The Antibodies database was archived in December 2022 and is no longer being updated. The Antibodies database is being supplanted by the AlzAntibodies database, which aims to provide detailed descriptions of selected antibodies.

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Antibodies

39 Results

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Compare Selected Antibodies

	Name	Source	Clonality & Isotype	Host & Formulation	Method	Reactivity	Immunogen/ Epitope	Specificity	Availability
Gap Junctions From labs (1)
	NCP1 /Caspr	antibodies developed by MA Bhat, Reference: Ziskin et al,, 2007	polyclonal	Guinea Pig	-	-	immunogen = sequences corresp. to the cytoplasmic region of NCP1	NCP1	-
Gap Junctions From manufacturers (38)
	ZO-1, mid region	Zymed/ Invitrogen	polyclonal Ig	Rabbit (antiserum, PBS, azide, affinity purified)	-	Dog, Human, Mouse, Rat	immunogen = synthetic peptide derived from the mid region of human ZO-1, which differs from dog, mouse, and rat by one conservative amino acid replacement	reacts with the ~225 kDa ZO-1 protein; bands of unknown origin may be observed at lower molecular weights.	-
	ZO-1 (ZO1-1A12)	Zymed/ Invitrogen	monoclonal IgG1,κ	Mouse (ascites, PBS, azide, protein-A purifiedAlso available FITC conj; 33-9111)	-	Dog, Human	immunogen = human recomb. ZO-1 fusion protein encompassing amino acids 334-634	reacts with the ZO-1α+ and ZO-1α- isoforms; is specific for ZO-1 proteins; cross-reactivity with the related ZO-2 protein has not been observed	-
	Occludin (OC-3F10)	Zymed/ Invitrogen	monoclonal IgG1,κ	Mouse (ascites, PBS, azide, protein-A purifiedAlso available FITC conj, 33-1511 andHRP conj, 33-1520)	-	Dog, Human, Mouse, Rat	immunogen = GST fusion protein consisting of the C-terminal (150 a.a.) of human occludin fused to GST	reacts specifically with mammalian occludin	-
	Occludin, N-term	Zymed/ Invitrogen	polyclonal Ig	Rabbit (antiserum, PBS, azide, affinity purified)	-	Human	immunogen = synthetic peptide derived from the N-terminal region of the human, rat, mouse, dog, and orangutan occludin proteins	reacts specifically with occludin	-
	Occludin, C-term	Zymed/ Invitrogen	polyclonal Ig	Rabbit (antiserum, PBS, azide, affinity purified)	-	Dog, Human, Mouse, Rat	immunogen = synthetic peptide derived from the C-terminal region of the human occludin protein	reacts with occludin, ~65 kDa	-
	Occludin, C-term GST	Zymed/ Invitrogen	polyclonal Ig	Rabbit (antiserum, PBS, azide, affinity purified)	-	Dog, Human	immunogen = GST-fusion protein containing the C-terminal region of human occludin protein	reacts with occludin, ~65 kDa	-
	Occludin	Zymed/ Invitrogen	polyclonal Ig	Rabbit (antiserum, PBS, azide, affinity purified using a GST-Occludin coupled gel)	-	Dog, Human, Mouse, Rat	immunogen = GST fusion protein consisting of the C-terminal 150 aa of human occludin fused to GST	reacts specifically with mammalian occludin	-
	ZO-1	Zymed/ Invitrogen	polyclonal Ig	Rabbit (antiserum, PBS, azide, affinity purified)	-	Dog, Human, Guinea Pig, Mouse, Rat	immunogen = 69 kD fusion protein corresp. to aa 463-1109 of human ZO-1 cDNA; the sequence lies N-terminal to the 80 aa region (the α-motif) present in the a+ isoform but absent in the a- isoform due to alternative splicing	reacts with the ZO-1α+ and ZO-1α- isoforms. Reactivity with dlg has not been characterized	-
	ZO-1, N-term	Zymed/ Invitrogen	polyclonal Ig	Rabbit (antiserua, PBS, BSA, azide, purified)	-	Human	immunogen = peptide sequence from the N-terminal region of human ZO-1	staining of ZO-1, in membrane, and may display cytoplasmic staining in tumor cells	-
	ZO-1, N-term	Zymed/ Invitrogen	polyclonal Ig	Rabbit (antiserum, PBS, azide, affinity purified)	-	Dog, Human, Mouse, Rat	immunogen = synthetic peptide derived from the N-terminal region of human, dog, mouse, and rat ZO-1	reacts with the ~225 kDa ZO-1 protein; bands of unknown origin may be observed at lower molecular weights.	-
	NCP1 /Caspr	Abcam	polyclonal IgG	Rabbit (liquid, PBS, BSA, azide, affinity purified)	-	Human, Mouse, Rat	immunogen = synthetic peptide derived from within residues 1350 to the C-terminus of mouse Caspr, conjugated to KLH	Caspr/NCP1	-
	NCP1 /Caspr (N-16)	Santa Cruz	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human, Mouse, Rat	immunogen = epitope mapping near the N-terminus of human Caspr	Caspr/NCP1	-
	NCP1 /Caspr (P-16)	Santa Cruz	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human, Mouse, Rat	immunogen = epitope mapping near the C-terminus of human Caspr	Caspr/NCP1	-
	NCP1 /Caspr (N-15)	Santa Cruz	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human, Mouse, Rat	immunogen = epitope mapping near the N-terminus of human Caspr	Caspr/NCP1	-
	Caspr2 (G-17)	Santa Cruz	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human, Mouse, Rat	immunogen = epitope mapping within an internal region of human Caspr2	Caspr2	-
	NCP1 /Caspr (H-66)	Santa Cruz	polyclonal IgG	Rabbit (liquid, PBS, azide, gelatin)	-	Human, Mouse, Rat	immunogen = epitope corresp. to aa1251-1316 mapping near the C-terminus of human Caspr	Caspr/NCP1	-
	Caspr2 (N-16)	Santa Cruz	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human	immunogen = epitope mapping near the N-terminus of human Caspr2	Caspr2	-
	Caspr2 (A-16)	Santa Cruz	polyclonal IgG	Goat (liquid, PBS, azide, gelatin, affinity purified)	-	Human, Mouse, Rat	immunogen = epitope mapping near the C-terminus of human Caspr2	Caspr2	-
	Occludin	Novus Biologicals	polyclonal	Mouse (mouse antisera, glycerol, no preservative)	-	Human	immunogen = OCLN (1 a.a. ~ 522 a.a) human protein	reacts with occludin	-
	ZO-1	Novus Biologicals	monoclonal IgG	Rat (ascites, azide)	-	Dog, Porcine, Mouse, Rat	immunogen = DOC-JR-plasma membranes from mouse liver	reacts with ZO-1 (membrane associated, non-integralmembrane protein)	-
	Connexin-26 (CX-12H10)	Invitrogen Corporation	monoclonal IgG1,κ	Mouse (affinity purified, liquid, PBS, azide)	-	Human, Mouse, Rat	immunogen = Synthetic peptide corresponding to a segment of the cytoplasmic loop of rat Connexin-26	monoclonal reacts strongly with Connexin-26, which has a predicted molecular weight of 26.5 kDa; anti-Cx26 appears to exhibit minimal cross reaction with Cx30 by western blotting	-
	Connexin-26 (CX-1E8)	Invitrogen Corporation	monoclonal IgG2a,κ	Mouse (protein-A purified, liquid, PBS, azide)	-	Human, Mouse, Rat	immunogen = a 13 amino acid synthetic peptide derived from the C-terminus of the mouse Connexin 26 protein. This mouse sequence differs from the rat sequence by a single amino acid and from the human sequence by two (non-consecutive) amino acids	monoclonal reacts with the Connexin 26 protein; no cross-reactivity with the closely related Connexin 30 protein has been observed.	-
	Connexin-43 (3D8A5)	Invitrogen Corporation	monoclonal IgG1	Mouse (protein-A purified, liquid, PBS, azide)	-	Mouse, Rat	immunogen = synthetic peptide derived from rat Connexin 43	monoclonal reacts specifically with both phosphorylated and non-phosphorylated forms of Connexin 43; does not react with the Connexin 43 dimer, but reacts with non phosphorylated forms migrating at ~41 kD and phosphorylated forms migrating between 43 kD and 45 kD	-
	Connexin-26 (UM214)	Invitrogen Corporation	polyclonal	Rabbit (antiserum, affinity purified, PBS, azide)	-	Mouse, Rat	immunogen = a 13 amino acid synthetic peptide derived from the C-terminus of the mouse Connexin 26 protein. This mouse sequence differs from the rat sequence by a single amino acid and from the human sequence by two (non-consecutive) amino acids	polyclonal detects the Connexin 26 protein; no cross-reactivity with the closely related Connexin 30 protein has been observed	-
	Connexin-26 (Z-Z8)	Invitrogen Corporation	polyclonal	Rabbit (affinity purified, liquid, PBS, azide)	-	Mouse, Rat	immunogen = peptide corresponding to a portion of the cytoplasmic loop of rat Connexin-26	polyclonal detects predominantly Connexin 26, 26 kDa; a few cross reactive bands were detected in the 45-50 kDa range	-
	Connexin-43 phos S368 (ZMD640)	Invitrogen Corporation	polyclonal	Rabbit (affinity purified, liquid, HEPES, saline, BSA, glycerol)	-	Rat	immunogen = phosphopeptide corresp. to amino acid residues surrounding the phosphoserine 368 of rat connexin 43	polyclonal specific for the ~43 kDa connexin 43 protein phosphorylated at serine 368	-
	Connexin-43 (CX-1B1)	Invitrogen Corporation	monoclonal IgG1,κ	Mouse (affinity purified, liquid, PBS, azide)	-	Dog, Human, Mouse, Rat	immunogen = synthetic peptide corresp. to a cytoplasmic sequence located near the C-terminus of rat Connexin 43	monoclonal CX-1B1 recognizes Connexin 43 only when the serine at residue 368 is unphosphorylated, but will recognize Connexin 43 if it is phosphorylated at sites besides Ser368	-
	Connexin-43 (CX-1B1)	Invitrogen Corporation	monoclonal IgG1,κ	Mouse (ascites, protein-A purified, liquid, PBS, BSA, azide, Alexa Fluor 488 conj.)	-	Dog, Human, Mouse, Rat	immunogen = synthetic peptide corresponding to a cytoplasmic sequence located near the C-terminus of rat Connexin 43	monoclonal CX-1B1 is specific for one of the unphosphorylated forms of Connexin 43; CX-1B1 recognizes Connexin 43 only when the serine at residue 368 is unphosphorylated. CX-1B1 will, however, recognize Connexin 43 if it is phosphorylated at sites besides Ser368.	-
	Connexin-26 (O-24)	Santa Cruz	polyclonal	Rabbit (purified, liquid, PBS, azide, gelatin)	-	Human, Mouse	immunogen = apeptide mapping near the C-terminus of connexin 26 of human origin	polyclonal detects Connexin 26, 26 kDa	-
	Connexin-26 (N-19)	Santa Cruz	polyclonal	Goat (affinity purified, liquid, PBS, azide, gelatinAlso available as rabbit rabbit, sc-7261-R)	-	Human, Mouse, Rat	immunogen = a peptide mapping at the N-terminus of connexin 26 of human origin	polyclonal for detection of connexin 26, and toa lesser extent, connexin 30	-
	Connexin-43 (D-7)	Santa Cruz	monoclonal IgG1	Mouse (liquid, PBS, azide, gelatin)	-	Dog, Human, Mouse, Rat	immunogen = aminoacids 241-254 within the cytoplasmic domain of connexin 43 of rat origin	monoclonal CXN-6 is recommended for detection of connexin 43.	-
	Connexin-43 (CXN-6)	Santa Cruz	monoclonal IgM	Mouse (ascites, azide)	-	Cow, Human, Mouse, Rat	immunogen = aminoacids 362-381 of connexin 43 of human origin	monoclonal CXN-6 is recommended for detection of connexin 43.	-
	Connexin-43 (C-20)	Santa Cruz	polyclonal IgG	Goat (liquid, affinity purified IgG, PBS, azide, gelatin.Also available sc-6560 AC, agarose conj.)	-	Dog, Zebra fish, Cow, Human, Mouse, Rat, Xenopus	immunogen = a peptide mapping at the C-terminus of connexin 43 of human origin	recommended for detection of connexin 43.	-
	Connexin-43 (H-150)	Santa Cruz	polyclonal IgG	Rabbit (liquid IgG, PBS, azide, gelatin)	-	Zebra fish, Human, Mouse, Rat, Xenopus	immunogen = aminoacids 233-382 mapping at the C-terminus of connexin 43 of human origin	recommended for detection of connexin 43.	-
	Connexin-43	Invitrogen Corporation	polyclonal	Rabbit (affinity purified, liquid, PBS, azide)	-	Human, Mouse, Rat	immunogen = peptide corresponding to a segment of the 3rd cytoplasmic domain (C-terminal portion) of rat connexin 43	polyclonal detects Connexin 43, 43 kDa; reactivity of this antibody with connexin 43 is independent of phosphorylation status	-
	Connexin-43	Chemicon and Upstate are Millipore	polyclonal	Rabbit (affinity purified, liquid, Tris, BSA, azide)	-	Bovine, Mouse, Rat	immunogen = a 19 amino acid C-terminal peptide sequence within the cytoplasmic domain of mouse Cx43, coupled to KLH	immunogenic peptide sequence is specific for Cx43 and no significant homology is seen with other connexins. The mouse Cx43 peptide sequence shows 100% conserved with rat and bovine, and 84% with chicken and human (16/19 aa).	-
	Connexin-43	Chemicon and Upstate are Millipore	polyclonal	Rabbit (purified, liquid, phosphate buffer, saline, azide)	-	Human, Mouse, Rat	immunogen = a 23 amino acid C-terminal peptide sequence within the cytoplasmic domain of mouse Cx43	immunogenic peptide sequence is specific for Cx43 and no significant homology is seen with other connexins. The mouse Cx43 peptide sequence is 100% homologous with rat and human Cx43	-
	Connexin-26	Chemicon and Upstate are Millipore	polyclonal	Rabbit (affinity purified, liquid, Tris, BSA, azide)	-	Mouse	immunogen = a 19 amino acidpeptide sequence located near the C-terminal, second cytoplasmic domain of mouse Cx26; conjugated to KLH as a carrier protein	specific for Connexin-26	-