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Antibodies

168 Results

Name Source Clonality &
Isotype
Host &
Formulation
Method Reactivity Immunogen/
Epitope
Specificity Availability
α-, β-, γ-secretase From labs (1)
7523(C. HaassPaper)Reference: Rajendran, 2006 polyclonal
Rabbit
IC, IP, WB Human - N terminus (amino acids 46-60) -
α-, β-, γ-secretase From manufacturers (67)
Abcam polyclonal
IgG
Rabbit
(liquid, PBS, azide, affinity purified)
IH Human immunogen = synthetic peptide from an internal seq. of human BACE1, conj. to KLH BACE1 -
Abcam polyclonal
IgG
Rabbit
(liquid, affinity purified, BSA, PBS, azide)
WB Human immunogen = synthetic peptide, C L R Q Q H D D F A D D I S L L K, aa 458-501 of human BACE Transfected BACE1 -
Abcam polyclonal
IgG
Rabbit
(liquid, glycerol, azide, affinity purified)
WB Human immunogen = synthetic peptide based on catalytic domain of human BACE1 recognizes all four of the splice variants of BACE1 -
Chemicon and Upstate are Millipore polyclonal
Ig
Rabbit
(purified, PBS, azide)
WB Human, Mouse immunogen = synthetic peptide corr. to aa 458-501 of BACE recognizes BACE -
Abcam polyclonal
IgG
Rabbit
(liquid, whole serum, azide)
WB Human immunogen = synthetic peptide (E T D E E P E E P G R R G S F V E M V D) corresp. to aa 46-65 of human BACE1 proBACE and mature BACE -
Abcam polyclonal
IgG
Rabbit
(liquid, whole serum, azide)
WB Human immunogen = synthetic peptide (R Q Q H D D F A D D I S L L K) corresp. to aa 487-501 of human BACE1 proBACE and mature BACE -
Abcam polyclonal
IgG
Rabbit
(liquid, PBS, azide, affinity purified)
WB Human, Mouse, Rat immunogen = synthetic peptide, A P T P G P G T P A E R H A D G, corresp. to aa 44-59 of human BACE2 BACE2 -
A D I polyclonal
Rabbit
(serum, or affinity purified)
ELISA, WB Human, Rat immunogen = a 10 aa peptide, designated BACE12-P control peptide, near the extracellular NT of mouse BACE/Asp2, KLH conj. BACE/Asp2 only, not BACE2/Asp1 -
Biosource Invitrogen polyclonal
IgG
Rabbit
(affinity purified, PBS, BSA, azide)
WB Human immunogen = solubilized total recombinant protein BACE1, 70 kDa -
Biosource Invitrogen polyclonal
Rabbit
(liquid, PBS, azide, affinity purified)
WB Mouse immunogen = synthetic peptide derived from the C-terminal seq. of the human BACE-2 protein BACE-2 -
Biosource Invitrogen polyclonal
Rabbit
(liquid, PBS, azide, affinity purified)
WB Mouse immunogen = synthetic peptide, deruvced from the mid region of human BACE 2 protein BACE 2 -
Calbiochem EMD Biosciences polyclonal
IgG
Rabbit
(liquid, antiserum)
IH Human immunogen = synthetic peptide corresp. to aa 44-59 of human BACE BACE -
Calbiochem EMD Biosciences polyclonal
IgG
Rabbit
(liquid, undiluted)
IB, IC, IP Human, Mouse, Rat immunogen = synthetic peptide, C G I R L P L R S G L G G A P L G L R L P R, corresp. to aa 24-45 of human proBACE1 recognizes the ~60 kDa proBACE1 protein -
Calbiochem EMD Biosciences polyclonal
IgG
Rabbit
(liquid, serum, no preserve)
IF, IH, IP, RIA, WB Human, Mouse, Rat immunogen = a synthetic peptide, C L R Q Q H D D F A D D I S L L K, corresp. to aa 485-501 of BACE1, coupled to KLH recognizes the immature and mature forms of BACE1 protein -
Calbiochem EMD Biosciences kit
Unknown Host
IF - - BACE activity -
Calbiochem EMD Biosciences polyclonal
IgG
Rabbit
(liquid, serum, no preserve)
IP, WB Human immunogen = synthetic peptide, E T D E E P E E P G R R G S F V E M V D-C, corresp. to aa 46-65 of human BACE recognizes the ~65 and ~75 kDa glycosylated from of BACE protein -
Calbiochem EMD Biosciences polyclonal
IgG
Rabbit
(liquid, serum, no preserve)
IP, WB Human immunogen = a synthetic peptide, C-I R L P L R S G L G G A P L G L R L P R, corresp. to aa 26-45 of human BACE recognizes the ~65 and ~75 kDa glycosylated froms of the BACE protein -
Calbiochem EMD Biosciences polyclonal
IgG
Rabbit
(liquid, PBS, azide, purified by ion exchange chromatography)
WB Human, Mouse immunogen = synthetic peptide corresp. to aa 485-501 (C L R Q Q H D D F A D D I S L L K) of human BACE 70 kDa BACE -
IBL polyclonal
Rabbit
(purified, PBS, BSA, azide, lyophilized)
IH Human, Mouse, Rat immunogen = synthetic peptide of a part of human BACE1, (R L P R E T D E E P E E P G R R) BACE 1 -
IBL kit
Unknown Host
ELISA Human, Mouse, Rat - BACE 1 -
IBL polyclonal
Rabbit
(lyophilized, affinity purified, PBS, BSA, azide)
IH, IP, WB Human, Mouse, Rat immunogen = synthetic peptide of C-terminal of human BACE1, (C L R Q Q H D D F A D D I S L L K) BACE 1 -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, PBS, azide, purified)
IH, WB Human, Mouse, Rat immunogen = synthetic peptide corresponding to aa near the N-terminus of human BACE 2 BACE2 -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, PBS, azide, affinity purified)
IH, WB Human, Mouse, Rat immunogen = synthetic peptide corresp. to aa44-59 of human BACE2 BACE2 -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, PBS, azide, affinity purified)
IF, IH, WB Human, Mouse immunogen = synthetic peptide corresp. to aa S28 detects endogenous levels of BACE protein -
Novus Biologicals monoclonal
IgGmix, κ
Mouse
(liquid, purified, no preservative)
WB Human immunogen = full length recombinant BACE1 BACE1 - beta-site APP-cleaving enzyme 1 -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, whole antiserum, azide)
ELISA, IH, WB Human immunogen = synthetic peptide corresp. to residues surrounding Ser498 of human BACE1 BACE1-beta-site APP-cleaving enzyme 1 [Ser498] -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, PBS, azide)
WB Human, Mouse, Rat immunogen = raised against a synthetic peptide (A P T P G P G T P A E R H A D G) corresp. to aa44 to 59 of human BACE2 BACE /Asp2 -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, PBS, whole antiserum, azide)
WB Human, Mouse, Rat immunogen = synthetic peptide corresp. to aa44-59 of human BACE2 recognizes an epitope within the N-terminal region of BACE2, a homologue of the beta-site APP cleaving enzyme (BACE) -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, PBS, azide, affinity purified)
IH Human immunogen = synthetic peptide corresp. to internal domain of human BACE1 BACE1 -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, PBS, azide, affinity purified)
IH Human immunogen = synthetic peptide near N-terminus (aa30-80) of human BACE1 -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, PBS, azide)
WB Human immunogen = raised against a peptide corresp. to aa496 to 511 of human BACE BACE /Asp2 -
Novus Biologicals polyclonal
Rabbit
(liquid, PBS, azide, affinity purified)
IH Human immunogen = synthetic peptide near N-terminus (aa30-80) of human BACE BACE1 -
Novus Biologicals polyclonal
Rabbit
(liquid, no preservative, protein A purified)
ELISA, WB Human immunogen = BACE1 (NP_620428.1, aa1-476) full-length human protein BACE1 -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, PBS, azide, affinity purified)
WB Human, Mouse, Rat immunogen = synthetic peptide: V S E I S G P F S T E D I A S N C, corresp. to aa441-457 of human BACE2 BACE 2 -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, PBS, azide, affinity purified)
WB Human immunogen = synthetic peptide: C P E V V N D E S S LV R H R W K, corresp. to aa503-518 of human BACE2 BACE 2 -
Novus Biologicals polyclonal
Mouse
(liquid, sera, no preservative)
ELISA, WB Human immunogen = partial recombinant BACE2 (NP_036237, aa306-396) BACE2 - beta-site APP-cleaving enzyme 2 -
Novus Biologicals polyclonal
Goat
(liquid, whole antisera, azide)
IH Human immunogen = synthetic peptide C L R Q Q H D D F A D D I S L L K corresp. to the C-terminal aa seq. 458-501 of human BACE BACE1 -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, PBS, azide, purified)
IH, WB Human, Mouse, Rat immunogen = synthetic peptide corresp. to aa near the N-terminus of human BACE 2 BACE /Asp2 (70 kDa) -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, PBS, azide, affinity purified)
IH, WB Human, Mouse, Rat immunogen = synthetic peptide corresp. to aa44-59 of human BACE2 BACE /Asp2 (aa44-59) -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, PBS, azide, affinity purified)
ELISA, IF, IH Human, Mouse immunogen = peptide made to the amino acid region S28 endogenous levels of BACE1 -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, PBS, azide, purified)
WB Human, Mouse, Rat immunogen = synthetic peptide, corresp. to aa485-501 of human BACE endogenous levels of BACE1 -
Novus Biologicals monoclonal
IgG mix, κ
Mouse
(liquid, no preservative, purified)
ELISA, IH, WB Human immunogen = BACE1 (AAH65492, aa22-502 a.a) full length recombinant protein with GST tag BACE1 -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, PBS, azide)
WB Human, Mouse immunogen = raised against a peptide corresp. to aa485 to 501 of human BACE BACE 1 -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, PBS, azide, purified)
WB Human immunogen = peptide corresp. to aa496-511 of human BACE2 BACE /Asp2 -
QED Bioscience polyclonal
IgG
Rabbit
(liquid, affinity purified, azide)
IB Human, Mouse, Rat immunogen = synthetic peptide corresp. to aa. 44-59 near the N-terminal of human BACE2 ~75 kDa BACE2 protein -
QED Bioscience polyclonal
IgG
Rabbit
(liquid, purified, PBS, azide)
IB Human immunogen = synthetic peptide correp. to aa. 496-511 near the C-terminal of human BACE2 ~75 kDa BACE2 protein -
QED Bioscience polyclonal
IgG
Rabbit
(liquid, purified, PBS, azide)
IB Human, Mouse immunogen = synthetic peptide corresp. to aa. 485-501 near the C-terminal of human BACE ~70 kDa BACE protein -
R&D Systems kit
Unknown Host
(extraction buffer, reaction buffer, 96 well microplate)
IF - immunogen = APPpeptide Y E V H H Q K L V using E D A N S D A B C Y L as the reporter system detects enzymatic activity of the α-secretase class of proteases associated withthe cleavage of APP -
R&D Systems polyclonal
IgG
Goat
(affinity purified, filtered, PBS, trehalose, lyophilized)
ELISA, WB Mouse immunogen = purified, NS0-derived recombinant mouse BACE-2, aa 63-462 recognizes mouse BACE-2 -
R&D Systems polyclonal
IgG
Sheep
(affinity purified, filtered, PBS, BSA, lyophilized, biotinylated)
WB Human immunogen = purified, NS0-derived recombinant human BACE-2, aa 63-466 recognizes human BACE-2; -
R&D Systems monoclonal
IgG1
Mouse
(liquid, PBS, azide, APC conj.)
FC Human   intended to identify and quantitate cells expressing cytoplasmic forms of the protein rhBACE-1 -
R&D Systems polyclonal
IgG2a
Sheep
(lyophilized, affinity purified, filtered, PBS, BSA)
ELISA, IH Human immunogen = E.coli derived recombinant human BACE-2 recognizes human BACE-2; -
Santa Cruz polyclonal
IgG
Goat
(purified, PBS, azide)
IH, WB Human, Mouse, Rat immunogen = peptide mapping within and internal region of human BACE2 BACE -
Santa Cruz polyclonal
IgG
Goat
(purified IgG, PBS, azide)
IH, WB Human immunogen = peptide mapping near the N-terminus of human BACE2 BACE2 -
Santa Cruz polyclonal
IgG
Goat
(purified, PBS, azide)
IH, WB Human, Mouse, Rat immunogen peptide mapping at the C-terminus of human BACE2 BACE -
Santa Cruz polyclonal
IgG
Rabbit
(purified, PBS, azide)
IH, IP, WB Human, Mouse, Rat immunogen = peptide mapping corr. to aa. 419-501 at the C-terminus of mouse BACE BACE -
Santa Cruz polyclonal
IgG1
Mouse
(purified, PBS, azide)
IF, IH, IP, WB Human, Mouse, Rat immunogen = full length of human BACE BACE -
Santa Cruz polyclonal
IgG
Goat
(purified, PBS, azide)
IH, WB Human, Mouse, Rat immunogen = peptide mapping within and internal region of human BACE2 BACE2 -
Santa Cruz polyclonal
IgG
Rabbit
(purified, PBS, azide, gelatin)
IF, IP, WB Human, Mouse, Rat immunogen = epitope corresp. to aa 429-518 of human BACE2 BACE2 -
Santa Cruz polyclonal
IgG
Goat
(purified, PBS, azide, gelatin; blocking peptide sc-10051P)
IF, WB Human, Mouse, Rat immunogen = epitope mapping at the C-terminus of human BACE2 BACE2 -
Santa Cruz monoclonal
IgG1
Mouse
(purified, PBS, azide)
FC, IF, IH, WB Human, Mouse immunogen = raised against the aa22-460 of human BACE BACE -
AnaSpec polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
IH, WB Human immunogen = a synthetic peptide corresponding to amino acids near the C-terminus of human BACE2 detects BACE2 -
AnaSpec polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide)
IH, WB Human, Mouse, Rat immunogen = a synthetic peptide corresponding to amino acids near the N-terminus of human BACE2 detects BACE2 -
AnaSpec polyclonal
IgG
Rabbit
(liquid, ion exchange purified, PBS, azide)
IC, WB Human, Mouse immunogen = a synthetic peptide corresponding to 17 amino acids at the C-terminus of human BACE detects BACE -
None monoclonal
Ig
Rabbit
(crude antiserum)
IH, IP, WB Human, Mouse, Rat immunogen = a peptide sequence C G I R L P L R S G L G G A P L G L R L P R, 22 aa of human proBACE1 proBACE1 Discontinued
BioLegend polyclonal
Ig
Rabbit
(liquid, antiserum)
IC, IP, WB Human, Mouse, Rat immunogen = a peptide sequence CLRQQHDD FADDISLLK, the C-terminal 17 amino acids of the human BACE1 recognises the mature and immature forms of BACE Available from BioLegend
None monoclonal
Ig
Guinea Pig
(crude antiserum)
IH, IP, WB Human, Mouse, Rat immunogen = a peptide sequence C L R Q Q H D D F A D D I S L L K , the C-terminal 17 aa of human BACE1 recognises the mature and immature forms of BACE Discontinued