The Antibodies database was archived in December 2022 and is no longer being updated. The Antibodies database is being supplanted by the AlzAntibodies database, which aims to provide detailed descriptions of selected antibodies.

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Antibodies

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	Name	Source	Clonality & Isotype	Host & Formulation	Method	Reactivity	Immunogen/ Epitope	Specificity	Availability
Plaque-Related From manufacturers (50)
	Neprilysin	LifeSpan Biosciences, Inc.	monoclonal	Mouse	-	Human	immunogen = Nalm6 cell line	neprilysin/CD10/CALLA	-
	Neprilysin	LifeSpan Biosciences, Inc.	monoclonal	Mouse (supernatant)	-	Human, Rat	immunogen = recombinant external domain of CD10 protein	neprilysin/CD10/CALLA	-
	Neprilysin	LifeSpan Biosciences, Inc.	monoclonal	Mouse (supernatant)	-	Human	immunogen = prokaryotic recombinant fusion protein corresp. to the external domain of the CD10 glycoprotein	neprilysin/CD10/CALLA	-
	Neprilysin	LifeSpan Biosciences, Inc.	polyclonal	Rabbit (affinity chromatography)	-	Human	immunogen = recombinant protein encoding aa52-252 of human CD10	neprilysin/CD10/CALLA	-
	Neprilysin	LifeSpan Biosciences, Inc.	monoclonal	Mouse (DEAE-column chromatography)	-	Human	immunogen = purified human CALLA cells	neprilysin/CD10/CALLA	-
	Neprilysin	LifeSpan Biosciences, Inc.	monoclonal	Mouse (Ion exchange chromatography, conj. FITC)	-	Human	-	neprilysin/CD10/CALLA	-
	Neprilysin	LifeSpan Biosciences, Inc.	monoclonal	Mouse (affinity purified, FITC)	-	Human	immunogen = human common acute lymphoblastic leukemia antigen	neprilysin/CD10/CALLA	-
	Neprilysin	LifeSpan Biosciences, Inc.	monoclonal	Mouse (Ion exchange chromatography)	-	Human	-	neprilysin/CD10/CALLA	-
	IDE	Chemicon and Upstate are Millipore	monoclonal IgG1	Mouse (liquid, ascites, no preservative)	-	Human, Monkey, Hamster, Rat	immunogen = IDE purified from human erythrocytes	IDE	-
	IDE	Chemicon and Upstate are Millipore	polyclonal	Rabbit (liquid, serum)	-	Rat	immunogen = synthetic peptide from rat IDE	IDE	-
	Nogo-66 Receptor	Chemicon and Upstate are Millipore	polyclonal	Rabbit (liquid, serum)	-	Human, Mouse, Rat	immunogen = GST fusion protein from mouse NgR	Ngr (Nogo Receptor) native and recombinant	-
	Nogo-A	Chemicon and Upstate are Millipore	polyclonal	Rabbit (liquid, PBS, BSA, azide, affinity purified)	-	Human, Mouse, Rat	immunogen = an 18 amino acid peptide sequence in the middle region of the putative extracellular domain of rat Nogo-A	Nogo-A (neurite outgrowth inhibitor protein A	-
	CLAC-P, NC2-1 region	Chemicon and Upstate are Millipore	polyclonal	Rabbit (liquid, PBS, azide, purified)	-	Human	immunogen = synthetic peptide from the NC2-1 region of human and mouse CLAC-P	CLAC-P (Collagen-like Alzheimer amyloid plaque component), NC2-1 region	-
	CLAC-P, NC2-2 region	Chemicon and Upstate are Millipore	polyclonal	Rabbit (liquid, PBS, azide, affinity purified)	-	Human	immunogen = synthetic peptide from the NC2-2 region of human and mouse CLAC-P	CLAC-P (Collagen-like Alzheimer amyloid plaque component), NC2-2 region	-
	CLAC-P, NC2-3 region	Chemicon and Upstate are Millipore	polyclonal	Rabbit (liquid, PBS, azide, affinity purified)	-	Human	immunogen = synthetic peptide from the NC3 region of human CLAC-P	CLAC-P (Collagen-like Alzheimer amyloid plaque component), NC3 region	-
	Nogo-B	Chemicon and Upstate are Millipore	polyclonal	Rabbit (liquid, affinity purified Ig, Tris, BSA, azide)	-	Human, Mouse, Rat	immunogen = 12 a.a. peptide sequence within the N-terminus and at the splice site of Nogo-A from the putative extracellular domain of rat Nogo-B	neurite outgrowth inhibitor B (Nogo-B); immunogen sequence is present only in Nogo-B	-
	Nogo-A/B/C	Chemicon and Upstate are Millipore	polyclonal	Rabbit (liquid, PBS, BSA, azide, affinity purified)	-	Human, Mouse, Rat	immunogen = a 13 amino acid peptide between the putative 2nd-3rd transmembrane domain of human Nogo-A	Nogo-A, B, C	-
	CLAC-P	Novus Biologicals	polyclonal IgG	Rabbit (liquid, antisera)	-	Human, Mouse	immunogen = synthetic peptide mapping to residues 155-169 (KGEQGDQGPRMVFPK) of the NC2-2 region of human and mouse CLAC-P	Reacts with residues 155-169 of the NC2-2 region of human and mouse CLAC-P. Detects bands of 50, 70 and 100 kDa in SPs of AD brain, but not in diffuse plaques of non-demented aged individuals, diffuse deposits in sub-cortical structures and cerebellum in AD nor in cerebral amyloid angiopathy	-
	CLAC-P	Novus Biologicals	polyclonal IgG	Rabbit (liquid, antisera)	-	Human	immunogen = synthetic peptide mapping to residues 430-443 (DYNGNLH EALQRIT) of the NC3 region of human and mouse CLAC-P	detects full-length CLAC-P and the secreted form of CLAC-P protein. It does not react with full-length or secreted forms of COLXIII protein or the COLXXIII protein	-
	Nogo 66 receptor	Novus Biologicals	polyclonal IgG	Goat (liquid, affinity purified antisera, Tris saline, BSA, azide)	-	Dog, Human, Mouse, Rat	immunogen = synthetic peptide with sequence C-LQALPDDTFRDLGN, representing the internal region of the human protein according to NP_075380.1	specific for Nogo 66 receptor	-
	Nogo-A/B	Novus Biologicals	polyclonal IgG	Rabbit (liquid, whole antisera, PBS, gelatin, azide)	-	Human, Mouse, Rat	immunogen = a portion of amino acids 1-50 of human Nogo-B	recognizes Nogo-A (approx. 220 kD)and Nogo-B2 and B1 (approx. 50 kD and 48 kD in human and 43 kD and 41 kD in mouse and rat, respectively)	-
	IDE	Novus Biologicals	polyclonal IgG	Goat (liquid, affinity purified antisera, Tris-saline, BSA, azide)	-	Mouse, Rat	immunogen = synthetic peptide, C-QQYNYDRDNIE, representing the internal region of the sequence according to NP_112419.2	specific for IDE; observed 110 kDa by WB	-
	IDE /Insulysin	Novus Biologicals	polyclonal IgG	Goat (liquid, affinity purified antisera, Tris-saline, BSA, azide)	-	Human	immunogen = synthetic peptide, C-QQYNFDRDNTE, representing the internal region of the sequence according to NP_004960.1	specific for IDE; observed 110-120 kDa by WB	-
	IDE	Novus Biologicals	polyclonal	Mouse (liquid, antisera, glycerol, no preservative)	-	Human	immunogen = IDE (NP_004960, a.a. 920~1020) partial recombinant protein with GST tag.	reactive against IDE: cell lysate and recombinant protein	-
	IDE	Abcam	polyclonal IgG	Rabbit (liquid, BSA, borate buffered saline, azide, affinity purified)	-	Mouse, Rat	immunogen = synthetic peptide derived from within residues 950 to the C-terminus of human insulin degrading enzyme / IDE	IDE	-
	IDE	Abnova Corporation	polyclonal IgG	Mouse (liquid, glycerol)	-	Human	immunogen = partial recombinant IDE, aa 920-1020	IDE	-
	Ngr	A D I	polyclonal IgG	Rabbit (liquid, affinity purified)	-	Human, Monkey, Mouse, Rat	immunogen = A 17-aa synthetic peptide within the C-terminus of human Ngr conj. to KLH	Ngr (Nogo receptor)	-
	CLAC-P NC2-1 region	CEDARLANE Laboratories	polyclonal	Rabbit	-	-	-	-	-
	Neprilysin /CD10 (RXB.14)	ID Labs Biotechnology	monoclonal	Mouse (FITC conj)	-	Human	-	-	-
	CLAC-P, NC2-1 region	RDI /Fitzgerald	polyclonal IgG	Rabbit (liquid, PBS, azide, affinity purified)	-	Human, Mouse	immunogen = residues 171-183 of the NC2-1 region of human and mouse CLAP	reacts with residues 171-183 [N H G F L S A D Q Q L I K] of the NC2-1 region of CLAC-P (50, 70, 100 kDa). Not with diffuse plaques of non-demented aged individuals, diffuse deposits in sub-cortical structures and cerebellum in AD nor in cerebral amyloid angiopathy	-
	Neprilysin /CD10 (B-E3)	DIACLONE	monoclonal IgG2a	Mouse (liquid, PBS, sterile filtered, low-endotoxin, no preservative)	-	Human	immunogen = Daudi and Raji cell lines	recognizes CD10 (CALLA), 100kDa	-
	Neprilysin /CD10 (MEM-78)	DIACLONE	monoclonal IgG1	Mouse (liquid, protein-A purified, PBS, azide, BSA, conj. to FITC)	-	Human	immunogen = Pre-B cell line NALM-6	recognizes CD10 (CALLA)	-
	Neprilysin /CD10 (B-E3)	DIACLONE	monoclonal IgG2a	Mouse (liquid, PBS, BSA, azide, ion-exchange purified)	-	Human	immunogen = Daudi and Raji cell lines	recognizes CD10 (CALLA) 100kDa	-
	Neprilysin /CD10 (B-E3)	DIACLONE	monoclonal IgG2a	Mouse (lyophilized, PBS, BSA, azide, ion-exchange purified, PE conj.)	-	Human	immunogen = Daudi and Raji cell lines	recognizes CD10 (CALLA) 100kDa	-
	Neprilysin /CD10 (B-E3)	DIACLONE	monoclonal IgG2a	Mouse (liquid, PBS, BSA, azide, ion-exchange purified, unconjugated)	-	Human	immunogen = Daudi and Raji cell lines	recognizes CD10 (CALLA) 100kDa	-
	Neprilysin /CD10 (56C6)	Diagnostic Biosystems	monoclonal IgG1	Mouse (pretitered, ready to use)	-	Human	immunogen = prokaryotic recombinant protein corresp. to the external domain of the CD10 glycoprotein	CD10 (CALLA) 100kDa;identified on the surface of early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue	-
	Neprilysin /CD10 (56C6)	Diagnostic Biosystems	monoclonal IgG1	Mouse (tissue culture supernatant, azide)	-	Human	immunogen = prokaryotic recombinant protein corresp. to the external domain of the CD10 glycoprotein	specific to CD10 (CALLA) 100kDa;identified on the surface of early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue	-
	IDE /insulysin, C terminal	Acris Antibodies	polyclonal	Rabbit (liquid, glycerol, azide, affinity purified)	-	Human, Mouse	immunogen = synthetic peptide based on the C-terminal end of human Insulysin	IDE/ Insulysin	-
	Ngr	Biotrend	polyclonal IgG	Rabbit (liquid, affinity purified)	-	Human, Monkey, Mouse, Rat	immunogen = A 17-aa synthetic peptide within the C-terminus of human Ngr, conjugated to KLH	Ngr (Nogo receptor)	-
	CLAC, NC2-1 region	GeneTex	polyclonal IgG	Rabbit (liquid, PBS, azide, affinity purified)	-	Human, Mouse	immunogen = residues 171-183 (N H G F L S A D Q Q L I K) of the NC2-1 region of human and mouse CLAC-P	CLAC-P (NC2-1 region (50, 70 and 100 kDa)	-
	CLAC-P, NC2-1 region	GenWay Biotech	polyclonal	Rabbit (liquid, PBS, azide, affinity purified)	-	Human, Mouse	immunogen: reacts with residues 171-183 [N H G F L S A D Q Q L I K] of the NC2-1 region of human and mouse CLAC-P	CLAP-P, NC2-1 region	-
	CLAC-P, NC2-1 region	KOMA BIOTECH	polyclonal IgG	Rabbit (purified, PBS, azide)	-	Human, Mouse	immunogen = Synthetic peptide 171-183 [N H G F L S D Q I K] of the NC2-1region of human /mouse CLAC-P	CLAC-P, NC2-1	-
	Neprilysin	LifeSpan Biosciences, Inc.	monoclonal	Mouse (protein G purified)	-	Human	immunogen = Partially purified cell membrane antigens from fresh leukemia cells	neprilysin/CD10/CALLA	-
	CLAC-P, NC2-1 region	Neuromics	polyclonal IgG	Rabbit (liquid, affinity purified)	-	Human	Immunogen = (a.a. 171-183); NC2-1 region of human and mouse CLAC-P	-	-
	CLAC-P	Novus Biologicals	polyclonal IgG	Rabbit (liquid, antisera)	-	Human, Mouse	immunogen = synthetic peptide mapping to residues 171-183 (NHGFLSA DQQLIK) of the NC2-1 region of human and mouse CLAC-P	Reacts with residues 171-183 of the NC2-1 region of human and mouse CLAC-P. Detects bands of 50, 70 and 100 kDa in SPs of AD brain, but not in diffuse plaques of non-demented aged individuals, diffuse deposits in sub-cortical structures and cerebellum in AD nor in cerebral amyloid angiopathy	-
	IDE /Insulysin	R&D Systems	polyclonal IgG	Goat (lyophilized, PBS, trehalose, affinity purified)	-	Human	immunogen = purified, Sf 21-derived recombinant human isulysin, aa 42-1019	Insulysin	-
	IDE	Santa Cruz	polyclonal IgG	Goat (liquid, PBS, gelatin, azide, affinity purified; sc-27266P blocking peptide)	-	Human, Mouse, Rat	immunogen = peptide mapping near the c-terminus of human IDE	IDE	-
	Nogo A (17)	BD Transduction	monoclonal IgG1	Mouse (liquid, BSA, glycerol, azide)	-	Rat	immunogen = peptide corresp. to aa 424-627 of rat Nogo-A	Nogo-A	-
	CLAC-P, NC2-1 region	US Biological	polyclonal IgG	Rabbit (liquid, PBS, azide, affinity purified)	-	Human, Mouse	immunogen = CLAC-P, NC2-1 region, aa 171-183, (N H G F L S A D Q Q L I K)	CLAC-P, NC2-1 region (aa 171-183); bands at 50, 70 and 100kD in SPs of AD brain, but not in diffuse plaques of non-demented aged individuals, diffuse deposits in sub-cortical structures and cerebellum in AD nor in CAA	-
	IDE	Santa Cruz	polyclonal IgG	Goat (liquid, affinity purified, PBS, azide, gelatin)	-	Human, Mouse, Rat	immunogen = apeptide mapping near the C-terminus of IDE of human origin.	for detection of IDE	-