|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, PBS, BSA, protein A purified) |
WB |
Human |
immunogen = recombinant full length protein human BACE: solubilized total recombinant protein |
BACE1; cross-reactivity with BACE2 is almost negligible |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, whole serum, azide) |
WB |
Human |
immunogen = synthetic peptide (I R L P L R S G L G G A P L G L R L P R) corresp. to aa 26-45 of human BACE1 |
proBACE; not mature BACE |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, affinity purified, PBS, BSA, azide) |
WB |
Human |
immunogen = synthetic peptide, corr. to aa 441-457 of human BACE2 |
~58 kDa BACE2 |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, affinity purified, PBS, BSA, azide) |
WB |
Human |
immunogen = synthetic peptide, corr. to aa 503-518 of human BACE2 |
~58 kDa BACE2 |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(IgG fraction, affinity purified, PBS, azide) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide, corr. to aa 496-511 of human BACE2 |
BACE2 |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(IgG fraction, purified, PBS, azide) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide, corr. to aa 44-59 of human BACE2 |
BACE2 |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, glyceerol, azide, affinity purified) |
WB |
Human |
immunogen = synthetic peptide based on cytoplasmic domain of human BACE1 |
recognizes all four of the splice variants of BACE1 |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, glycerol, azide, affinity purified) |
WB |
Human |
immunogen = synthetic peptide based on stalk region of human BACE1 |
recognizes all four of the splice variants of BACE1 |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, glycerol, azide, affinity purified) |
WB |
Human |
immunogen = synthetic peptide based on catalytic domain of human BACE2 |
recognizes all three of the splice variants of BACE2. |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, glycerol, azide, affinity purified) |
WB |
Human |
immunogen = synthetic peptide based on cytoplasmic domain of human BACE2 |
recognizes the two longest of the splice variants of BACE2 |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, glycerol, azide, affinity purified) |
WB |
Human |
immunogen = synthetic peptide based on stalk region of human BACE2 |
recognizes the two longest of the splice variants of BACE2 |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, affinity purified, BSA, PBS, azide) |
WB |
Human |
immunogen = synthetic peptide, C L R Q Q H D D F A D D I S L L K, aa 458-501 of human BACE |
Transfected BACE1 |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, whole serum, azide) |
IH |
Human |
immunogen = synthetic peptide, C L R Q Q H D D F A D D I S L L K, aa 458-501 of human BACE |
70 kDa BACE, plasma membrane |
- |
|
|
Biomol Enzo Life Sciences |
polyclonal
|
Rabbit
(liquid, PBS, glycerol, azide, affinity purified) |
IB |
Human, Mouse, Rat |
immunogen = synthetic peptide based on the catalytic domain of the human BACE1 seq. |
recognizes zymogen and mature BACE1; no cross with BACE2 |
- |
|
|
Biosource Invitrogen |
polyclonal
|
Rabbit
(processed whole serum, azide) |
WB |
Human |
immunogen = synthetic peptide, corr. to C-terminal 15 residues of human β-secretase 1 |
proBACE, and mature BACE |
- |
|
|
Zymed/ Invitrogen |
polyclonal
|
Rabbit
(affinity purified, PBS, azide) |
WB |
Mouse |
immunogen = synthetic peptide derived from the C-terminal region of human BACE |
C-terminal region of mouse BACE |
- |
|
|
Zymed/ Invitrogen |
polyclonal
|
Rabbit
(affinity purified, PBS, azide) |
WB |
Mouse |
immunogen = synthetic peptide derived from the C-terminal region of human BACE 2 |
C-terminal region of mouse BACE 2 |
- |
|
|
Zymed/ Invitrogen |
polyclonal
|
Rabbit
(affinity purified, PBS, azide) |
WB |
Mouse |
immunogen = synthetic peptide derived from the mid region of human BACE 2 |
reacts with mid region on BACE 2 (60-70 kDa) |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, PBS, azide, puriafied) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide, corresp. to aa 485-501 of human BACE |
BACE |
- |
|
|
AbD Serotec |
polyclonal
|
Goat
(liquid, serum, purified, azide) |
IH |
Human |
immunogen = synthetic peptide, C L R Q Q H D D F A D D I S L L K, corresp.to the C-terminal aa seq. 458-501 of human BACE |
BACE, C-terminal |
- |
|
|
AbD Serotec |
polyclonal
IgG |
Rabbit
(liquid, Ig, purified, PBS, azide) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide corresp. to aa 44-59, N-terminal of human BACE2 |
BACE2, N-terminal |
- |
|
|
AbD Serotec |
polyclonal
IgG |
Rat
(liquid, Ig, purified, PBS, azide) |
IH |
Human, Mouse, Rat |
immunogen = synthetic peptide near N-terminal of human BACE1 |
BACE1 |
- |
|
|
ProSci |
polyclonal
IgG |
Rabbit
(purified, azide, Store at -20°) |
WB |
Human, Mouse |
immunogen = aa 485 to 501, (C L R Q Q H D D F A D D I S L L K) of human BACE |
70 kDa BACE |
- |
|
|
ProSci |
polyclonal
IgG |
Rabbit
(liquid, purified, PBS, azide) |
IB |
Human |
immunogen = synthetic peptide corr. to aa. 496-511 near the C-terminal of human BACE2 |
~75 kDa BACE2 protein |
- |
|
|
ProSci |
polyclonal
IgG |
Rabbit
(liquid, purified, azide) |
IB |
Human, Mouse, Rat |
immunogen = synthetic peptide corr. to aa. 44-59 near the N-terminal of human BACE2 |
~75 kDa BACE2 protein |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(liquid, PBS, azide) |
IH |
Human |
immunogen = synthetic peptide of internal domain of human BACE1, conj. KLH |
BACE 1 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(liquid, affinity purified) |
IH |
Human |
immunogen = synthetic peptide near the N-terminus of human BACE1, conj. KLH |
BACE 1 |
- |
|
|
LifeSpan Biosciences, Inc. Cat# cat# LS-C377 |
polyclonal
|
Rabbit
(liquid, PBS, azide, ion exchange chromatography) |
IC, WB |
Human, Mouse |
immunogen = synthetic peptide corresp. to 17 aa near the CT of human BACE |
BACE 1 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Goat
(unpurified serum) |
ELISA, IH |
Human |
immunogen = synthetic peptide (C L R Q Q H D D F A D D I S L L K) |
recognizes the C-terminal aa sequence 485-501 of human beta amyloid cleaving enzyme protein |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Goat
(unpurified serum) |
ELISA, WB |
Human |
immunogen = synthetic peptide 17 aa within the cytoplasmic, C-terminal domain of the rat NHE4, conj. KLH |
BACE1 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Goat
(unpurified serum) |
ELISA, WB |
Human |
immunogen = synthetic peptide 10 aa peptide near the NT of mouse BACE/Asp2 |
BACE1 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(DEAE-column chromatography) |
ELISA, IF, IH, WB |
Mouse |
immunogen = synthetic peptide corresp. to 10 aa near the NT of mouse BACE/Asp2 conjugated to KLH |
BACE 1 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(DEAE-column chromatography) |
ELISA, WB |
Mouse |
immunogen = synthetic peptide 10 aa peptide near the NT of mouse BACE/Asp2, conj. to KLH |
BACE/Asp2 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(DEAE-column chromatography) |
ELISA, WB |
Human |
immunogen = synthetic peptide 17 aa peptide near the CT of human BACE/Asp2, conj. to KLH |
BACE/Asp2 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
|
ELISA |
Human |
immunogen = synthetic peptide conjugated to KLH |
BACE 1 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
|
ELISA |
Human |
immunogen = synthetic peptide conjugated to KLH |
BACE 1 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
|
ELISA |
Human |
immunogen = synthetic peptide conjugated to KLH |
BACE 1 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(protein A purified) |
WB |
Human |
immunogen = solubilized total recombinant protein |
BACE 1; cross-reactivity with BACE2 is almost negligible |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(unpurified serum) |
WB |
Human |
immunogen = synthetic peptide corresp. to aa sequence 26-45 of BACE1 |
BACE 1; proBACE; does not detect mature BACE |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Goat
(unpurified serum) |
IH |
Human |
immunogen = synthetic peptide C L R Q Q H D D F A D D I S L L K corresp. to the C-terminal aa458-501 of human BACE |
recognizes beta amyloid cleaving enzyme (BACE), a 70kD aspartic protease |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(DEAE-column chromatography) |
WB |
Mouse |
immunogen = synthetic peptide derived from the C-terminal region of the human BACE protein |
recognizes C-terminal of BACE protein |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(DEAE-column chromatography) |
WB |
Human |
immunogen = synthetic peptide corresponding to aa 485-501 (C485 L R Q Q H D D) |
recognizes secretase. (~70kDa) |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Goat
|
WB |
Human |
- |
BACE1 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(unpurified serum) |
WB |
Human |
immunogen = synthetic peptide corresp. to aa46-65 (E T D E E P E E P G R R G S F V E M V D) of human BACE1 |
proBACE and mature BACE |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(DEAE-column chromatography) |
ELISA, IF, IH, WB |
Human |
immunogen = synthetic peptide of 20 aa near the CT of human BACE2/Asp1, conjugated to KLH |
BACE/Asp2; no significant sequence homology exists with BACE2/Aps1, a homolog of BACE, or other Asps |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(PBS, azide, affinity purified) |
IH, WB |
Human, Mouse, Rat |
immunogen = synthetic peptide (A P T P G P G T P A E R H A D G) corresp. to aa 44 to 59 of human BACE2 |
BACE2 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(PBS, azide, affinity purified) |
IH, WB |
Human |
immunogen = synthetic peptide corresp. to aa near the C- terminus of human BACE2 |
BACE2 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(unpurified serum) |
ELISA, WB |
Human |
immunogen = 20 aa synthetic peptide near the CT of human BACE2/Asp1 conjugated to KLH BACE2 |
BACE2/Asp2; no seq. homology exists with BACE2/Aps1 or other Asps |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
|
ELISA |
Human |
immunogen = synthetic peptide conj. to KLH |
BACE2 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
|
ELISA |
Human |
immunogen = synthetic peptide conj. to KLH |
BACE2 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
|
ELISA |
Human |
immunogen = synthetic peptide conj. to KLH |
BACE2 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(DEAE-column chromatography) |
WB |
Human, Mouse |
immunogen = synthetic peptide derived from the C-terminal seq. of the human BACE 2 protein |
C-terminal region of BACE2 protein |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(IgG fract.) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide corresp. to aa 44-59 of human BACE2 |
BACE2 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(DEAE-column chromatography) |
WB |
Human, Mouse |
immunogen = synthetic peptide derived from the mid-region of human BACE 2 protein |
mid-region of BACE2 protein |
- |
|
|
Chemicon and Upstate are Millipore |
monoclonal
IgG1 |
Mouse
(purified, PBS, azide) |
IC, IH, IP, WB |
Primate (various), Human, Mouse, Rat |
immunogen = synthetic peptide, C-terminus of BACE |
BACE, not BACE2; recognizes pro and mature forms |
- |
|
|
Chemicon and Upstate are Millipore |
polyclonal
|
Rabbit
(liquid, serum, affinity purified, PBS, azide) |
IH, WB |
Human, Monkey, Mouse, Rat |
immunogen = synthetic peptide corresponding to C-terminus of human BACE |
BACE; recognizes a band of ~70-75 kDa. and at ~45 kDa |
- |
|
|
Chemicon and Upstate are Millipore |
polyclonal
|
Rabbit
(liquid, serum) |
IP, WB |
Human, Mouse, Rat |
immunogen = synthetic peptide from the C-terminus of human BACE2 |
BACE2 |
- |
|
|
R&D Systems |
kit
|
Unknown Host
(extraction buffer, reaction buffer, 96 well microplate) |
IF |
- |
immunogen = APPpeptide REEVNLDAEFKR using EDANS/DABCYL as the reporter system |
detects enzymatic activity of the β-secretase class of proteases associated withthe cleavage of APP |
- |
|
|
R&D Systems |
kit
|
Unknown Host
(extraction buffer, reaction buffer, 96 well microplate) |
IF |
- |
immunogen = APPpeptide GVVIATVIV using EDANS/DABCYL as the reporter system |
detects enzymatic activity of the γ-secretase class of proteases associated withthe cleavage of APP |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, PBS, azide, affinity purified) |
IH |
Human, Mouse, Rat |
immunogen = synthetic peptide from the N- terminus of human BACE1, conjugated to KLH |
BACE |
- |
|
|
A B R - Thermo Scientific |
polyclonal
IgG |
Rabbit
(liquid, IgG fraction, PBS, azide) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide, C-terminal residues C(485) L R Q Q H D D F A D D I S L L K(501) |
β-secretase 1 |
- |
|
|
A B R - Thermo Scientific |
polyclonal
IgG |
Rabbit
(affinity purified PBS, azide) |
WB |
Human |
immunogen = synthetic peptide, C Q R R P R D P E V V N D E S S (aa. 496-511) of human β-secretase 2 |
~75 kDa β-secretase 2 |
- |
|
|
A B R - Thermo Scientific |
polyclonal
IgG |
Rabbit
(liquid, purified, PBS, azide) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide, A P T P G P G T P A E R H A D G (aa 44-59) of human β-secretase 2 |
β-secretase 2 |
- |
|
|
A B R - Thermo Scientific |
polyclonal
IgG |
Rabbit
(epitope affinity purified, PBS, BSA, azide) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide, V S E I S G P F S T E D I A S N C (aa. 441-457) of human β-secretase 2 |
human β-secretase 2 from transfected cells. |
- |
|
|
A D I |
polyclonal
|
Rabbit
(liquid, serum or affinity purified) |
ELISA, WB |
Mouse, Rat |
immunogen = a 17 aa peptide, designated BACE11-P control peptides, near the CT of human BACE/Asp2, KLH conj. |
BACE/Asp2 only, not BACE2/Asp1 |
- |
|
|
A D I |
polyclonal
|
Rabbit
(serum, agarose purified or affinity purified) |
ELISA, WB |
Human |
immunogen = a 20 aa peptide, designated BACE21-P control peptides, near the CT of human BACE2/Asp1, KLH conj. |
BACE2/Asp1 |
- |
|
|
A D I |
monoclonal
|
(Peptide Substrate, Store at -20°) |
- |
- |
immunogen = 14 aa peptide of human APP 590-603Acetyl-EISEVNL DA EFR D-amide |
|
- |
|
|
A D I |
monoclonal
|
(Peptide Substrate, Store at -20°) |
- |
- |
immunogen = 14 aa peptide of human APP 590-603 Acetyl-E I S E V K M D A E F R D-amide |
|
- |
|
|
Calbiochem EMD Biosciences |
polyclonal
IgG |
Rabbit
(liquid, serum, no preserve) |
IP, WB |
Human, Hamster |
immunogen = synthetic peptide, C-R Q Q H D D F A D D I S L L K, corresp. to aa 487-501 of human BACE |
recognizes the ~65 and ~75 kDa glycosylated forms of BACE protein |
- |
|
|
Calbiochem EMD Biosciences |
polyclonal
IgG |
Rabbit
(liquid, affinity purified, PBS, azide) |
WB |
Human |
immunogen = synthetic peptide corresp. to aa. 496-511 of human BACE2 |
~75 kDa BACE2 protein; cross-reacts with 52 kDa and 39 kDa unknown protein |
- |
|
|
Calbiochem EMD Biosciences |
polyclonal
IgG |
Rabbit
(liquid, affinity purified, PBS, azide) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide corresp. to aa 44-59 of human BACE2 |
~75 kDa BACE2 protein |
- |
|
|
Chemicon and Upstate are Millipore |
polyclonal
IgG |
Goat
(serum, thimerosal) |
ELISA, IH, WB |
Human |
immunogen = synthetic peptide corresponding to aa 485-501 of BACE |
70 kDa glycosylated form of BACE. |
- |
|
|
Exalpha Biologicals |
polyclonal
IgG |
Rabbit
(purified, PBS, azide) |
WB |
Human, Mouse |
synthetic peptide, aa485-501 of human BACE, C-terminal |
70 kDa BACE |
- |
|
|
Exalpha Biologicals |
polyclonal
IgG |
Rabbit
(purified, PBS, azide) |
WB |
Human, Mouse, Rat |
synthetic peptide, aa44-59 of human BACE2, N-terminal |
70 kDa BACE2 |
- |
|
|
Exalpha Biologicals |
polyclonal
IgG |
Rabbit
(purified, PBS, azide) |
WB |
Human, Mouse, Rat |
synthetic peptide, aa496-511 of human BACE2, C- terminal |
70 kDa BACE2 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(liquid, PBS, azide, affinity purified) |
IH |
Human |
immunogen = synthetic peptide near the N-terminus of human BACE1, conj. KLH |
BACE 1 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
IgG |
Rabbit
(liquid, PBS) |
IH |
Human |
immunogen = synthetic peptide near the N-terminal of human BACE1 |
BACE 1 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
|
WB |
- |
- |
BACE 1 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
IgG |
Rabbit
(liquid, PBS) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide corresp. to aa 44-59 of human BACE2 (N-terminal) |
BACE2 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
|
WB |
Human, Mouse, Rat |
- |
BACE2 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
IgG |
Sheep
(lyophilized, PBS, affinity purified) |
ELISA, IP, WB |
Human |
immunogen = NS0-derived rhBACE-2 (aa63-466) |
BACE2 |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(liquid, PBS, azide, purified) |
IH, WB |
Human, Mouse, Rat |
immunogen = synthetic peptide corresp. to aa 44-59 of human BACE2 |
BACE2 |
- |
|
|
Novus Biologicals |
polyclonal
IgG |
Rabbit
(liquid, affinity purified, BSA, PBS, azide) |
WB |
Human |
immunogen = synthetic peptide, C L R Q Q H D D F A D D I S L L K, aa 458-501 of human BACE |
Transfected BACE1 |
- |
|
|
Novus Biologicals |
polyclonal
IgG |
Rabbit
(liquid, affinity purified, PBS, BSA, azide) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide, V S E I S G P F S T E D I A S N C, aa441-457 of human BACE2 |
BACE2 |
- |
|
|
Novus Biologicals |
polyclonal
IgG |
Rabbit
(liquid, affinity purified, PBS, BSA, azide) |
WB |
Human |
immunogen = synthetic peptide, C P E V V N D E S S LV R H R W K, aa 503-518 of human BACE2 |
BACE2 |
- |
|
|
Novus Biologicals |
polyclonal
IgG |
Rabbit
(liquid antisera, PBS, azide, purified) |
WB |
Human, Mouse, Rat |
immunogen = Synthetic peptide, corresp. to aa. 485-501 of Human BACE; peptide sequence differs from those of mouse and rat BACE by one amino acid |
detects the 70 kD band of BACE |
- |
|
|
A B R - Thermo Scientific |
polyclonal
IgG |
Rabbit
(liquid, affinity purified, PBS, BSA, azide) |
ELISA, IP, WB |
Human, Mouse |
immunogen = synthetic peptide, C L R Q Q H D D F A D D I S L L K, aa485-501 of human β-secretase 1 |
transfected β-secretase 1 |
- |
|
|
A B R - Thermo Scientific |
polyclonal
IgG |
Rabbit
(affinity purified, azide) |
IF, WB |
Human |
immunogen = synthetic peptide, aa. 122-131 of human β-secretase 1 |
β-secretase 1 |
- |
|
|
A B R - Thermo Scientific |
monoclonal
IgG |
Mouse
(liquid) |
ELISA, IH, WB |
Human |
immunogen = beta-Secretase 1 (aa 22~502) full length recombinant protein with GST tag |
β-secretase 1 |
- |
|
|
A B R - Thermo Scientific |
polyclonal
IgG |
Goat
(liquid, whole antiserum, azide) |
IH |
Human |
immunogen = synthetic peptide, corresp. to C-terminal residues C L R Q Q H D D F A D D I S L L K(aa 485-501) of the human β-secretase 1 protein |
β-secretase 1 |
- |
|
|
A B R - Thermo Scientific |
polyclonal
IgG |
Rabbit
(liquid, affinity purified, PBS, BSA, azide) |
WB |
Human, Mouse |
immunogen = synthetic peptide, C-P E V V N D E S S L V R H R W K (aa 503-518) of human β-secretase 2 |
human β-secretase 2 from transfected cells. |
- |
|
|
R&D Systems |
monoclonal
IgG1 |
Mouse
(IgG fract, protein-G, PBS, trehalose, lyophilized) |
ELISA, IP, Neut, WB |
Human |
immunogen = purified, NS0-derived recombinant human BACE-1 ectodomain (aa 22-460) |
rhBACE-1, ectodomain |
- |
|
|
R&D Systems |
polyclonal
|
Goat
(affinity purified, PBS, lyophilized) |
ELISA, WB |
Human |
immunogen = purified, NS0-derived recombinant human BACE-1 ectodomain |
rhBACE-1 |
- |
|
|
R&D Systems |
polyclonal
IgG |
Goat
(affinity purified, Biotin, PBS, lyophilized) |
WB |
Human |
immunogen = purified, NS0-derived recombinant human BACE-1 ectodomain |
BACE-1 |
- |
|
|
R&D Systems |
monoclonal
IgG1 |
Mouse
(IgG fract, protein-G, PBS, trehalose, lyophilized) |
ELISA, FC, IC, WB |
Human |
immunogen = purified, NS0-derived recombinant human BACE-1 ectodomain (aa 22-460) |
rhBACE-1 |
- |
|
|
R&D Systems |
monoclonal
IgG1 |
Mouse
(liquid, PBS, azide, CFS conj.) |
FC |
Human |
|
intended to identify and quantitate cells expressing cytoplasmic forms of the protein rhBACE-1 |
- |
|
|
R&D Systems |
polyclonal
IgG |
Sheep
(affinity purified, filtered, PBS, trehalose, lyophilized) |
ELISA, IP, WB |
Human, Mouse |
immunogen = purified, NS0-derived recombinant human BACE-2, aa 63-466 |
recognizes human BACE-2; |
- |