplate

Immunogen/Epitope

immunogen = APP
peptide Y E V H H Q K L V using E D A N S D A B C Y L as the reporter system

Specificity

detects enzymatic activity of the α-secretase class of proteases associated with the cleavage of APP

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References

Paper Citations

  1. Wang J, Ho L, Chen L, Zhao Z, Zhao W, Qian X, Humala N, Seror I, Bartholomew S, Rosendorff C, Pasinetti GM. Valsartan lowers brain beta-amyloid protein levels and improves spatial learning in a mouse model of Alzheimer disease. J Clin Invest. 2007 Nov;117(11):3393-402. PubMed.

Further Reading

No Available Further Reading