|
|
Accurate |
polyclonal
|
Goat
|
- |
- |
immunogen = 14-33 aa of N-Terminus, extracellular region |
S182 peptide |
- |
|
|
Accurate |
polyclonal
|
Goat
|
IH, ELISA |
Human |
|
Presenilin 2 |
- |
|
|
Biodesign Meridian LifeScience |
polyclonal
|
Goat
(neat, liquid, azide) |
IH, WB, ELISA |
Human |
immunogen = synthetic peptide, 14-33 aa of N-Terminus |
aa 14-33 of Presenilin-1 |
- |
|
|
Biodesign Meridian LifeScience |
polyclonal
|
Goat
(neat, liquid, azide) |
IH, WB, ELISA |
Human |
immunogen = synthetic peptide, 31-47 aa of N-Terminus |
aa 31-47 of Presenilin-2 |
- |
|
|
R&D Systems |
polyclonal
IgG |
Goat
(affinity purified, PBS, filtered, lyophilized) |
IH, WB, ELISA |
Human |
immunogen = purified E.Coli-derived recombinant human PS-2 NTF (aa 1-80) |
hPS-2 NTF; < 1% cross with rhPS-1 NTF (aa 1-80) and rhPS-2 CTF (aa 308-388) |
- |
|
|
R&D Systems |
polyclonal
IgG |
Goat
(affinity purified, Biotin, PBS, filtered, lyophilized) |
WB |
Human |
immunogen = purified E.Coli-derived recombinant human PS-1 NTF (aa 1-80) |
hPS-1 NTF; in WB < 1% cross with rhPS-1 CTF (aa 298-407) and rhPS-2 NTF (aa 1-80) |
- |
|
|
Biotrend |
polyclonal
|
Goat
(liquid, Ig fract, PBS, azide) |
IH, ELISA |
- |
immunogen = synthetic peptide corr. to aa 14 - 33 of N-Terminus |
Presenilin-1 N-terminal residues 14-33 |
- |
|
|
R&D Systems |
polyclonal
IgG |
Goat
(affinity purified, Biotin, PBS, filtered, lyophilized) |
IH, WB |
Human |
immunogen = purified E.Coli-derived recombinant human PS-1 CTF (aa 298-407) |
hPS-1 CTF; < 1% cross with rhPS-1 NTF (aa 1-80) and rhPS-2 CTF (aa 322-388) in WB |
- |
|
|
R&D Systems |
polyclonal
IgG |
Goat
(affinity purified, PBS, filtered, lyophilized) |
IH, WB, ELISA |
Human |
immunogen = purified E.Coli-derived recombinant human PS-1 NTF (aa 1-80) |
rhPS-1 NTF; no cross with rhPS-1 CTF (aa 298-407) or rhPS-2 NTF (aa 1-80) |
- |
|
|
R&D Systems |
polyclonal
IgG |
Goat
(affinity purified, PBS, filtered, lyophilized) |
IH, WB, ELISA |
Human |
immunogen = purified E.Coli-derived recombinant human PS-2 CTF (aa 322-388) |
rhPS-2 CTF; < 1% cross with rhPS-1 NTF (aa 1-80), rhPS-1 CTF (aa 298-407) or rhPS-2 NTF (aa 1-80) |
- |
|
|
AbD Serotec |
polyclonal
|
Goat
(liquid, serum, azide) |
IH |
Human |
immunogen = synthetic peptide corr. to aa 31-47 of Presenilin-2 |
recognizes Presenilin-2, binding to neurons in both normal and Alzheimer disease brain |
- |
|
|
A B R - Thermo Scientific |
polyclonal
IgY |
Chicken
(purified, PBS, BSA, azide) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptides, (aa 311-322) and (aa 342-353) |
PS-1 |
- |
|
|
A B R - Thermo Scientific |
monoclonal
IgG1 |
Mouse
(protein-G, PBS, BSA, azide) |
IF, IH, WB, ELISA |
Human, Mouse, Rat, Primate (various) |
immunogen = synthetic peptide, N-terminal (aa 21-34) |
PS-1; no cross with PS-2 |
- |
|
|
A B R - Thermo Scientific |
monoclonal
IgG1 |
Mouse
(protein-G, PBS, BSA, azide) |
IF, WB, ELISA |
Human, Mouse, Rat, Primate (various) |
immunogen = synthetic peptide, C-terminal (aa 313-334) |
PS-1; no cross with PS-2 |
- |
|
|
A B R - Thermo Scientific |
monoclonal
IgG1 |
Mouse
(protein-G, PBS, BSA, azide) |
IF, WB, ELISA |
Human, Rat, Primate (various) |
immunogen = synthetic peptide, (aa 31-45) |
PS-2; no cross with PS-1 |
- |
|
|
A B R - Thermo Scientific |
monoclonal
IgG1 |
Mouse
(protein-G, PBS, BSA, azide) |
IF, WB, ELISA |
Human, Mouse, Rat, Primate (various) |
immunogen = synthetic peptide, C terminal (aa 317-334) |
PS-2; no cross with PS-1 |
- |
|
|
A B R - Thermo Scientific |
polyclonal
IgG |
Rabbit
(IgG, epitope affinity purified IgG, PBS, BSA, azide) |
WB |
Hamster |
immunogen = synthetic peptide corresponds to aa 2-18 of mouse ubiquilin |
Ubiquilin from hamster cells |
- |
|
|
Cell Signaling |
polyclonal
|
Rabbit
(affinity purified) |
WB |
Human, Monkey, Mouse, Rat |
immunogen = synthetic peptide corr. to C-terminus of human Nicastrin, conj. to KLH |
endogenous levels of Nicastrin |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, affinity purified) |
IC, IF, IP, WB |
Human, Mouse |
immunogen = synthetic peptide, conj. to KLH, corr. to N-terminal aa 103-124 of nicastrin |
~85 kDa nicastrin |
- |
|
|
Biodesign Meridian LifeScience |
polyclonal
IgG |
Rabbit
(liquid, protein-A purified, PBS, no preservative) |
IP, WB |
Human |
immunogen = synthetic peptide corr. to aa residues 689-709 at C-terminus of nicastrin |
reacts with nicastrin protein |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Human, Mouse, Rat |
immunogen = peptide mapping within an internal region of APH-1 of human origin. |
18 kDa Aph-1 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
C. elegans |
immunogen = peptide mapping within an internal region of APH-1 of C.Elegans origin. |
Aph-1 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
C. elegans |
immunogen = peptide mapping at the C-terminus of APH-1 of C.Elegans origin. |
Aph-1 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, IP, WB |
Human, Mouse, Rat |
immunogen = peptide mapping near the N-terminus of Nicastrin of human origin. |
120 and 145 kDa Nicastrin |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Rabbit
(liquid, PBS, azide, gelatin, affinity purified) |
IF, IP, WB |
Human, Mouse, Rat |
immunogen = epitope corresp. to aa 1-300 at the N-terminus of Nicastrin of human origin. |
120 and 145 kDa Nicastrin |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Human |
immunogen = peptide mapping at the N-terminus of PEN-2 of human origin. |
PEN-2 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Human |
immunogen = peptide mapping within an internal region of PEN-2 of human origin. |
PEN-2 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Human, C. elegans |
immunogen = peptide mapping within an internal region of PEN-2 of C. elegans origin. |
PEN-2 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Rabbit
(liquid, PBS, azide, gelatin, affinity purified) |
IF, IP, WB |
Human, Mouse, Rat |
immunogen = peptide mapping corresp. aa to 1-101, representing full length PEN-2 of human origin. |
PEN-2 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Human, Mouse, Rat |
immunogen = peptide mapping near the C-terminus of PLIC-1 of human origin. |
Ubiquilin1/PLIC-1 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Human |
immunogen = peptide mapping within an internal region of PLIC-1 of human origin. |
Ubiquilin1/PLIC-1 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Mouse, Rat |
immunogen = peptide mapping within an internal region of PLIC-1 of human origin. |
Ubiquilin1/PLIC-1 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Human, Mouse, Rat |
immunogen = peptide mapping near the C-terminus of PLIC-2 of human origin. |
Ubiquilin2/PLIC-2 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Human |
immunogen = peptide mapping within an internal region of PLIC-2 of human origin. |
Ubiquilin2/PLIC-2 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Mouse, Rat |
immunogen = peptide mapping within an internal region of PLIC-2 of mouse origin. |
Ubiquilin2/PLIC-2 |
- |
|
|
Bachem |
kit
|
Rabbit
|
IF |
- |
Immunogen = aa 1-17 of human nicastrin |
- |
- |
|
|
Bachem |
polyclonal
|
Rabbit
(purified antiserum) |
- |
- |
Immunogen = aa 1-17 of human nicastrin |
- |
- |
|
|
Bachem |
polyclonal
|
Rabbit
(diluted antiserum) |
RIA |
- |
Immunogen = aa 1-17 of human nicastrin |
- |
- |
|
|
Bachem |
polyclonal
|
Rabbit
(undiluted antiserum) |
IH |
- |
Immunogen = aa 1-17 of human nicastrin |
- |
- |
|
|
Bachem |
kit
|
Rabbit
|
RIA |
- |
Immunogen = aa 1-17 of human nicastrin |
- |
- |
|
|
Bachem |
kit
|
Rabbit
(high sensitivity) |
ELISA |
- |
Immunogen = aa 656-676 of human nicastrin |
- |
- |
|
|
Bachem |
kit
|
Rabbit
(high sensitivity) |
ELISA |
- |
Immunogen = aa 1-17 of human nicastrin |
- |
- |
|
|
Bachem |
kit
|
Rabbit
|
IF |
- |
Immunogen = aa 656-676 of human nicastrin |
- |
- |
|
|
Bachem |
kit
|
Rabbit
|
RIA |
- |
Immunogen = aa 656-676 of human nicastrin |
- |
- |
|
|
Bachem |
kit
IgG |
Rabbit
(purified antiserum) |
- |
- |
Immunogen = aa 656-676 of human nicastrin |
- |
- |
|
|
Bachem |
polyclonal
|
Rabbit
(undiluted antiserum) |
IH |
- |
Immunogen = aa 656-676 of human nicastrin |
- |
- |
|
|
Bachem |
polyclonal
|
Rabbit
(diluted antiserum) |
RIA |
- |
Immunogen = aa 656-676 of human nicastrin |
- |
- |
|
|
Immunologicals Direct AbD Serotec |
polyclonal
IgG |
Rabbit
(liquid, purified, PBS, no carrier, no preservative) |
IP, WB |
Human |
immunogen = aa 698-709 of nicastrin |
nicastrin protein |
- |
|
|
Calbiochem EMD Biosciences |
polyclonal
IgG |
Rabbit
(liquid, undiluted serum, conj. with KLH) |
IB, IP, RIA |
Human, Mouse |
immunogen = synthetic peptide corr. to aa residues 689-709 at C-terminus of nicastrin |
both the latent and active forms of Nicastrin |
- |
|
|
Calbiochem EMD Biosciences |
polyclonal
IgG |
Rabbit
(liquid, undiluted serum, conj. with KLH) |
IB, IF, IP |
Human, Mouse |
immunogen = synthetic peptide corr. to aa residues 62-93 at N-terminus of nicastrin |
both the letent and active forms of Nicastrin |
- |
|
|
Insight Biotechnology |
polyclonal
IgG |
Rabbit
(liquid, PBS, azide, gelatin, affinity purified) |
IF, IP, WB |
Human, Mouse, Rat |
immunogen = epitope corresp. to aa 1-300 at the N-terminus of Nicastrin of human origin. |
120 and 145 kDa Nicastrin |
- |
|
|
Insight Biotechnology |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Human, Mouse, Rat |
immunogen = peptide mapping within an internal region of APH-1 of human origin. |
18 kDa Aph-1 |
- |
|
|
Insight Biotechnology |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
C. elegans |
immunogen = peptide mapping within an internal region of APH-1 of C.Elegans origin. |
Aph-1 |
- |
|
|
Insight Biotechnology |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
C. elegans |
immunogen = peptide mapping at the C-terminus of APH-1 of C.Elegans origin. |
Aph-1 |
- |
|
|
Insight Biotechnology |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, IP, WB |
Human, Mouse, Rat |
immunogen = peptide mapping near the N-terminus of Nicastrin of human origin. |
120 and 145 kDa Nicastrin |
- |
|
|
Insight Biotechnology |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Human |
immunogen = peptide mapping within an internal region of PEN-2 of human origin. |
PEN-2 |
- |
|
|
Insight Biotechnology |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Human, C. elegans |
immunogen = peptide mapping within an internal region of PEN-2 of C. elegans origin. |
PEN-2 |
- |
|
|
Insight Biotechnology |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Human, Mouse, Rat |
immunogen = peptide mapping near the C-terminus of PLIC-1 of human origin. |
Ubiquilin1/PLIC-1 |
- |
|
|
Insight Biotechnology |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Human |
immunogen = peptide mapping within an internal region of PLIC-1 of human origin. |
Ubiquilin1/PLIC-1 |
- |
|
|
Insight Biotechnology |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Mouse, Rat |
immunogen = peptide mapping within an internal region of PLIC-1 of human origin. |
Ubiquilin1/PLIC-1 |
- |
|
|
Insight Biotechnology |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Human, Mouse, Rat |
immunogen = peptide mapping near the C-terminus of PLIC-2 of human origin. |
Ubiquilin2/PLIC-2 |
- |
|
|
Insight Biotechnology |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Human |
immunogen = peptide mapping within an internal region of PLIC-2 of human origin. |
Ubiquilin2/PLIC-2 |
- |
|
|
Insight Biotechnology |
polyclonal
IgG |
Goat
(liquid, PBS, azide, gelatin, affinity purified) |
IF, WB |
Mouse, Rat |
immunogen = peptide mapping within an internal region of PLIC-2 of mouse origin. |
Ubiquilin2/PLIC-2 |
- |
|
|
Interchim |
polyclonal
|
Rabbit
(antiserum) |
- |
- |
- |
- |
- |
|
|
Interchim |
polyclonal
|
Rabbit
|
- |
- |
- |
- |
- |
|
|
Interchim |
polyclonal
|
Rabbit
|
- |
- |
- |
- |
- |
|
|
Interchim |
polyclonal
|
Rabbit
|
- |
- |
- |
- |
- |
|
|
Interchim |
polyclonal
|
Rabbit
|
- |
- |
- |
- |
- |
|
|
Interchim |
polyclonal
|
Rabbit
|
- |
- |
- |
- |
- |
|
|
Interchim |
polyclonal
|
Rabbit
|
- |
- |
- |
- |
- |
|
|
Accurate |
polyclonal
|
Goat
|
- |
Human |
|
Presenilin 2 |
- |
|
|
Accurate |
polyclonal
|
Goat
(serum) |
ELISA, IH |
Human |
|
Presenilin 2 |
- |
|
|
A D I |
monoclonal
|
Rat
(antiserum, ascites, unpurified) |
ELISA, IF, IH, IP, WB |
Human, Mouse, Rat |
immunogen = GST-human PS1 fusion protein (aa 21-80) |
Presenilin-1 |
- |
|
|
Acris Antibodies |
monoclonal
|
Rat
(antiserum, ascites, unpurified) |
ELISA, IF, IH, IP, WB |
Human, Mouse, Rat |
immunogen = GST-human PS1 fusion protein (aa 21-80) |
Presenilin-1 |
- |
|
|
Acris Antibodies |
polyclonal
|
Rabbit
(unpurified antiserum) |
ELISA, IF, IH, IP, WB |
Human, Mouse, Rat, Xenopus |
immunogen = a 15 mer peptide (PS11-P) locating to the large hydrophilic loop of human or mouse Presenilin-1 |
Presenilin-1 |
- |
|
|
Acris Antibodies |
polyclonal
IgG |
Rabbit
(affinity purified with PBS, BSA and merthiolate) |
ELISA, IF, IH, IP, WB |
Human, Mouse, Rat, Xenopus |
immunogen = a 15 mer peptide (PS11-P) locating to the large hydrophilic loop of human or mouse Presenilin-1 |
Presenilin-1 |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, PBS, azide, affinity purified) |
WB |
Human, Mouse |
immunogen = synthetic peptide derived from within residues 1-100 of human PEN2, conj. to KLH |
PEN2 (12kDa); higher mwt bands also detected at ~50 and 100kDa due to portion of Pen2 bound to components of gamma secretase complex |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, whole serum) |
IP, WB |
Human |
immunogen = synthetic peptide (F Q I Y R P R W G A L G D Y L S F T I P L G T P) of human PEN2 |
Pen-2 protein |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, affinity purified, PBS, BSA, azide) |
WB |
Hamster, Mouse |
immunogen = synthetic peptide, A E S A E S G G P P G A Q D S A A, corr. to aa 2-18 of mouse ubiquilin |
~63 kDa ubiquilin |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, PBS, glycerol, BSA, azide, affinity purified) |
IF, WB |
Human |
immunogen = synthetic peptide from loop region of human Aph-1b; Epitope seq. C K L L K K A S E G L K S I N P G E T A P S M R |
Aph 1b |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, PBS, BSA, glycerol, azide, affinity purified) |
IF, WB |
Human |
immunogen = synthetic peptide containing the C- terminal seq. of human Aph 1b; Epitope seq. C Q D K N F L L Y N Q R S R Q D K N F L L Y N Q R S R |
Aph-1b |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, PBS, BSA, azide, affinity purified) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide derived from residues 50-150 of human APH1a |
recognises both isoforms of APH1a (encoded on chromosome 1) |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, PBS, glycerol, PBS, azide, affinity purified) |
IF, IP, WB |
Human, Mouse |
immunogen = synthetic peptide (C R R Q E D S R V M V Y S A L R I P P E D corresp. to C-terminal domain of the long isoform of aa 245-265 of human APH1a, conj. to KLH |
Anterior Pharynx Defective 1 (APH1a) |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, affinity purified, PBS, BSA, azide) |
WB |
Human, Mouse |
immunogen = synthetic peptide (I N A K A D V L F I A P R E P G A V S Y corr. to C-terminal aa 688-708 from human nicastrin |
~110 kDa nicastrin |
- |
|
|
ABGENT |
polyclonal
|
Rabbit
(liquid, PBS, azide, protein G purified) |
ELISA |
Human |
immunogen = synthetic peptide, 10-30 aa, at the N-term of first 110 aa of human APH1, conj. to KLH |
Aph1 |
- |
|
|
ABGENT |
polyclonal
|
Rabbit
(liquid, PBS, azide, protein G purified) |
ELISA |
Human |
immunogen synthetic peptide, 10-30 aa, at the C-term of last 50 aa of human APH1 |
Aph1 |
- |
|
|
ABGENT |
polyclonal
|
Rabbit
(liquid, PBS, azide, protien G purified) |
ELISA |
Human |
immunogen = synthetic peptide, 10-30 aa, at the N-term of first 50 aa of human PEN2, conj. to KLH |
Pen2 |
- |
|
|
ABGENT |
polyclonal
|
Rabbit
(liquid, PBS, azide, protein G purified) |
ELISA |
Human |
immunogen = synthetic peptide, 10-30 aa, at the N-term of first 60 aa of human PEN2 |
Pen2 |
- |
|
|
ABGENT |
polyclonal
|
Rabbit
(liquid, PBS, azide, protein G purified) |
ELISA |
Human |
immunogen = synthetic peptide (10-30 aa) at the N-term of first 100 aa of human PEN2, conj. to KLH |
Pen2 |
- |
|
|
ABGENT |
polyclonal
|
Rabbit
(liquid, PBS, azide) |
ELISA |
Human |
immunogen = synthetic peptide selected from the N-terminal region of human PEN2, conj. to KLH |
Pen2 |
- |
|
|
ABGENT |
polyclonal
|
Rabbit
(liquid, Ig fraction, PBS, azide) |
ELISA |
Human |
immunogen = synthetic peptide selected from the center region of human PEN2, conj. to KLH |
Pen2 |
- |
|
|
ABGENT |
polyclonal
|
Rabbit
(liquid, PBS, azide, protein G purified) |
ELISA, WB |
Human, Mouse |
immunogen = synthetic peptide (10-30 aa in length) at the N-term of first 100 aa of human Ubiquilin1, conj. to KLH |
ubiquilin1 |
- |
|
|
ABGENT |
polyclonal
|
Rabbit
(liquid, PBS, azide, protein G purified) |
ELISA, IH, WB |
Human, Mouse |
immunogen = synthetic peptide (10-30 aa in length) in the region of 336~351 of human Ubiquilin, conj. to KLH |
ubiquilin1 |
- |