APP frameshift mutant
Biotrend
polyclonal
IgG
Goat
(liquid, Ig fract, PBS, purified, azide)
-
Human
immunogen = synthetic peptide (R G R T S S K E L A) corresp. to aa229-348 of the C-terminus of human APP frameshift mutant (APPFM)
residues 339-348 of APP, Frameshift mutant
-
APP (3E9)
Biotrend
monoclonal
IgG1
Mouse
(lyophilized, PBS, sucrose, protein A purified)
-
Human, Mouse
immunogen = 21 aa synthetic peptide (L E V P T D G N A G L L A E P Q I A M F C) based on the human APP695 (residues 18-38)
APP
-
APP
Biotrend
polyclonal
IgG1
Rabbit
(liquid, PBS, azide)
-
Human, Mouse, Rat
immunogen = human APP synthetic peptide corresp. to aa residues 737-751 of the full length protein or to residues 85-99 in the human C99 fragment generated by γ-secretase cleavage.
APP (~105kDa) and C99 fragment (35kDa)
-
APP
Biotrend
polyclonal
IgG1
Rabbit
(liquid, PBS, azide)
-
Human, Mouse, Rat
immunogen = human APP synthetic peptide corresp. to aa residues 737-751 of the full length protein or to residues 85-99 in the human C99 fragment generated by γ-secretase cleavage.
APP (~105kDa) and C99 fragment (35kDa)
-
APP
Biotrend
polyclonal
Rabbit
(liquid, Ig fract, purified)
-
Human, Mouse, Rat
immunogen = synthetic peptide corresp. to N-terminal of human APP
recognizes amyloid precursor protein (β-APP770), amyloid precursor protein (APP) and APP-like proteins
-
APP binding family B, 1
Biotrend
polyclonal
Goat
(liquid, Ig fract, TBS, azide, BSA, affinity purified)
-
Human, Mouse
immunogen = peptide seq. C-G S L K P K P L G A H T P, from the C-terminus of the protein seq.
recognizes both isoforms (NP_001155.1 and NP_663722.1
-
APP binding family A, 1
Biotrend
polyclonal
Goat
(liquid, Ig fract, TBS, azide, BSA, affinity purified)
-
Human, Mouse, Rat
immunogen = peptide seq. C-E A S H P S Q D G K R Q Y K, from the internal region of the protein seq. according to NP_001154.2
APBA1/MINT1
-
APLP1, C-term
Calbiochem EMD Biosciences
polyclonal
IgG
Rabbit
(undiluted serum, liquid, no preserve)
-
Human, Mouse, Rat
immunogen = synthetic peptide (N P T Y R F L E E R P) aa 643-653 at the C-terminus of APLP1, coupled to KLH
APLP1; not APP or APLP2
-
APLP2, C-term
Calbiochem EMD Biosciences
polyclonal
IgG
Rabbit
(undiluted serum, liquid, no preserve)
-
Human, Mouse, Rat
immunogen = synthetic peptide (N P T Y K Y L E Q M Q I) aa 752-763 at the C-terminus of mouse APLP2, coupled to KLH
APLP2; not APP or APLP1
-
APLP2, full length
Calbiochem EMD Biosciences
polyclonal
IgG
Rabbit
(undiluted serum, liquid, no preserve)
-
Human, Mouse, Rat
immunogen = full-length mouse APLP2
APLP2; not APP or APLP1
-
APP-CT20 /0443
Calbiochem EMD Biosciences
polyclonal
IgG
Rabbit
(liquid, undiluted serum, no preserve)
-
Human
immunogen = synthetic peptide (K M Q Q N G Y E N P T Y K F F E Q M Q N) at C-terminal region (aa 751-770) of human APP, conj. to KLH
detects C-terminal products CTFα (~9 kDa), CTFβ (~11 kDa) and CTFγ (~6 kDa) and full length APP
-
APP (3E9)
Calbiochem EMD Biosciences
monoclonal
IgG1
Mouse
(lyophilized, PBS, sucrose, azide, protein A purified)
-
Human
immunogen = synthetic peptide (L E V P T D G N A G L L A E P Q I A M F C) corresp. to aa 18-38 of human APP695
APP695 (~110-135 kDa)
-
APP Phos Thr668
Cell Signaling
polyclonal
Rabbit
(HEPES, NaCl, BSA, glycerol, Protein-A)
-
Human, Mouse, Rat
immunogen = synthetic peptide corresp. to residues surrounding Thr668 of human APP695, conj. to KLH
APP A4 when phosphorylated at Thr668 (position corresponding to APP695 isoform)
-
APP Phos Thr668
Cell Signaling
polyclonal
Rabbit
(HEPES, NaCl, BSA, glycerol, Protein-A)
-
Human, Mouse, Rat
immunogen = synthetic peptide corresp. to residues surrounding Thr668 of human APP695, conj. to KLH
detects different isoforms of endogenous amyloid β (A4) precursor protein only when phosphorylated at Thr668 (position corresponding to APP695 isoform)
-
APP, KPI domain (4.1)
Chemicon and Upstate are Millipore
monoclonal
IgG1
Mouse
(liquid, PBS, purified)
-
Human
immunogen = purified recombinant KPI domain of APP
APP, KPI domain (native and recombinant protein); partially inhibits protease inhibitory protein
-
APP, KPI domain
Chemicon and Upstate are Millipore
polyclonal
Rabbit
(serum, liquid, azide)
-
Human
immunogen = synthetic peptide corresp. to a part of KPI domain in soluble APP
soluble APP, KPI domain
-
APP (D3B10)
BioLegend
monoclonal
IgG1
Mouse
(purified, ascites, PBS, no preservatives or carrier proteins)
-
Human
Epitope lies within amino acids 61-77 of amyloid precursor protein
APP
Available from BioLegend
APP (1G6)
BioLegend
monoclonal
IgG1
Mouse
(purified, PBS, no preservatives or carrier proteins, biotinylated)
-
Human
Epitope lies within amino acids 573-596 of amyloid precursor protein
APP
Available from BioLegend
APP (LN27)
BioLegend
monoclonal
IgG1
Mouse
(liquid, protein G purified, no preservative)
-
-
-
recognizes all three known forms of APP (amyloid precursor protein), β-APP695, β-APP751 and β-APP770
Available from BioLegend
APPβ
None
kit
IgG1
Rabbit
-
Human, Mouse, Rat
immunogen = synthetic peptide corresp. to aa 573-596 of APP (amyloid precursor protein)
specific for the β isoform of sAPP (soluble amyloid precursor protein). It has negligible cross reactivity with β amyloid 40, 42, or sAPPα
Discontinued
APP (40.10)
Fitzgerald
monoclonal
IgM
Mouse
(lyophilized, supernatant, azide, affinity purified)
-
Human
immunogen = prokaryotic rh fusion protein corresp. to the extracellular portion of APP between the Kunitz protease inhibitor domain and the beta-amyloid region
APP
-
APP
Fitzgerald
polyclonal
Goat
-
-
immunogen = C-terminus of APP
APP C-terminus
-
APP frameshift mutant
Fitzgerald
polyclonal
Goat
-
-
immunogen = APP frameshift mutatant C-terminus
APP C-terminus, frameshift mutant
-
APP
Fitzgerald
polyclonal
Goat
-
-
immunogen = APP N-terminus
APP N-terminus,
-
APP, Frameshift mutant
Fitzgerald
polyclonal
Goat
(neat serum, no preservative)
-
Human
immunogen = synthetic peptide corresp. to aa 339-348 of the C-terminal APP frameshift mutant
C-terminus aa 339-348 of human APPFM
-
APP N-term
Fitzgerald
polyclonal
Goat
(liquid, neat serum, azide)
-
Human
immunogen = synthetic peptide equivalent to aa 44-63 of the N-terminus of human APP
APP N-terminus, residues 44-63
-
APP C-term
Fitzgerald
polyclonal
Goat
(neat serum, no preservative)
-
Human
immunogen = synthetic peptide corresp. to aa 681-695 on the C-terminal of APP
C-terminus aa 681-695 of human APP
-
APP
Fitzgerald
polyclonal
Goat
-
Human
-
APP
-
APP N-term
Fitzgerald
polyclonal
IgG
Goat
(neat serum, no preservative)
-
Human
immunogen = synthetic peptide corresp. to aa 44-63 on the N-terminus of APP
residues 44-63 on the N-terminus of APP
-
APP
Fitzgerald
polyclonal
Goat
-
-
-
APP
-
APP
Histo-Line
polyclonal
Goat
(liquid, neat serum, no preservatives)
-
Human
immunogen = synthetic peptide equivalent to aa681-695 of the C-terminal of human APP
APP C-terminal aa681-695
-
APP N-term
Histo-Line
polyclonal
IgG
Goat
(liquid, neat serum, no preservatives)
-
Human
immunogen = synthetic peptide equivalent to aa44-63 of the N-terminal of human APP
APP N-terminal aa44-63
-
APP frameshift mutant
Histo-Line
polyclonal
IgG
Goat
(liquid, neat serum, no preservatives)
-
Human
immunogen = synthetic peptide equivalent to aa339-348 of the C-terminal of human APP frameshift mutant
APP C-terminal aa339-348 of APPFM
-
β-APP (3G12)
Histo-Line
monoclonal
IgM
Mouse
(lyophilized, supernatant azide)
-
Human
immunogen = prokaryotic rh fusion protein corresp. to the extracellular protein of APP between the Kunitz protease inhibitor domain and the beta amyloid region
APP; no cross-reaction with APP-like proteins
-
APP (40.10)
Histo-Line
monoclonal
IgM
Mouse
(lyophilized, supernatant azide)
-
Human
immunogen = prokaryotic rh fusion protein corresp. to the extracellular protein of APP between the Kunitz protease inhibitor domain and the beta amyloid region
APP; no cross-reaction with APP-like proteins
-
sAPP
I B L-Hamburg GmbH
kit
IgG1
Unknown Host
(anti-mouse/rat APP; conj. anti-mouse/rat APP rabbit)
-
Mouse, Rat
-
sAPPα and full length APP
-
sAPPβ-sw (6A1)
I B L-Hamburg GmbH
monoclonal
IgG3
Mouse
(lyohilized, BSA, PBS, azide, supernatant protein-A purified)
-
Human
immunogen = synthetic peptide of the C-terminal part of human sAPPβ-sw (I S E V N L)
sAPPβ-sw type cleaved by β-secretase; no cross reaction with sAPPβ of wild type and the full length APP of both Swedish and wild types
-
sAPPβ-wild type
I B L-Hamburg GmbH
polyclonal
IgG
Rabbit
(lyophilized, BSA, PBS, azide, purified)
-
Human
immunogen = synthetic peptide in portion of C-terminus of human sAPPβ-Wild Type(I S E V K M)
detects sAPP-Wild type which is clevaged by β-secretase; no cross with sAPPα or full-length APP
-
sAPPα
I B L-Hamburg GmbH
polyclonal
IgG
Mouse
(lyophilized, BSA, PBS, azide, affinity purified)
-
Mouse, Rat
immunogen = synthetic peptide in portion of C-terminus of mouse/rat sAPPα (D A E F G H D S G F E V R H Q K)
detects sAPP-α; no cross-reaction with sAPPβ
-
sAPP
I B L-Hamburg GmbH
kit
Unknown Host
(mouse monoclonal anti-human APP; conj. anti-human sAPPα monoclonal mouse)
-
Human
-
detects soluble APP in samples as a total amount including sAPPα and sAPPβ
-
sAPPβ-wt
I B L-Hamburg GmbH
kit
Unknown Host
(rabbit polyclonal anti-human sAPPβ; conj. anti-human APP monoclonal mouse)
-
Human
-
detects soluble sAPPβ wild type
-
sAPPα
I B L-Hamburg GmbH
kit
Unknown Host
(mouse monoclonal anti-human sAPPα; conj. anti-human APP monoclonal mouse)
-
Human
-
detects soluble sAPPα
-
sAPPβ (Swedish type)
IBL
kit
Unknown Host
(96 well using 2 kinds of highly specific antibodies. Precoated plate with anti-Human sAPPβ-Swedish Type Rabbit IgG; labelled antibody HRP conjugated anti-Human APP (10D1) Mouse IgG Fab’)
-
Human
-
detects sAPPβ Swedish type in cell culture media
-
sAPPβ (wild type)
IBL
kit
Unknown Host
(96 well using 2 kinds of highly specific antibodies. Precoated plate with rabbit anti-Human sAPPβ-Wild Type; labeled antibody HRP conj. mouse anti-Human APP (10D1))
-
Human
-
detects sAPPβ wild type in cell culture media or cerebrospinal fluids.
-
APP βCTF
IBL
kit
IgG
Unknown Host
(Polyclonal rabbit anti-APP-C; monoclonal mouse anti-human Aβ(82E1))
-
Human
-
APP βCTF (β-secretase C-terminal fragment)
-
sAPP
IBL
kit
Unknown Host
(mouse monoclonal anti-human APP; conj. anti-human sAPPα monoclonal mouse)
-
Human
-
detects soluble APP in samples as a total amount including sAPPα and sAPPβ
-
sAPPα
IBL
kit
Unknown Host
(mouse monoclonal anti-human sAPPα; conj. anti-human APP monoclonal mouse)
-
Human
-
detects soluble sAPPα
-
APP (18)
IBL
polyclonal
IgG
Rabbit
(lyophilized, BSA, PBS, azide, affinity purified)
-
Human, Mouse, Rat
immunogen = synthetic peptide of a part of Human APP (L E V P T D G N A G L L A E P Q I A M F C)
detects APP; cross reacts with sAPPα and sAPPβ
-
APP (597)
IBL
polyclonal
IgG
Rabbit
(lyophilized, BSA, PBS, azide, affinity purified)
-
Mouse, Rat
immunogen = synthetic peptide in portion of C terminus of Mouse/Rat sAPPα(D A E F G H D S G F E V R H Q K)
detects APPα; no cross with sAPPβ
-
APP phosphorylated
IBL
polyclonal
IgG
Rabbit
(lyophilized, BSA, PBS, azide, affinity purified)
-
Human, Mouse
immunogen = synthetic peptide of phosphorylated part of APP(D A A V pT P E E)
detects phosphorylated APP; no cross with non phosphorylated APP
-
sAPP α (2B3)
IBL
monoclonal
IgG2b
Mouse
(lyophilized, BSA, PBS, azide, purified)
-
Human, Mouse, Rat
immunogen = synthetic peptide in portion of C-terminus of Human sAPPα(D A E F R H D S G Y E V H H Q K)
detects sAPPα; no cross with sAPPβ or full-length APP
-
sAPPß (swedish type) (6A1)
IBL
monoclonal
IgG3
Mouse
(supernatant, protein-A purified, BSA, PBS, azide, lyophilized)
-
Human
immunogen = synthetic peptide of the C-terminal part of human sAPPß-sw (I S E V N L)
specific for sAPPβ-sw type cleaved by β-secretase; no cross with sAPPβ-sw of wild type and the full length APP of both Swedish and wildtypes
-
APP pan
Leinco Technologies
polyclonal
Goat
(lyophilized, PBS, trehalose, no preservative, affinity purified)
-
Human
immunogen = SF21-derived + 1 frameshift mutant of APP695
APP pan
-
AβPP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(liquid, PBS, azide, affinity purified)
-
Porcine, Rabbit, Chicken, Human, Hamster, Mouse, Rat
immunogen = peptide seq. corresp. to aa653-662 of human amyloid A4 protein precursor (APP)
APP
-
AβPP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(liquid, KPBS, azide, affinity purified)
-
Human
immunogen = Beta amyloid peptide D-A-E-F-R-H-D-S-G-Y-E-V-H-H conjugated to KLH using maleimide. The sequence corresponds to aa 1-14 of human beta amyloid.
AβPP
-
AβPP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(liquid, antisera, azide)
-
Human, Mouse, Rat
immunogen = synthetic peptide corresp. to aa residues G L M V G G V V
AβPP
-
AβPP (J4H9)
LifeSpan Biosciences, Inc.
monoclonal
IgG2b , κ
Rabbit
(liquid, PBS, azide)
-
Human
immunogen = APP antibody was raised against recombinant human APP (18-289aa) purified from E. coli
APP
-
AβPP phosThr668
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(liquid, PBS, azide, glycerol, affinity purified)
-
Human
immunogen = synthetic peptide surrounding amino acid Thr 668 of human APP
AβPP
-
AβPP
LifeSpan Biosciences, Inc.
monoclonal
IgG2a
Mouse
(liquid, PBS, azide, protein A purified)
-
Human, Mouse, Rat
immunogen = Ni-NTA purified truncated recombinant APP expressed in E. coli strain BL21 (DE3)
truncated APP recombinant protein (WB), human APP recombinant protein (ELISA), human Alzheimer brain tissue (IHC)
-
AβPP phos Thr668
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(liquid, HEPES, NaCl, BSA, glycerol, affinity purified)
-
Human, Mouse, Rat
immunogen = synthetic phosphopeptide corresp. to residues surrounding Thr668 of human APP695 (KLH coupled)
APP when phos at Thr668
-
APP
LifeSpan Biosciences, Inc.
monoclonal
IgG2a , κ
Mouse
(liquid, IgG fract.)
-
Human
immunogen = synthetic peptide derived from the N-terminal region of human amyloid-b
APP (125kDa, mature and 110kDa immature); recognizes both the b'-cleavage-derived N-terminal ectodomain of APP (sAPPb') and the a-cleavage-derived N-terminal ectodomain of APP (sAPPa)
-
APP
LifeSpan Biosciences, Inc.
monoclonal
IgG2b
Mouse
(liquid, PBS, no preservative, protein A purified)
-
Human
immunogen = aa17-24 of beta amyloid
reacts with aa17-24 of human amyloid beta peptide (abnormally processed isoforms and precursor forms)
-
APP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(liquid, PBS, azide, affinity purified)
-
Human
immunogen = 30 aa synthetic peptide derived from the full length (1-43aa) β-Amyloid peptide
specific for the 4-5kD β-Amyloid peptide derived by cleavage from the β--Amyloid precursor protein
-
AβPP
Autogen Bioclear
polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
-
Human
immunogen = synthetic peptide corresp. to a protein sequence derived from N-terminus of human Amyloid Beta
recognizes human Amyloid Beta
-
AβPP (33D3)
LifeSpan Biosciences, Inc.
monoclonal
Mouse
(liquid, PBS, azide, protein G purified)
-
Human
immunogen = synthetic peptide corresp. to aa residues 1-16 of Aβ (β-amyloid) peptide
reacts with human Aβ peptide; epitope lies within aa residues 3-8 of β-amyloid (Aβ) peptide
-
APP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(liquid, PBS, no preservative, affinity purified)
-
Human
immunogen = synthetic peptide corresp. to aa1-40 of human β-Amyloid
β-Amyloid [1-40] in the region from aa 15-30; no blocking activity with β-Amyloid [1-12], whereas the peptides β-Amyloid [14-35], β-Amyloid [15-28] and β-Amyloid [17-30] were all able to block antibody activity as well as β-Amyloid [1-40]
-
APP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(liquid, PBS, azide, BSA, glycerol, affinity purified)
-
Human
immunogen = synthetic peptide consisting of 6 aa of human β1-42 within to the C-terminal, conj. to KLH
β-amyloid 42; minimal cross reactivity with β-amyloid 40
-
APP
LifeSpan Biosciences, Inc.
polyclonal
IgY
Chicken
(liquid, Tris, azide, glycerol, purified)
-
Human
immunogen = synthetic peptide corresp. to aa25-35 (NH2-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH) near the C-terminal of beta-Amyloid peptide (BSA coupled)
recognizes beta-Amyloid peptide aa 25-35
-
AβPP
LifeSpan Biosciences, Inc.
polyclonal
IgY
Chicken
(liquid, TBS, azide)
-
Bovine, Dog, Rabbit, Chicken, Zebra fish, Sheep, Pig, Human, Monkey, Guinea Pig, Hamster, Mouse, Rat, Xenopus, Cynomolgus
immunogen = synthetic peptide: G S N K G A I I G L M, corresp. to aa25-35 of human β-amyloid
recognizes β-
-
APP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(liquid, unpurified serum, azide, glycerol)
-
Human
immunogen = synthetic peptide consisting of 6aa of human β1-42 within to the C-terminal, conj. to KLH
β-amyloid 42; minimal cross reactivity with β-amyloid 40
-
APP
LifeSpan Biosciences, Inc.
polyclonal
IgY
Chicken
(liquid, Tris, glycerol, azide)
-
Avian (various), Human
immunogen = synthetic peptide corresp. to aa12-28 (NH2-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OH) near the C-terminal of Beta-Amyloid peptide (BSA coupled)
recognizes β-Amyloid peptide
-
AβPP
LifeSpan Biosciences, Inc.
polyclonal
IgY
Chicken
(liquid, TBS, azide)
-
Bovine, Dog, Rabbit, Chicken, Zebra fish, Sheep, Pig, Human, Monkey, Guinea Pig, Hamster, Mouse, Rat, Xenopus, Cynomolgus
immunogen = synthetic peptide: V H H Q K L V F F A E D V G S N K , corresp. to C- terminal aa12-28 of human β-amyloid, conj. to BSA
recognizes β-amyloid, peptide 12
-
APP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
-
Human, Mouse, Rat
immunogen = synthetic peptide from N-terminus of human APP
recognizes amyloid precursor protein
-
AβPP
Autogen Bioclear
polyclonal
IgG
Rabbit
(lyophilized, PBS, azide, affinity purified)
-
Human, Mouse, Rat
immunogen = synthetic peptide corresp. to aa32-40 of beta-Amyloid conjugated to KLH
APP
-
AβPP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(liquid, PBS, glycerol, BSA, thimerosal, affinity purified)
-
Human
immunogen = synthetic peptide mapping to the N-terminus of human beta-amyloid
detects 4-5 kDa human beta-Amyloid
-
AβPP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(liquid, PBS, glycerol, BSA, thimerosal, affinity purified)
-
Chicken, Human, Monkey, Mouse, Rat
-
APP
-
AβPP (33D3)
LifeSpan Biosciences, Inc.
monoclonal
IgG2b
Mouse
(liquid, PBS, no preservative, protein A purified)
-
Human, Mouse, Rat
immunogen = synthetic peptide corresp. to aa residues 17-24 of Aβ (β-amyloid) peptide
Aβ
-
AβPP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(lyophilized, unpurified serum)
-
Human, Mouse, Rat
immunogen = synthetic peptide as a part of Amyloid beta A4 protein
APP
-
AβPP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(liquid, HEPES, NaCl, BSA, glycerol, affinity purified)
-
Human, Monkey, Mouse, Rat
immunogen = peptide corresp. to residues surrounding Thr668 of human APP695
APP
-
AβPP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
-
Human
immunogen = synthetic peptide corresp. to the new C-terminus of caspase-cleaved amyloid precursor protein
recognizes caspase-generated neo epitope of APP
-
APP
LifeSpan Biosciences, Inc.
polyclonal
Rabbit
(DEAE-column chromatography)
-
Human, Mouse, Rat
immunogen = synthetic peptide corresp. to aa 737-751 of human amyloid precursor protein, seq. corresponds to aa 85-99 of the C99 fragment
recognizes both intact APP and the C99 fragment generated by Beta-secretase
-
AβPP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(liquid, neat serum, unpurified)
-
Yeast, Human
immunogen = synthetic molecular mimic of soluble oligomers
recognizes human β-amyloid, oligomer A11; recognizes all types of amyloid oligomers
-
AβPP
LifeSpan Biosciences, Inc.
polyclonal
Rabbit
(liquid, PBS, no preservative, affinity purified)
-
Human, Mouse, Rat
immunogen = synthetic peptide corresp. to aa1-40 of Aβ (β-amyloid) peptide
recognizes the sequence of Aβ [1-40] in the region from aa 15-30
-
AβPP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(liquid, serum, unpurified, azide)
-
Human
immunogen = C-terminal synthetic peptide (human) conjugated to KLH
reacts with Aβ [1-40] of amyloid plaques in AD brains
-
AβPP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
-
Human
-
-
-
AβPP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(lyophilized, serum, unpurified)
-
Mouse, Rat
immunogen = synthetic peptide (H M N V Q N G W K E S D P S G T K T C, aa: 44-62) as part of mouse APP isoform A conj. to the immunogenic protein blue carrier protein
APP
-
APP
LifeSpan Biosciences, Inc.
monoclonal
IgG1 , κ
Mouse
(liquid, PBS, azide, purified)
-
Human
immunogen = 28 aa synthetic peptide derived from the β-amyloid peptide
reacts with the 4-5kD b-amyloid peptide (βAP); high concentrations of antibody will also react with A-a, B-a and gamma subunits of fibrinogen
-
APP
LifeSpan Biosciences, Inc.
monoclonal
IgG1 , κ
Mouse
(liquid, PBS, azide, purified)
-
Human
immunogen = rh β-APP695
β-APP; recognizes an epitope within the first 200 amino acids in the β-APP N-terminus; react with all 3 forms
-
APP
LifeSpan Biosciences, Inc.
polyclonal
Goat
(unpurified serum)
-
Human
immunogen = peptide to the N-terminal region (aa 44-63) of the APP protein
APP
-
AβPP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Goat
(liquid, azide, unpurified serum)
-
Human
immunogen = synthetic peptide corresp. to the aa seq. 44-63 of human amyloid precursor protein
recognizes amyloid precursor protein (APP), 130 kDa
-
AβPP (1B11F3)
LifeSpan Biosciences, Inc.
monoclonal
IgG2a
Mouse
(liquid, ascites, PBS, azide)
-
Human
immunogen = ni-NTA purified truncated recombinant APP expressed in E. coli strain BL21
APP
-
APP
LifeSpan Biosciences, Inc.
monoclonal
IgG2a
Mouse
(liquid, PBS, BSA, azide, supernatant, purified)
-
Human
immunogen = human serum amyloid A (APO SAA)
reacts with amyloid A, serum; useful for the detection of AA-type amyloid and for the discrimination from other type of amyloid (AL-type and b2M-amyloid)
-
AβPP (8J263)
LifeSpan Biosciences, Inc.
monoclonal
IgG2a
Mouse
(liquid, supernatant)
-
Human, Rat
immunogen = human serum amyloid A (Apo-SAA)
reacts with AA-type Amyloid depositions
-
APP
LifeSpan Biosciences, Inc.
monoclonal
IgG1
Mouse
(PBS, azide, BSA, IgG fract, purified)
-
Human
immunogen = human SAA and helix pomatia haemocyanine
reacts with all known SAA types
-
AβPP (8J262)
LifeSpan Biosciences, Inc.
monoclonal
IgG1
Rabbit
(liquid, PBS, BSA, azide, protein G purified)
-
Human
immunogen = human SAA and helix pomatia hemocyanin
reacts with all known SAA types
-
APP
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(unpurified serum, no preservative)
-
Human
immunogen = APP, KPI Domain
Amyloid Precursor Protein (APP), KPI Domain
-
AβPP (Y188)
LifeSpan Biosciences, Inc.
monoclonal
IgG
Rabbit
(liquid, Tris-glycine, NaCl, supernatant, azide, glycerol)
-
Human, Mouse, Rat
immunogen = synthetic peptide corresp. to residues in the NPXY motif of human Amyloid Beta A4 precursor (APP)
recognizes APP and its isoforms; not either of the two amyloid beta protein (Abeta4) variants, Abeta 1-40 or Abeta 1-42
-
AβPP phos Thr668
LifeSpan Biosciences, Inc.
polyclonal
IgG
Rabbit
(liquid, BSA, HEPES, NaCl, glycerol)
-
Human, Mouse, Rat
immunogen = synthetic peptide (human) corresp. to residues surrounding Thr668 conj. to KLH
detects different isoforms of endogenous amyloid beta (A4) precursor protein only when phosphorylated at Thr668 (position corresponds to APP695 isoform)
-
APP phos Thr668
LifeSpan Biosciences, Inc.
polyclonal
Rabbit
(liquid, PBS, affinity purified, no preservative, no glycerol)
-
Human, Mouse, Rat
immunogen = synthetic phospho-peptide (KLH coupled) corresp. to residues surrounding Thr668 of human APP695
detects different isoforms of amyloid beta (A4) precursor protein only when phosphorylated at Thr668 (position corresponds to APP695 isoform)
-