The Antibodies database was archived in December 2022 and is no longer being updated. The Antibodies database is being supplanted by the AlzAntibodies database, which aims to provide detailed descriptions of selected antibodies.

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Antibodies

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	Name	Source	Clonality & Isotype	Host & Formulation	Method	Reactivity	Immunogen/ Epitope	Specificity	Availability
γ-secretase/ Presenilins From labs (7)
	PS-1 NTF	antibodies 95/23 and 98/1(Janetta Culvenor,Department of Pathology, The University of Melbourne, Victoria, Australia)used in paper by Runz, 2002	polyclonal	Rabbit	-	-	epitope at PS1, aa 1-20	PS1 in human neuroblastoma SH-SY5Y wild type and PS1 transfectants (SY5Y-PS1) as well as in mouse P19, in CHO-K1 and CHO-APP770 transfected cells, in rat cerebellar granule and hippocampal neurons, and astrocytes. 50 kDa and 30 kDa presumptive cleavage product in WB	-
	PS-1 NTF	anti-PS1 CTF29414(C. Elle,Center for Molecular Biology Heidelberg (ZMBH), University of Heidelberg, INF 282, D-69120 Heidelberg)used in paper by Runz, 2002	polyclonal		-	-			-
	PS-1	PS1-3027(Christian Haass,Adolf Butenandt Institute, University of Munich)used in paper by Steiner, 2002	polyclonal		-	-	loop domain (aa 263-407) of PS-1	loop domain of PS-1	-
	PS-1	PS1-2953(Christian Haass,Adolf Butenandt Institute, University of Munich)	polyclonal		-	-	N-terminus (aa 2-81) of PS-1	N terminus of PS-1	-
	PS-2	PS2-3711(Christian Haass,Adolf Butenandt Institute, University of Munich)used in paper by Steiner, 2002	polyclonal		-	-	loop domain (aa 297-356) of PS-2	loop domain of PS-2	-
	PS-2	PS2-2972(Christian Haass,Adolf Butenandt Institute, University of Munich)used in paper by Steiner, 2002paper by Esler, 2002	polyclonal		-	-	N terminus of PS-2	N terminus of PS-2	-
	PS-2	PS1-BIH.F5C(Christian Haass,Adolf Butenandt Institute, University of Munich)used in paper by Steiner, 2002	monoclonal		-	-	fusion protein, C-terminal (aa 297-356)	C terminus of PS-2	-
γ-secretase/ Presenilins From manufacturers (93)
	Presenilin-1 [S182]	Accurate	polyclonal	Goat	-	-	immunogen = 14-33 aa of N-Terminus, extracellular region	S182 peptide	-
	Presenilin-2	Accurate	polyclonal	Goat	-	Human		Presenilin 2	-
	Presenilin-1	Biodesign Meridian LifeScience	polyclonal	Goat (neat, liquid, azide)	-	Human	immunogen = synthetic peptide, 14-33 aa of N-Terminus	aa 14-33 of Presenilin-1	-
	Presenilin-2	Biodesign Meridian LifeScience	polyclonal	Goat (neat, liquid, azide)	-	Human	immunogen = synthetic peptide, 31-47 aa of N-Terminus	aa 31-47 of Presenilin-2	-
	PS-2 NTF	R&D Systems	polyclonal IgG	Goat (affinity purified, PBS, filtered, lyophilized)	-	Human	immunogen = purified E.Coli-derived recombinant human PS-2 NTF (aa 1-80)	hPS-2 NTF; < 1% cross with rhPS-1 NTF (aa 1-80) and rhPS-2 CTF (aa 308-388)	-
	PS-1 NTF	R&D Systems	polyclonal IgG	Goat (affinity purified, Biotin, PBS, filtered, lyophilized)	-	Human	immunogen = purified E.Coli-derived recombinant human PS-1 NTF (aa 1-80)	hPS-1 NTF; in WB < 1% cross with rhPS-1 CTF (aa 298-407) and rhPS-2 NTF (aa 1-80)	-
	Presenilin-1	Biotrend	polyclonal	Goat (liquid, Ig fract, PBS, azide)	-	-	immunogen = synthetic peptide corr. to aa 14 - 33 of N-Terminus	Presenilin-1 N-terminal residues 14-33	-
	PS-1 CTF	R&D Systems	polyclonal IgG	Goat (affinity purified, Biotin, PBS, filtered, lyophilized)	-	Human	immunogen = purified E.Coli-derived recombinant human PS-1 CTF (aa 298-407)	hPS-1 CTF; < 1% cross with rhPS-1 NTF (aa 1-80) and rhPS-2 CTF (aa 322-388) in WB	-
	PS-1 NTF	R&D Systems	polyclonal IgG	Goat (affinity purified, PBS, filtered, lyophilized)	-	Human	immunogen = purified E.Coli-derived recombinant human PS-1 NTF (aa 1-80)	rhPS-1 NTF; no cross with rhPS-1 CTF (aa 298-407) or rhPS-2 NTF (aa 1-80)	-
	PS-2 CTF	R&D Systems	polyclonal IgG	Goat (affinity purified, PBS, filtered, lyophilized)	-	Human	immunogen = purified E.Coli-derived recombinant human PS-2 CTF (aa 322-388)	rhPS-2 CTF; < 1% cross with rhPS-1 NTF (aa 1-80), rhPS-1 CTF (aa 298-407) or rhPS-2 NTF (aa 1-80)	-
	Presenilin-2	AbD Serotec	polyclonal	Goat (liquid, serum, azide)	-	Human	immunogen = synthetic peptide corr. to aa 31-47 of Presenilin-2	recognizes Presenilin-2, binding to neurons in both normal and Alzheimer disease brain	-
	PS-1	A B R - Thermo Scientific	polyclonal IgY	Chicken (purified, PBS, BSA, azide)	-	Human, Mouse, Rat	immunogen = synthetic peptides, (aa 311-322) and (aa 342-353)	PS-1	-
	PS-1 (APS 11)	A B R - Thermo Scientific	monoclonal IgG1	Mouse (protein-G, PBS, BSA, azide)	-	Human, Mouse, Rat, Primate (various)	immunogen = synthetic peptide, N-terminal (aa 21-34)	PS-1; no cross with PS-2	-
	PS-1 (APS 18)	A B R - Thermo Scientific	monoclonal IgG1	Mouse (protein-G, PBS, BSA, azide)	-	Human, Mouse, Rat, Primate (various)	immunogen = synthetic peptide, C-terminal (aa 313-334)	PS-1; no cross with PS-2	-
	PS-2 (APS 21)	A B R - Thermo Scientific	monoclonal IgG1	Mouse (protein-G, PBS, BSA, azide)	-	Human, Rat, Primate (various)	immunogen = synthetic peptide, (aa 31-45)	PS-2; no cross with PS-1	-
	PS-2 (APS 26)	A B R - Thermo Scientific	monoclonal IgG1	Mouse (protein-G, PBS, BSA, azide)	-	Human, Mouse, Rat, Primate (various)	immunogen = synthetic peptide, C terminal (aa 317-334)	PS-2; no cross with PS-1	-
	Ubiquilin	A B R - Thermo Scientific	polyclonal IgG	Rabbit (IgG, epitope affinity purified IgG, PBS, BSA, azide)	-	Hamster	immunogen = synthetic peptide corresponds to aa 2-18 of mouse ubiquilin	Ubiquilin from hamster cells	-
	Nicastrin	Cell Signaling	polyclonal	Rabbit (affinity purified)	-	Human, Monkey, Mouse, Rat	immunogen = synthetic peptide corr. to C-terminus of human Nicastrin, conj. to KLH	endogenous levels of Nicastrin	-
	Nicastrin	Abcam	polyclonal IgG	Rabbit (liquid, affinity purified)	-	Human, Mouse	immunogen = synthetic peptide, conj. to KLH, corr. to N-terminal aa 103-124 of nicastrin	~85 kDa nicastrin	-
	Nicastrin	Biodesign Meridian LifeScience	polyclonal IgG	Rabbit (liquid, protein-A purified, PBS, no preservative)	-	Human	immunogen = synthetic peptide corr. to aa residues 689-709 at C-terminus of nicastrin	reacts with nicastrin protein	-
	APH-1	Autogen Bioclear	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human, Mouse, Rat	immunogen = peptide mapping within an internal region of APH-1 of human origin.	18 kDa Aph-1	-
	APH-1	Autogen Bioclear	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	C. elegans	immunogen = peptide mapping within an internal region of APH-1 of C.Elegans origin.	Aph-1	-
	APH-1	Autogen Bioclear	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	C. elegans	immunogen = peptide mapping at the C-terminus of APH-1 of C.Elegans origin.	Aph-1	-
	Nicastrin	Autogen Bioclear	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human, Mouse, Rat	immunogen = peptide mapping near the N-terminus of Nicastrin of human origin.	120 and 145 kDa Nicastrin	-
	Nicastrin	Autogen Bioclear	polyclonal IgG	Rabbit (liquid, PBS, azide, gelatin, affinity purified)	-	Human, Mouse, Rat	immunogen = epitope corresp. to aa 1-300 at the N-terminus of Nicastrin of human origin.	120 and 145 kDa Nicastrin	-
	PEN-2	Autogen Bioclear	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human	immunogen = peptide mapping at the N-terminus of PEN-2 of human origin.	PEN-2	-
	PEN-2	Autogen Bioclear	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human	immunogen = peptide mapping within an internal region of PEN-2 of human origin.	PEN-2	-
	PEN-2	Autogen Bioclear	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human, C. elegans	immunogen = peptide mapping within an internal region of PEN-2 of C. elegans origin.	PEN-2	-
	PEN-2	Autogen Bioclear	polyclonal IgG	Rabbit (liquid, PBS, azide, gelatin, affinity purified)	-	Human, Mouse, Rat	immunogen = peptide mapping corresp. aa to 1-101, representing full length PEN-2 of human origin.	PEN-2	-
	Ubiquilin1 /PLIC-1	Autogen Bioclear	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human, Mouse, Rat	immunogen = peptide mapping near the C-terminus of PLIC-1 of human origin.	Ubiquilin1/PLIC-1	-
	Ubiquilin1 /PLIC-1	Autogen Bioclear	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human	immunogen = peptide mapping within an internal region of PLIC-1 of human origin.	Ubiquilin1/PLIC-1	-
	Ubiquilin1 /PLIC-1	Autogen Bioclear	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Mouse, Rat	immunogen = peptide mapping within an internal region of PLIC-1 of human origin.	Ubiquilin1/PLIC-1	-
	Ubiquilin2 /PLIC-2	Autogen Bioclear	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human, Mouse, Rat	immunogen = peptide mapping near the C-terminus of PLIC-2 of human origin.	Ubiquilin2/PLIC-2	-
	Ubiquilin2 /PLIC-2	Autogen Bioclear	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human	immunogen = peptide mapping within an internal region of PLIC-2 of human origin.	Ubiquilin2/PLIC-2	-
	Ubiquilin2 /PLIC-2	Autogen Bioclear	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Mouse, Rat	immunogen = peptide mapping within an internal region of PLIC-2 of mouse origin.	Ubiquilin2/PLIC-2	-
	Nicastrin	Bachem	kit	Rabbit	-	-	Immunogen = aa 1-17 of human nicastrin	-	-
	Nicastrin	Bachem	polyclonal	Rabbit (purified antiserum)	-	-	Immunogen = aa 1-17 of human nicastrin	-	-
	Nicastrin	Bachem	polyclonal	Rabbit (diluted antiserum)	-	-	Immunogen = aa 1-17 of human nicastrin	-	-
	Nicastrin	Bachem	polyclonal	Rabbit (undiluted antiserum)	-	-	Immunogen = aa 1-17 of human nicastrin	-	-
	Nicastrin	Bachem	kit	Rabbit	-	-	Immunogen = aa 1-17 of human nicastrin	-	-
	Nicastrin	Bachem	kit	Rabbit (high sensitivity)	-	-	Immunogen = aa 656-676 of human nicastrin	-	-
	Nicastrin	Bachem	kit	Rabbit (high sensitivity)	-	-	Immunogen = aa 1-17 of human nicastrin	-	-
	Nicastrin	Bachem	kit	Rabbit	-	-	Immunogen = aa 656-676 of human nicastrin	-	-
	Nicastrin	Bachem	kit	Rabbit	-	-	Immunogen = aa 656-676 of human nicastrin	-	-
	Nicastrin	Bachem	kit IgG	Rabbit (purified antiserum)	-	-	Immunogen = aa 656-676 of human nicastrin	-	-
	Nicastrin	Bachem	polyclonal	Rabbit (undiluted antiserum)	-	-	Immunogen = aa 656-676 of human nicastrin	-	-
	Nicastrin	Bachem	polyclonal	Rabbit (diluted antiserum)	-	-	Immunogen = aa 656-676 of human nicastrin	-	-
	Nicastrin	Immunologicals Direct AbD Serotec	polyclonal IgG	Rabbit (liquid, purified, PBS, no carrier, no preservative)	-	Human	immunogen = aa 698-709 of nicastrin	nicastrin protein	-
	Nicastrin	Calbiochem EMD Biosciences	polyclonal IgG	Rabbit (liquid, undiluted serum, conj. with KLH)	-	Human, Mouse	immunogen = synthetic peptide corr. to aa residues 689-709 at C-terminus of nicastrin	both the latent and active forms of Nicastrin	-
	Nicastrin	None	polyclonal IgG	Rabbit (liquid, purified, PBS, no carrier, no preservative)	-	Human	immunogen = aa 698-709 of nicastrin	nicastrin protein	Discontinued
	Nicastrin	Calbiochem EMD Biosciences	polyclonal IgG	Rabbit (liquid, undiluted serum, conj. with KLH)	-	Human, Mouse	immunogen = synthetic peptide corr. to aa residues 62-93 at N-terminus of nicastrin	both the letent and active forms of Nicastrin	-
	Nicastrin	Insight Biotechnology	polyclonal IgG	Rabbit (liquid, PBS, azide, gelatin, affinity purified)	-	Human, Mouse, Rat	immunogen = epitope corresp. to aa 1-300 at the N-terminus of Nicastrin of human origin.	120 and 145 kDa Nicastrin	-
	APH-1	Insight Biotechnology	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human, Mouse, Rat	immunogen = peptide mapping within an internal region of APH-1 of human origin.	18 kDa Aph-1	-
	APH-1	Insight Biotechnology	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	C. elegans	immunogen = peptide mapping within an internal region of APH-1 of C.Elegans origin.	Aph-1	-
	APH-1	Insight Biotechnology	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	C. elegans	immunogen = peptide mapping at the C-terminus of APH-1 of C.Elegans origin.	Aph-1	-
	Nicastrin	Insight Biotechnology	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human, Mouse, Rat	immunogen = peptide mapping near the N-terminus of Nicastrin of human origin.	120 and 145 kDa Nicastrin	-
	PEN-2	Insight Biotechnology	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human	immunogen = peptide mapping within an internal region of PEN-2 of human origin.	PEN-2	-
	PEN-2	Insight Biotechnology	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human, C. elegans	immunogen = peptide mapping within an internal region of PEN-2 of C. elegans origin.	PEN-2	-
	Ubiquilin1 /PLIC-1	Insight Biotechnology	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human, Mouse, Rat	immunogen = peptide mapping near the C-terminus of PLIC-1 of human origin.	Ubiquilin1/PLIC-1	-
	Ubiquilin1 /PLIC-1	Insight Biotechnology	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human	immunogen = peptide mapping within an internal region of PLIC-1 of human origin.	Ubiquilin1/PLIC-1	-
	Ubiquilin1 /PLIC-1	Insight Biotechnology	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Mouse, Rat	immunogen = peptide mapping within an internal region of PLIC-1 of human origin.	Ubiquilin1/PLIC-1	-
	Ubiquilin2 /PLIC-2	Insight Biotechnology	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human, Mouse, Rat	immunogen = peptide mapping near the C-terminus of PLIC-2 of human origin.	Ubiquilin2/PLIC-2	-
	Ubiquilin2 /PLIC-2	Insight Biotechnology	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human	immunogen = peptide mapping within an internal region of PLIC-2 of human origin.	Ubiquilin2/PLIC-2	-
	Ubiquilin2 /PLIC-2	Insight Biotechnology	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Mouse, Rat	immunogen = peptide mapping within an internal region of PLIC-2 of mouse origin.	Ubiquilin2/PLIC-2	-
	Nicastrin	Interchim	polyclonal	Rabbit (antiserum)	-	-	-	-	-
	Ubiquilin1	Interchim	polyclonal	Rabbit	-	-	-	-	-
	Ubiquilin1	Interchim	polyclonal	Rabbit	-	-	-	-	-
	PEN2	Interchim	polyclonal	Rabbit	-	-	-	-	-
	PEN2, C-Term	Interchim	polyclonal	Rabbit	-	-	-	-	-
	PEN2, N-Term	Interchim	polyclonal	Rabbit	-	-	-	-	-
	PEN2, Center	Interchim	polyclonal	Rabbit	-	-	-	-	-
	Presenilin-2	Accurate	polyclonal	Goat	-	Human		Presenilin 2	-
	Presenilin-2	Accurate	polyclonal	Goat (serum)	-	Human		Presenilin 2	-
	Presenilin-1	A D I	monoclonal	Rat (antiserum, ascites, unpurified)	-	Human, Mouse, Rat	immunogen = GST-human PS1 fusion protein (aa 21-80)	Presenilin-1	-
	Presenilin 1	Acris Antibodies	monoclonal	Rat (antiserum, ascites, unpurified)	-	Human, Mouse, Rat	immunogen = GST-human PS1 fusion protein (aa 21-80)	Presenilin-1	-
	Presenilin 1	Acris Antibodies	polyclonal	Rabbit (unpurified antiserum)	-	Human, Mouse, Rat, Xenopus	immunogen = a 15 mer peptide (PS11-P) locating to the large hydrophilic loop of human or mouse Presenilin-1	Presenilin-1	-
	Presenilin 1	Acris Antibodies	polyclonal IgG	Rabbit (affinity purified with PBS, BSA and merthiolate)	-	Human, Mouse, Rat, Xenopus	immunogen = a 15 mer peptide (PS11-P) locating to the large hydrophilic loop of human or mouse Presenilin-1	Presenilin-1	-
	PEN2	Abcam	polyclonal IgG	Rabbit (liquid, PBS, azide, affinity purified)	-	Human, Mouse	immunogen = synthetic peptide derived from within residues 1-100 of human PEN2, conj. to KLH	PEN2 (12kDa); higher mwt bands also detected at ~50 and 100kDa due to portion of Pen2 bound to components of gamma secretase complex	-
	PEN2	Abcam	polyclonal IgG	Rabbit (liquid, whole serum)	-	Human	immunogen = synthetic peptide (F Q I Y R P R W G A L G D Y L S F T I P L G T P) of human PEN2	Pen-2 protein	-
	Ubiquilin	Abcam	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, BSA, azide)	-	Hamster, Mouse	immunogen = synthetic peptide, A E S A E S G G P P G A Q D S A A, corr. to aa 2-18 of mouse ubiquilin	~63 kDa ubiquilin	-
	APH 1b	Abcam	polyclonal IgG	Rabbit (liquid, PBS, glycerol, BSA, azide, affinity purified)	-	Human	immunogen = synthetic peptide from loop region of human Aph-1b; Epitope seq. C K L L K K A S E G L K S I N P G E T A P S M R	Aph 1b	-
	APH 1b	Abcam	polyclonal IgG	Rabbit (liquid, PBS, BSA, glycerol, azide, affinity purified)	-	Human	immunogen = synthetic peptide containing the C- terminal seq. of human Aph 1b; Epitope seq. C Q D K N F L L Y N Q R S R Q D K N F L L Y N Q R S R	Aph-1b	-
	APH1a	Abcam	polyclonal IgG	Rabbit (liquid, PBS, BSA, azide, affinity purified)	-	Human, Mouse, Rat	immunogen = synthetic peptide derived from residues 50-150 of human APH1a	recognises both isoforms of APH1a (encoded on chromosome 1)	-
	APH1a	Abcam	polyclonal IgG	Rabbit (liquid, PBS, glycerol, PBS, azide, affinity purified)	-	Human, Mouse	immunogen = synthetic peptide (C R R Q E D S R V M V Y S A L R I P P E D corresp. to C-terminal domain of the long isoform of aa 245-265 of human APH1a, conj. to KLH	Anterior Pharynx Defective 1 (APH1a)	-
	Nicastrin	Abcam	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, BSA, azide)	-	Human, Mouse	immunogen = synthetic peptide (I N A K A D V L F I A P R E P G A V S Y corr. to C-terminal aa 688-708 from human nicastrin	~110 kDa nicastrin	-
	APH1	ABGENT	polyclonal	Rabbit (liquid, PBS, azide, protein G purified)	-	Human	immunogen = synthetic peptide, 10-30 aa, at the N-term of first 110 aa of human APH1, conj. to KLH	Aph1	-
	APH1	ABGENT	polyclonal	Rabbit (liquid, PBS, azide, protein G purified)	-	Human	immunogen synthetic peptide, 10-30 aa, at the C-term of last 50 aa of human APH1	Aph1	-
	PEN2	ABGENT	polyclonal	Rabbit (liquid, PBS, azide, protien G purified)	-	Human	immunogen = synthetic peptide, 10-30 aa, at the N-term of first 50 aa of human PEN2, conj. to KLH	Pen2	-
	PEN2	ABGENT	polyclonal	Rabbit (liquid, PBS, azide, protein G purified)	-	Human	immunogen = synthetic peptide, 10-30 aa, at the N-term of first 60 aa of human PEN2	Pen2	-
	PEN2	ABGENT	polyclonal	Rabbit (liquid, PBS, azide, protein G purified)	-	Human	immunogen = synthetic peptide (10-30 aa) at the N-term of first 100 aa of human PEN2, conj. to KLH	Pen2	-
	PEN2	ABGENT	polyclonal	Rabbit (liquid, PBS, azide)	-	Human	immunogen = synthetic peptide selected from the N-terminal region of human PEN2, conj. to KLH	Pen2	-
	PEN2	ABGENT	polyclonal	Rabbit (liquid, Ig fraction, PBS, azide)	-	Human	immunogen = synthetic peptide selected from the center region of human PEN2, conj. to KLH	Pen2	-
	Ubiquilin1	ABGENT	polyclonal	Rabbit (liquid, PBS, azide, protein G purified)	-	Human, Mouse	immunogen = synthetic peptide (10-30 aa in length) at the N-term of first 100 aa of human Ubiquilin1, conj. to KLH	ubiquilin1	-