|
|
Accurate |
polyclonal
|
Goat
|
- |
- |
44-63aa of N-Terminus |
- |
- |
|
|
Accurate |
monoclonal
|
(Supernat.) |
IH |
Human |
- |
|
- |
|
|
Accurate |
monoclonal
|
|
- |
- |
- |
- |
- |
|
|
Accurate |
polyclonal
|
Goat
(serum) |
WB, ELISA |
- |
|
|
- |
|
|
Accurate |
polyclonal
|
Goat
(serum) |
IH, WB |
Human |
- |
frameshift mutant |
- |
|
|
Accurate |
polyclonal
|
Rabbit
|
- |
Human |
|
APP, C-terminal |
- |
|
|
Accurate |
polyclonal
|
Rabbit
|
- |
Human |
|
APP, N-terminal |
- |
|
|
Innovex Biosciences |
monoclonal
|
Mouse
|
- |
- |
|
|
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, PBS, BSA, azide, affinity purified, prediluted) |
IC, IF, IH |
Human, Mouse, Rat |
immunogen = synthetic peptide to N-terminal of human APP |
recognizes APP (β-APP770) and is predicted to recognize β-APP695 and β-APP751; IHC stains both cytoplasmic and extracellular areas. |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, PBS, azide, protein A purified) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide, corresp. to aa 653-662 of human APP (and 1-10 of the β-amyloid peptide). |
recognises both intact APP and the 4kD β-amyloid peptide that is generated by the action of β- and γ-secretases |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, PBS, protein A purified) |
IC, IH, IP, WB |
Human, Mouse, Rat |
immunogen = synthetic peptide corresp. to residues surrounding Thr668 of human APP695, conjugated to KLH |
detects different isoforms of amyloid β- (A4) precursor protein only when phosphorylated at Thr668 (position corresponds to APP695 isoform). |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, HEPES, NaCl, BSA, no preservative, protein A purified) |
IC, IH, IP, WB |
Human, Mouse, Rat |
immunogen = synthetic peptide corresp. to residues surrounding Thr668 of human APP695, conjugated to KLH |
detects different isoforms of endogenous amyloid β- (A4) precursor protein only when phosphorylated at Thr668 (position corresponds to APP695 isoform). |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, whole serum, PBS, azide) |
IC, IH, IP, WB |
Human, Monkey |
immunogen = synthetic peptide to C-terminal of human APP |
APP; may react with APLP1 and APLP2. |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, whole serum, azide) |
ELISA, WB |
Human |
immunogen = synthetic peptide corresp. to C-terminal aa 681-695 of human APP, conj. to KLH |
APP (100kDa); may react with APLP2 |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, whole serum, azide) |
ELISA, WB |
Human |
immunogen = synthetic peptide (unfortunately, the aa sequence is considered to be commercially sensitive) from human APP KPI Domain. |
recognizes soluble APP and synthetic peptide corresponding to a part of KPI Domain in soluble APP by ELISA. |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, whole serum, azide) |
IC, IP, WB |
Human, Monkey, Rat |
immunogen = synthetic peptide from C-terminal human APP conj. to KLH |
reacts with membrane-associated APP695, APP751 and APP770, as well as C-terminal membrane stubs |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, whole serum, azide) |
IC, IP, WB |
Human, Monkey, Rat |
immunogen = synthetic peptide from C-terminal human APP conj. to KLH |
reacts with APP695, APP751 and APP770 |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, whole serum, azide) |
IC, IP, WB |
Human, Macaque |
immunogen = synthetic peptide from C-terminal corresp. to the OX-2 domain of human APP770, conj. to KLH |
recognises the OX2 domain which is only present in APP770 in cells that express the recombinant APP770 (low endogenous levels) |
- |
|
|
Axxora |
polyclonal
IgG |
Rabbit
(liquid, purified IgG, PBS, azide) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide corresp. to aa 653 -662 of human APP A4, or aa 1-10 of the 4k Aβ peptide generated by β- and γ-secretases |
APP (~102kDa) |
- |
|
|
Axxora |
polyclonal
IgG |
Rabbit
(antiserum, purified, PBS, azide) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide corresp. to C-terminal aa 737-751 of APP A4, or aa 85-99 of the C99 fragment generated by β-secretase |
APP (~102kDa WB) |
- |
|
|
Biosource Invitrogen |
polyclonal
|
Rabbit
(liquid, serum, affinity purified, PBS, BSA, azide) |
ELISA, WB |
Human |
immunogen = synthetic peptide from the C-terminus of human APP |
immature APP (95 kDa) also APP holoprotein, a post translationally modified protein (100-120 kDa) |
- |
|
|
Histo-Line |
polyclonal
|
Rabbit
(liquid, Ig frac., PBS, azide, purified) |
IH |
Human, Mouse, Rat |
immunogen = synthetic peptide corresp. to N-terminal of human APP |
APP, APLP and β-APP770 |
- |
|
|
Histo-Line |
polyclonal
|
Rabbit
(liquid, PBS, azide, affinity purified) |
IH, IP, WB |
Human, Mouse |
immunogen = synthetic peptide derived from C-terminus of human and mouse AβPP(APP695) |
full length APP; APLP; C99 C-terminal cleavage frag. |
- |
|
|
Histo-Line |
monoclonal
IgG1κ |
Mouse
(liquid, ascites, Ig frac., PBS, azide) |
ELISA, IH, IP, WB |
Human |
immunogen = rh β-APP695; epitope within the first 200 aa in the β-APP N-terminus |
β-APP 695, 751, 770 |
- |
|
|
Histo-Line |
polyclonal
|
Rabbit
(liquid, PBS, azide, affinity purified) |
IF, IH, WB |
Pig, Human, Mouse, Rat |
immunogen = 22 aa synthetic peptide from the C-terminal of human β-APP |
β-APP full length (APP695, 751, 770); N-terminal truncated forms of β-APP; C-terminal membrane-anchored frag. of β-APP after α- or β-secretase cleavage. Not β-APP product N-terminal to the γ-secretase cleavage site |
- |
|
|
MoBiTec GmbH |
polyclonal
IgG |
Rabbit
(PBS, purified, azide, pos. control, blocking peptide) |
WB |
Human, Mouse, Rat |
synthetic peptide, aa. 737-751 of APP A4, or 85-99 of the C99 fragment generated by β-secretase |
APP and the C99 fragment |
- |
|
|
BD Pharmingen |
monoclonal
IgG2a |
Mouse
(liquid, PBS, BSA, glycerol, azide, purified) |
WB |
Dog, Human, Mouse, Rat |
immunogen = peptide corr. to aa 348-464 of human APP-BP1 |
APP binding protein 1 |
- |
|
|
BD Pharmingen |
polyclonal
|
Rabbit
(liquid, purified, PBS, azide) |
WB |
Mammal (various), Chicken, Human, Mouse, Rat |
peptide corr. to aa 653-652 of human APP or 1-10 of the 4 kDa Aβ peptide. Peptide sequence identical in rabbit, pig, bovine, guinea pig and chicken |
APP |
- |
|
|
BD Pharmingen |
polyclonal
|
Rabbit
(aqueous buffered liquid, azide) |
WB |
Mammal (various), Chicken, Human, Mouse, Rat |
peptide corr. to aa 737-751 of human APP or 85-99 of the C99 fragment generated by β-secretase cleavage. Peptide sequence identical in monkey, mouse, rat and chicken |
APP |
- |
|
|
ProSci |
polyclonal
IgG |
Rabbit
(PBS, purified, azide, pos. control [#1403], blocking peptide [#2133P]) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide, aa. 653-662 of APP A4, or 1 to 10 of the 4K Aβ peptide generated by β- and γ-secretases |
APP and Aβ peptide |
- |
|
|
ProSci |
polyclonal
IgG |
Rabbit
(PBS, purified, azide, pos. control [#1403], blocking peptide [#2136P]) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide, aa. 737-751 of APP A4, or 85-99 of the C99 fragment generated by β-secretase |
APP and the C99 fragment |
- |
|
|
Phospho- solutions |
polyclonal
IgG |
Rabbit
(liquid, HEPES, NaCl, BSA, glycerol, affinity purified) |
WB |
Dog, Primate (various), Human, Mouse, Rat |
immunogen = peptide corresp. to aa residues from the C-terminal region of rat APP |
APP (~115k) |
- |
|
|
R&D Systems |
polyclonal
|
Rabbit
(affinity purified, PBS, lyophilized) |
WB |
Human |
immunogen = synthetic peptide (C M R M G R G R T S S K E LA) of human APP+1 Frameshift Mutant |
APP+1 |
- |
|
|
R&D Systems |
polyclonal
IgG |
Goat
(lyophilized, PBS, trehalose, affinity purified) |
IP, WB |
Human |
immunogen = purified, NSO-derived, recombinant human APLP (aa 34 -580) |
APLP-1 |
- |
|
|
R&D Systems |
polyclonal
IgG |
Rabbit
(lyophilized, PBS, trehalose, affinity and protein A purified) |
WB |
Human, Mouse |
immunogen = synthetic phospho-peptide corresp. to residues surrounding T668 of human APP695 |
detects multiple isoforms of endogenous phospho-APP695 (T668) |
- |
|
|
R&D Systems |
polyclonal
IgG |
Goat
(lyophilized, PBS, trehalose, affinity purified) |
ELISA, IP, WB |
Mouse |
immunogen = purified, NSO-derived, recombinant mouse APLP (aa 37 -582) extracellular domain |
APLP-1 extracellular domain |
- |
|
|
R&D Systems |
polyclonal
IgG |
Goat
(affinity purified, PBS, lyophilized) |
ELISA, IH, WB |
Human |
immunogen = purified, insect cell line Sf21-derived, recombinant human +1 frameshift mutant of APP695 |
rhAPP695+1 and rhAPP770 (common epitope) |
- |
|
|
R&D Systems |
polyclonal
IgG |
Goat
(affinity purified, PBS, lyophilized) |
ELISA, WB |
Human |
immunogen = purified, insect cell line Sf21-derived, recombinant human +1 frameshift mutant of APP695 |
rhAPP695+1 |
- |
|
|
R&D Systems |
monoclonal
IgG1 |
Mouse
(supernate, protein-G, PBS, lyophilized) |
IP, WB |
Human |
immunogen = purified, insect cell line Sf21-derived, recombinant human +1 frameshift mutant of APP695 |
rhAPP695+1 and rhAPP770 (common epitope) |
- |
|
|
R&D Systems |
monoclonal
IgG |
Mouse
(lyophilized, PBS, trehalose, affinity and protein G purified) |
IH, WB |
Human, Mouse |
immunogen = synthetic phospho-peptide corresp. to residues surrounding T668 of human APP695 |
detects multiple isoforms of endogenous phospho-APP695 (T668) |
- |
|
|
R&D Systems |
polyclonal
IgG |
Goat
(lyophilized, PBS, BSA, affinity purified, biotinylated) |
WB |
Mouse |
immunogen = purified, NSO-derived, recombinant mouse APLP (aa 37 -582) extracellular domain |
APLP-1 extracellular domain |
- |
|
|
RDI /Fitzgerald |
monoclonal
IgG1 |
Mouse
(purified, lyophilized) |
WB |
Human, Rat |
synthetic peptide of aa. 511-608 from APP A4(695) |
WB reacts to natural APP A4(695), IH stains plaques |
- |
|
|
RDI /Fitzgerald |
monoclonal
IgG1 |
Mouse
(Potassium PBS, BSA, purified lyophilized) |
IH, WB |
Fish (various), Human, Monkey, Mouse, Rat |
immunogen = purified recombinant N-terminal on the pre-A4 fusion protein |
pre-A4, N-terminal |
- |
|
|
RDI /Fitzgerald |
monoclonal
IgM |
Mouse
(supernatant, azide, lyophilized) |
IH, WB |
Human |
immunogen = prokaryotic recombinant fusion protein corresp. to the extracellular portion of APP between the KPI and β-amyloid region |
APP; stains neurofibrillary tangles and senile plaques |
- |
|
|
RDI /Fitzgerald |
monoclonal
IgG1 |
Mouse
|
IH, WB |
Fish (various), Human, Monkey, Mouse, Rat |
- |
large pyramidial cells, neurons, astrocytes and microglia |
- |
|
|
AbD Serotec |
polyclonal
IgG |
Rabbit
(liquid, purified, PBS, azide) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide, aa 653-662 of human APP or aa 1-10 of the β-amyloid peptide |
intact APP and the 4kD β-amyloid generated by β-, γ-secretases |
- |
|
|
AbD Serotec |
polyclonal
|
Goat
(liquid, serum, azide) |
ELISA, WB |
Human |
immunogen = purified synthetic peptide, aa 681-695 at C-terminus of human APP |
APP |
- |
|
|
AbD Serotec |
polyclonal
|
Goat
(liquid, serum, azide) |
IH, WB |
Human |
immunogen = purified synthetic peptide, aa 339-348 at C-terminus of APP frameshift mutant (APPFM) |
binds to truncated APPFM; labels dystrophic neurites in senile plaques |
- |
|
|
AbD Serotec |
polyclonal
IgG |
Rabbit
(liquid, purified, PBS, azide) |
IH, IP, WB |
Human, Monkey |
immunogen = synthetic peptide composed of aa 292-312 from the KPI domain of human APP |
recognises an epitope in the Kunitz protease inhibitor (KPI) domain of APP |
- |
|
|
AbD Serotec |
polyclonal
IgG |
Rabbit
(liquid, serum, azide) |
IP, WB |
Human, Monkey |
immunogen = highly purified antigen |
recognises an epitope within the OX-2 domain of APP |
- |
|
|
AbD Serotec |
polyclonal
IgG |
Rabbit
(liquid, serum, azide) |
IP, WB |
Human, Monkey, Mouse |
immunogen = highly purified antigen |
recognises all forms of APP |
- |
|
|
AbD Serotec |
polyclonal
IgG |
Rabbit
(liquid, purified, PBS, azide) |
IH, WB |
Human, Mouse, Rat |
immunogen = synthetic peptide, aa 737-751 of human APP |
intact APP and the C99 (aa 85-99) fragment generated by β-secretase |
- |
|
|
AbD Serotec |
polyclonal
|
Rabbit
(liquid, serum, azide) |
IH, IP, WB |
Human, Monkey |
immunogen = purified synthetic peptide from C-terminus of APP |
recognises an epitope at the C-terminus of APP |
- |
|
|
Sigma Aldrich |
kit
|
Unknown Host
|
ELISA |
Human |
- |
detect and quantify isoforms of APP770, 751, 733 and 695 |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, Hepes, BSA, NaCl, glycerol, protein A purified) |
ELISA, IH, WB |
Human, Monkey, Mouse |
immunogen = synthetic peptide corresp. to residues surrounding T668 of human APP, conj. to KLH |
detects total levels of several isoforms of both mature and immature amyloid beta (A4) precursor protein, including APP695, APP770 and APP751 |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, PBS, BSA, azide, affinity purified) |
IP, WB |
Mouse |
immunogen = synthetic peptide derived from within residues 750 to the C-terminus of human APP phosphory. at Y757, conjugated to KLH |
various isoforms of APP in the phosphorylated state i.e. mature (~80 kDa), immature (~110 kDa), C-terminal (~50 kDa) |
- |
|
|
Abcam |
monoclonal
IgG1 |
Mouse
(liquid, protein-G, BSA, TBS, azide, Biotin conj.) |
WB |
Cow, Pig, Human, Monkey |
immunogen = synthetic peptide corresp. to residues 1-17 of Human Amyloid Precursor Protein |
recognizes Amyloid Precursor Protein (APP) |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, affinity purified, PBS, azide) |
WB |
Human, Mouse, Rat |
immunogen = sequence (D A E F R H D S G Y) corr. to aa 653 to 662 of human amyloid A4 protein precursor. Identical to that of rabbit, pig, bovine, guinea pig and chicken |
detects APP and Ab peptide |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, affinity purified, PBS, azide) |
IH, WB |
Human, Mouse |
immunogen = seq. corresp. to G Y E N P T Y K F F E Q M Q N) aa 737-751of human amyloid A4 protein precursor (APP) or aa 85-99 of the 4K Aβ peptide generated by β- and γ-secretases |
detects APP and Aβ peptide |
- |
|
|
Abcam |
polyclonal
IgG |
Goat
(liquid, whole antiserum, no preservative) |
ELISA, WB |
Human |
immunogen = synthetic peptide conjugated to BSA, corr. to aa 681-695 of human APP |
detects ~92.4 kDa APP, C-terminal |
- |
|
|
Abcam |
polyclonal
IgG |
Goat
(liquid, whole antiserum, no preservative) |
ELISA, IH, WB |
Human, Mouse |
immunogen = synthetic peptide (H M N V W N G K W D S D P S G T K T C I) corr. to N-terminal aa 44-63 of human APP |
detects ~92.4 kDa APP; IHC: labels dystrophic neurites in senile plaques;WB for cell lysates and N-fragment secreted |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, PBS, BSA, azide, affinity purified) |
IC, IF, IH, WB |
Human, Mouse, Rat |
immunogen = synthetic peptide (H M N V Q N G K W D S D P S G T K T C) corresp. to N-terminal aa 44-62 of human APP |
recognizes APP (β-APP770) and is predicted to recognize β-APP695 and β-APP751; IHC stains both cytoplasmic and extracellular areas. |
- |
|
|
Abcam |
polyclonal
IgG |
Goat
(liquid, whole serum, thimerosal) |
ELISA, IH, WB |
Human |
immunogen = synthetic peptide (A V C G S A M S Q S L L) corresp. to aa 339-348 of human APP |
recognizes APP Frameshift Mutant (APPFM). |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, PBS, BSA, azide, affinity purified) |
IC, IF, IH, WB |
Human, Mouse, Rat |
immunogen = synthetic peptide (H M N V Q N G K W D S D P S G T K T C) corresp. to N-terminal aa 44-62 of human APP |
recognizes APP (β-APP770) and is predicted to recognize β-APP695 and β-APP751; IHC stains both cytoplasmic and extracellular areas. |
- |
|
|
Abcam |
polyclonal
IgG |
Goat
(liquid, whole antiserum, no preservative) |
ELISA, IH, WB |
Human |
immunogen = synthetic peptide corr. to aa 339-348 of the C-terminal human APP frameshift mutant |
labels dystrophic neurites in senile plaques and reacts with neurons containing the APPFM protein |
- |
|
|
Abcam |
polyclonal
IgG |
Goat
(liquid, whole antiserum, azide) |
ELISA, IH, WB |
Human |
immunogen = synthetic peptide (R G R T S S K E L A) corr. to aa 339-348 of human APP frameshift mutant |
cellular localization: cell membrane, cytoplasmic, ER and Golgi Apparatus |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, whole antiserum, azide) |
IP, WB |
Human, Monkey |
immunogen = OX-2 domain (Human) |
recognises an epitope within the OX-2 domain of human APP |
- |
|
|
Abcam |
monoclonal
IgG |
Rabbit
(liquid, tris-glycine saline, glycerol, azide) |
FC, IC, IH, IP, WB |
Human, Mouse, Rat |
immunogen = synthetic peptide corresp. to residues in the NPXY motif of human Amyloid β A4 precusor (APP). |
recognizes Amyloid beta precursor protein and its isoforms. It will not recognize either of the two Amyloid-β protein variants, Amyloid-β 1-40 or Amyloid-β 1-42. |
- |
|
|
Abcam |
polyclonal
IgG |
Rabbit
(liquid, whole serum, azide) |
IC, IH, IP, WB |
Human, Mouse, Macaque |
immunogen = synthetic peptide from within human KPI domain of human APP751/770, conj. to KLH |
recognises both APP751 and APP770 which contain the KPI domain |
- |
|
|
Sigma Aldrich |
polyclonal
IgG |
Rabbit
(IgG frac, PBS, azide) |
IH |
Human, Mouse, Rat |
immunogen = KPI domain (aa 301-315) of APP770 |
KPI domain, APP770 |
- |
|
|
AbD Serotec |
polyclonal
|
Goat
(liquid, purified, PBS, azide) |
ELISA, WB |
Human, Mouse, Rat |
immunogen = synthetic peptide, G Y E N P T Y K F F E Q M Q N, corresp. to the C-terminal aa seq. 681-695 of human APP (isoform APP695) conjugated to a protein carrier |
APP C-terminal |
- |
|
|
AbD Serotec |
polyclonal
|
Goat
(liquid, PBS, azide, protein G purified) |
ELISA, IH, WB |
Human |
immunogen = purified synthetic peptide, R G R T S S K E L A, aa 339-348 at C-terminus of APP frameshift mutant (APPFM) |
residues 339-348 on the mid-portion of APP frameshift mutant protein |
- |
|
|
AbD Serotec |
polyclonal
|
Goat
(liquid, PBS, azide) |
ELISA, IH |
Human |
immunogen = synthetic peptide |
APP residued 44-63 on N-terminus |
- |
|
|
Leinco Technologies |
polyclonal
|
Rabbit
(liquid, PBS, azide, affinity purified) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide corresp. to aa 653-662 of human APP or 1-10 of the 4K Aβ peptide generated by β- or γ-secretases |
β-APP |
- |
|
|
Leinco Technologies |
polyclonal
|
Rabbit
(liquid, PBS, azide, affinity purified) |
WB |
Human, Mouse, Rat |
immunogen = synthetic peptide corresp. to aa 737-751 of human APP or 85-89 of the C99 fragment generated by β-secretase cleavage |
β-APP |
- |
|
|
Santa Cruz |
polyclonal
IgG |
Goat
(liquid, affinity purified, PBS, gelatin, azide; blocking peptide [sc-23821P]) |
IF, WB |
Human, Mouse, Rat |
immunogen = peptide mapping within an extracellular domain of human APLP2 |
APLP2 |
- |
|
|
Santa Cruz |
polyclonal
IgG |
Goat
(affinity purified, IgG, PBS, gelatin, azide; blocking peptide [sc-23822P]) |
IF, WB |
Human, Mouse, Rat |
immunogen = peptide mapping within an extracellular domain of human APLP2 |
APLP2 |
- |
|
|
Santa Cruz |
polyclonal
IgG |
Goat
(liquid, affinity purified, PBS, gelatin, azide; blocking peptide [sc-26715P]) |
IF, WB |
Drosophila |
immunogen = peptide mapping within an C-terminus of APPL of Drosophila melanogaster origin |
APPL |
- |
|
|
Sigma Aldrich |
polyclonal
IgG |
Rabbit
(liquid, PBS, BSA, azide, affinity purified) |
IB, IH |
Frog, Human, Mouse, Rat |
immunogen = synthetic phos-phorylated peptide derived from the region of human APP that contains threonine 668 |
APP phosphorylated at threonine 668 |
- |
|
|
Santa Cruz |
polyclonal
IgG |
Goat
(liquid, affinity purified, PBS, gelatin, azide; blocking peptide [sc-26716P]) |
IF, WB |
Drosophila |
immunogen = peptide mapping within an C-terminus of APPL of Drosophila melanogaster origin |
APPL |
- |
|
|
R&D Systems |
kit
IgG |
Unknown Host
(capture antibody = monoclonal anti-human APP; detection antibody = biotinylated anti-human APP) |
ELISA |
Human |
- |
quantitate APP (natural and recombinant in supernates and serum) |
- |
|
|
R&D Systems |
polyclonal
IgG |
Rabbit
(liquid, HEPES, NaCl, BSA, glycerol, affinity purified) |
WB |
Dog, Primate (various), Human, Mouse, Rat |
immunogen = peptide corresp. to aa residues from the C-terminal region of rat APP |
specific for the ~120kDa APP |
- |
|
|
R&D Systems |
polyclonal
IgG |
Goat
(lyophilized, PBS, trehalose, affinity purified) |
ELISA, WB |
Mouse |
immunogen = purified, NSO-derived, recombinant mouse APLP-2 extracellular domain |
APLP-2 extracellular domain |
- |
|
|
Santa Cruz |
polyclonal
|
Goat
(affinity pruified, IgG, PBS, gelatin, azide; blocking peptide [sc-23818P]) |
IF, WB |
Human, Mouse, Rat |
immunogen = peptide mapping within an extracellular domain of APLP1 of human origin |
APLP1 |
- |
|
|
Novus Biologicals |
polyclonal
IgG |
Rabbit
(liquid, PBS, BSA, azide, affinity purified) |
IH, WB |
Human, Mouse, Rat |
immunogen = synthetic peptide corresp. to aa residues from the N-terminal region of human APP |
APP 770, 695 and 751 |
- |
|
|
Novus Biologicals |
polyclonal
IgG |
Rabbit
(liquid, PBS, BSA, azide, prediluted) |
IH |
Human, Mouse, Rat |
immunogen = synthetic peptide corresp. to aa residues from the N-terminal region of human APP |
APP |
- |
|
|
Novus Biologicals |
polyclonal
IgG |
Rabbit
(liquid, PBS, BSA, azide, affinity purified) |
WB |
Human, Mouse, Rat |
immunogen = peptide sequence corresp. to aa 653-662 of human amyloid A4 protein precursor (APP); epitope D A E F R H D S G Y |
APP |
- |
|
|
Novus Biologicals |
polyclonal
IgG |
Rabbit
(liquid, whole sera, azide) |
ELISA, WB |
Human |
immunogen = synthetic peptide (the aa sequence is considered to be commercially sensitive)(human) (KPI domain) |
recognizes soluble APP and synthetic peptide corresp. to a part of KPI Domain in soluble APP |
- |
|
|
Novus Biologicals |
monoclonal
IgG2b,κ |
Mouse
(liquid, PBS, purified, no preservative) |
ELISA |
Human |
immunogen = APLP2 (AAH00373, 41 a.a. ~ 150 a.a) partial recombinant protein with GST tag |
amyloid beta (A4) precursor-like protein 2 |
- |
|
|
LifeSpan Biosciences, Inc. |
monoclonal
|
Rabbit
(liquid, supernatant) |
FC, IC, IH, IP, WB |
Human |
immunogen = synthetic peptide corresp. to residues in the NPXY motif of human Amyloid Beta A4 precusor (APP) |
APP |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(DEAE-column chromatogaphy) |
ELISA, IF, IH, IP, WB |
Pig, Human, Mouse, Rat |
immunogen = 22 aa synthetic peptide derived from the C-terminus of the human beta-amyloid precursor protein (beta-APP) |
APP; reacts with full-length (APP695, 751, 770) and N-terminal truncated forms of beta-APP; also detect the C-terminal membrane-anchored fragment of beta-APP that remains after alpha- or beta-secretase cleavage; not the beta-APP product N-terminal to the gamma-secretase cleavage site |
- |
|
|
LifeSpan Biosciences, Inc. |
polyclonal
|
Rabbit
(affinity purified) |
ELISA, IF, IP, WB |
Human |
immunogen = beta amyloid peptide, D A E F R H D S G Y E V H H, conj. to KLH using maleimide ( aa 1-14 of human beta amyloid) |
APP |
- |