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Antibodies

778 Results

Name Source Clonality &
Isotype
Host &
Formulation
Method Reactivity Immunogen/
Epitope
Specificity Availability
APP, APLP, AICD From labs (4)
36BO(X Tian et al., 2007Paper, Subcell Biochem)Laboratory of Michael PrzybylskiSee paper on Mass spectrometric approaches for elucidation of antigen /antibody recognition structures polyclonal
Rabbit
IH, IP, WB Human immunogen = recomb. GST-C-APP fusion protein [724–770]. (epitope at aa. 727-737) Epitope determined by epitope excision /extraction -mass spectrometry. Similar differential epitope identification process identified the epitope of the Jonas-mAb as aa. 740-747, including the potential Caspase-3 cleavage site recognizes APP, C-terminal, intracellular doman. Thepolyclonal cAPP antibody 36BO can be used for detecting full length APP and largeC-terminal APP fragments, while the monoclonal Jonas-mAb should be a useful toolfor the study of APP processing in apoptotic neuronal cells and in brain extracts -
Edward Koo monoclonal
Mouse
(affinity purified)
IP Human immunogen = C-terminally truncated secreted βAPP derivatives purified from conditioned medium of βAPP-transfected CHO cells in Freund’s adjuvant recognizes the mid-region of the APP ectodomain -
(Dr. Edward Koo, University of California, San Diego)Paper monoclonal
Mouse
IF, IP Human, Mouse immunogen = human APPs purified from APP-transfected CHO cells (epitope between aa 380 and 365, in the extracellular region) recognizes an APP surface domain, excluding both the KPI and Aβ domains -
APPNeo(Dr. Dale Bredesen, Buck Institute for Age Research)Paper,PaperReference: Banwait, 2008 polyclonal
Rabbit
(affinity purified, borate buffer)
ELISA, IP, WB Human, Mouse immunogen = the peptide 657CIHHGVVEVD664, which includes the nine amino acids immediately preceding the caspase cleavage site at position 664 in AβPP, coupled to KLH recognizes the neo-epitope generated by cleavage of AβPP at Asp664 in its intracellular, C-terminal domain; recognizes APP that was truncated at Asp664 but not intactAPP -
APP, APLP, AICD From manufacturers (96)
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(liquid, serum)
ELISA, IC, IH, IP Human, Monkey immunogen = nine aa peptide from the C-terminus of APP APP C-terminal; may react with APLP1 and APLP2 -
LifeSpan Biosciences, Inc. monoclonal
Mouse
(protein G purified)
ELISA, IH, IP, WB Human, Monkey immunogen = aa residues 1-17 of human beta Amyloid; Epitope is within aa 4-9 (F R H D S G) APP; reacts to abnormally processed isoforms as well as precursor forms -
LifeSpan Biosciences, Inc. monoclonal
Mouse
(protein G purified)
ELISA, IH, IP, WB Human immunogen = synthetic peptide corresp. to aa 1-16 of beta-amyloid peptide; epitope lies within aa residues 3-8 of beta-amyloid peptide beta-Amyloid peptide -
LifeSpan Biosciences, Inc. monoclonal
Mouse
(protein A purified)
ELISA, IH, IP, WB Human, Mouse, Rat immunogen = synthetic peptide corresp. to aa17-24 of beta-amyloid peptide beta-Amyloid peptide -
LifeSpan Biosciences, Inc. polyclonal
Goat
(liquid, serum)
ELISA, IF, IH, WB Human immunogen = synthetic 20-aa peptide near the extracellular, N-terminus (44-63 aa) of human APP695, conj. to KLH all major APP isoforms (APP695, APP751 and APP770) -
LifeSpan Biosciences, Inc. polyclonal
Goat
(unpurified serum)
ELISA, IH, WB Human immunogen = synthetic peptide: H M N V Q N G K W D S D P S G T K T C I (aa 44-63) of the N-terminal of human APP APP and the cleaved N-terminal APP fragments -
LifeSpan Biosciences, Inc. monoclonal
Mouse
(protein A purified)
ELISA, IF, IH Human immunogen = human serum Amyloid A (Apo-SAA) recognizes serum Amyloid A; reacts with AA-type Amyloid depositions. -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(DEAE-column chromatography)
ELISA, RIA, WB Human immunogen = beta amyloid peptide, D A E F R H D S G Y E V H H, conj. to KLH using maleimide ( aa 1-14 of human beta amyloid) recognizes b-Amyloid, NT -
LifeSpan Biosciences, Inc. monoclonal
Mouse
ELISA, IC, WB Human immunogen = synthetic peptide corresp. to a portion of N-terminal of human -amyloid recognizes the free N-terminus of amyloid A4 as well as APP (amyloid precursor protein) -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(protein A purified)
ELISA, IC, IH, IP Human, Mouse, Rat immunogen = synthetic phospho-peptide (KLH coupled) corresp. to residues surrounding Thr668 of human APP695 APP Thr668 -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(protein A purified)
ELISA, IH, WB Human, Monkey immunogen = synthetic phospho-peptide (KLH coupled) corresp. to residues surrounding Thr668 of human APP695 APP Thr668 -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(DEAE-column chromatography)
ELISA, IH, WB Human, Mouse, Rat immunogen = synthetic peptide corresponding to N-terminal of human APP recognizes APP (b-APP770), MW 110kD. Predicted to recognize b-APP695 and b-APP751 -
LifeSpan Biosciences, Inc. polyclonal
Goat
(unpurified serum)
ELISA, IH, WB Human immunogen = synthetic peptide, corresp. to aa 339-348 of the C-terminal human APP frameshift mutant recognizes APP frameshift mutant; labels dystrophic neurites in senile plaques and shows immuno-reactivity with neurons containing the APPFM protein -
LifeSpan Biosciences, Inc. polyclonal
Goat
(unpurified serum)
ELISA, IH, WB Human immunogen = synthetic peptide corresp. to aa 339-348 of the C-terminal region of the human Alzheimer's APP Frameshift Mutant APP frameshift mutant (APPFM) -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(unpurified serum)
IH, IP, WB Human immunogen = synthetic peptide from C-terminus of APP recognizes an epitope at the C-terminus of APP -
LifeSpan Biosciences, Inc. monoclonal
Mouse
ELISA, IC, WB Human immunogen = synthetic peptide corresp. to a portion of N-terminal of human -amyloid recognizes the free N-terminal amyloid -
LifeSpan Biosciences, Inc. monoclonal
Mouse
ELISA, IC, WB Human immunogen = synthetic peptide corresp. to a portion of N-terminal of human -amyloid recognizes the free N-terminal amyloid -
LifeSpan Biosciences, Inc. monoclonal
Mouse
ELISA, IC, WB Human immunogen = synthetic peptide corresp. to aa 1-40 of C-terminal human -amyloid recognizes the C-terminus of beta-amyloid (aa 1-40 isoform); no cross-reaction with beta-amyloid (aa 1-42 isoform) -
LifeSpan Biosciences, Inc. monoclonal
Mouse
(DEAE-column chromatography)
ELISA, IC, WB Human immunogen = C-terminal peptide of human beta-amyloid (KLH coupled) recognizes the C-terminus of beta-amyloid (aa 1-40 isoform); no cross-reaction with beta-amyloid (aa 1-42 isoform) -
LifeSpan Biosciences, Inc. monoclonal
Mouse
ELISA, IC, WB Human immunogen = synthetic peptide corresp. to aa 1-40 of C-terminal human -amyloid recognizes the C-terminus of beta-amyloid (aa 1-40 isoform); no cross-reaction with beta-amyloid (aa 1-42 isoform) -
LifeSpan Biosciences, Inc. monoclonal
Mouse
ELISA, IC, WB Human immunogen = synthetic peptide corresp. to N-terminal human -amyloid recognizes the free N-terminus of human -amyloid A4 as well as APP (amyloid precursor protein). -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(DEAE-column chromatogaphy)
DB, ELISA, RIA, WB Human immunogen = synthetic peptide (5-10 aa) ending at cleavage site 42 recognizes β-amyloid 1-42. No significant cross reactivity of β-amyloid 1-40 or 1-43. -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(unpurified serum)
DB, ELISA, RIA, WB Human - recognizes β-amyloid 1-43; no significant cross reactivity of β-amyloid 1-40 or 1-42 -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(DEAE-column chromatogaphy; biotinylated)
DB, ELISA, RIA, WB Human immunogen = synthetic peptide (5-10 aa) that ends at cleavage site 40 recognizes β-amyloid 1-40; no significant cross-reactivity against β-amyloid 1-42 or 1-43 -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(unpurified serum)
DB, ELISA, RIA, WB Human, Mouse, Rat immunogen = β--amyloid 42 protein recognizes β-amyloid 1-42; no significant cross-reactivity against β-amyloid 1-40 or 1-43 -
LifeSpan Biosciences, Inc. monoclonal
Mouse
ELISA, IC, WB Human immunogen = synthetic peptide recognizes -amyloid aa 1-43 isoform; no cross-reaction with -amyloid aa 1-40 or aa 1-42 isoforms -
LifeSpan Biosciences, Inc. monoclonal
Mouse
ELISA, IC, WB Human immunogen = synthetic peptide corresp. to aa 1-40 and aa 1-42 of C-terminal human -amyloid APP -
LifeSpan Biosciences, Inc. monoclonal
Mouse
ELISA, IC, WB Human immunogen = synthetic peptide corresp. to aa 1-40 and aa 1-42 of C-terminal human -amyloid APP -
LifeSpan Biosciences, Inc. monoclonal
Mouse
ELISA, IC, WB Human immunogen = synthetic peptide corresp. to aa 1-40 and aa 1-42 of C-terminal human -amyloid APP -
LifeSpan Biosciences, Inc. monoclonal
Mouse
ELISA, IC, WB Human immunogen = synthetic peptide corresp. to aa1-42 of C-terminal human b-amyloid (KLH) APP -
LifeSpan Biosciences, Inc. monoclonal
Mouse
(biotinylated)
ELISA, IC, WB Human immunogen = synthetic peptide corresp. to aa1-42 of C-terminal human b-amyloid (KLH) recognizes the C-terminus of -amyloid aa 1-42 isoform; no cross-react with -amyloid aa 1-40 isoform -
LifeSpan Biosciences, Inc. monoclonal
Mouse
ELISA, IC, WB Human immunogen = a 28 amino acid synthetic peptide derived from the β-amyloid peptide reacts with the 4-5kD β-amyloid peptide (β-AP). High concentrations of antibody will also react with A-a, B-a and γ subunits of fibrinogen -
LifeSpan Biosciences, Inc. monoclonal
Mouse
(FITC)
ELISA, IC, WB Human immunogen = synthetic peptide corresp. to aa1-42 of C-terminal human b-amyloid recognizes the C-terminus of -amyloid aa 1-42 isoform; no cross-react with -amyloid aa 1-40 isoform -
LifeSpan Biosciences, Inc. monoclonal
Mouse
(protein G purified)
IC, IP, WB Human immunogen = synthetic peptide consisting of residues 1 - 17 of the amyloid beta protein recognizes the human beta amyloid peptide -
LifeSpan Biosciences, Inc. polyclonal
Goat
(liquid, unpurified serum)
ELISA, IH, WB Human immunogen = a synthetic peptide corresp. to aa sequence 339-348 (339R G R T S S K E L A348) of the C-terminus of human amyloid precursor protein frameshift mutant recognizes the APP frameshift mutant (APPFM), a protein with Mr45kD. -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(liquid, PBS, azide, affinity purified)
IH, WB Human, Mouse, Rat immunogen = synthetic peptide corresp. to aa 737-751 of human amyloid A4 protein precursor (APP) or 85 to 99 of the C99 fragment generated by β-secretase cleavage APP -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(liquid, PBS, azide, affinity purified)
IH, WB Human, Mouse, Rat immunogen = synthetic peptide corresp. to aa of human amyloid A4 protein precursor (APP) corresp. to the N-terminus of the 4K Aβ peptide generated by β- and γ-secretases APP -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
IP, WB Human, Mouse, Rat immunogen = synthetic peptide corresp. to aa residues G L M V G G V V APP -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
IP, WB Human, Mouse, Rat immunogen = synthetic whole peptide APP -
LifeSpan Biosciences, Inc. polyclonal
Goat
(liquid, unpurified serum)
ELISA, WB Human immunogen = synthetic peptide of human APP, G Y E N P T Y K F F E Q M Q N (aa 681-695) APP aa 681-695 -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(liquid, unpurified serum)
ELISA, WB Human immunogen = synthetic peptide from the C-terminus of human Amyloid Precursor Protein recognizes the immature APP, a protein with Mr95kD and also the APP holoprotein, a post translationally modified protein with Mr100-120kD. Crossreacts with Amyloid Precursor-Like Protein 1 (APLP1) (~66kD). -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(liquid, protein A purified)
ELISA, WB Human, Mouse, Rat immunogen = synthetic peptide from the extreme C-terminus of human amyloid A4 protein precursor recognizes amyloid A4 protein precursor. -
LifeSpan Biosciences, Inc. polyclonal
Goat
(liquid, unpurified serum)
ELISA, WB Human immunogen = synthetic 15-aa peptide near the C-terminus of human APP695 (606-620 aa), conj. to KLH APP -
LifeSpan Biosciences, Inc. polyclonal
Goat
(liquid, unpurified serum)
ELISA, WB Human immunogen = synthetic peptide corresp. to aa 681-695 at the C-terminus of APP Recognizes amyloid precursor protein -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(liquid, unpurified serum)
ELISA, WB Human immunogen = synthetic peptide that corresponds to a part of KPI domain in soluble APP recognizes amyloid precursor protein -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(liquid, unpurified serum)
IP, WB Human immunogen = highly purified antigen recognizes amyloid precursor protein -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(liquid, DEAE- column chromatography)
EMSA, WB Human immunogen = synthetic peptide that corresponds to a part of KPI domain in soluble APP recognizes soluable APP and synthetic peptide corresp. to a part of KPI domain in soluble APP by ELISA -
LifeSpan Biosciences, Inc. polyclonal
Goat
(liquid, unpurified serum)
IH, WB Human immunogen = synthetic peptide corresp. to aa 339-348 of the C-terminus of APP frameshift mutant APP frameshift mutant -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(liquid, IgG fract.)
IH, WB Human, Mouse, Rat immunogen = synthetic peptide corresp. to aa 653-662 of human APP or 1-10 of the beta amyloid peptide recognizes both intact APP and the 4kD beta amyloid peptide that is generated by the action of beta and gamma secretases -
LifeSpan Biosciences, Inc. polyclonal
Chicken
ELISA, WB Human immunogen = purified ABCG1_extra recombinant protein (120kD) from human chromosome 21 APP extra -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(unpurified serum)
ELISA, WB Human immunogen = synthetic peptide corres.ponding to aa sequence 681-695 (G Y E N P T Y K F F E Q M Q N) of the C-terminus of human Amyloid Precursor Protein APP; may cross react with APLP2 -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(DEAE-column chromatography)
EMSA, IH Human immunogen = synthetic peptide from aa 8-17 of human amyloid beta-protein recognizes Amyloid beta -
LifeSpan Biosciences, Inc. monoclonal
Mouse
(DEAE-column chromatography)
ELISA, WB Human immunogen = amyloid precursor protein (APP) secreted by the EJ-1 bladder carcinoma cell line recognizes secretory amyloid precursor protein (sAPP); no cross reaction with amyloid-beta protein 1-40 -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(unpurified serum)
IP, WB Human, Monkey immunogen = APP (aa 99-126) conjugated to KLH recognizes the immature APP, a protein with Mr95kD and also the APP holoprotein, a posttranslationally modified protein with Mr100-120kD; specific to aa 99-126. -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(unpurified serum)
ELISA, WB Human immunogen = synthetic peptide of amyloid-β protein 1-40 recognizes amyloid-beta protein 1-40 (βAP), but not with either βAP 17-42 or secretory amyloid precursor protein -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(unpurified serum)
ELISA, IH Human immunogen = synthetic peptide corresp. to aa1-14 (D A E F R H D S G Y E V H H) of human amyloid beta recognizes aa1-14 of amyloid beta -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(unpurified serum)
ELISA, IH Human immunogen = synthetic peptide corresp. to aa1-14 (D A E F R H D S G Y E V H H) of human amyloid beta protein recognizes aa1-14 of amyloid beta -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(DEAE-column chromatography)
ELISA, IH Human, Mouse immunogen = synthetic peptide of human beta amyloid 1-40 synthetic C-terminal 7 aa peptide, conj. to KLH β-amyloid (1-40) and β-amyloid (1-42). Weak cross-reactivity is observed with β-amyloid (1-28) and β-amyloid (12-28). no cross-reaction is observed with CGRP -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(unpurified serum)
ELISA, WB Human, Mouse immunogen = synthetic peptide of human beta amyloid 1-40 synthetic C-terminal 7 aa peptide, conj. to KLH β-amyloid; high degree of homology with β-amyloid (1-40) and β-amyloid (1-42). Weak cross-reactivity with β-amyloid (1-28) and β-amyloid (12-28). No cross-reaction is observed with CGRP. -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(unpurified serum)
ELISA, WB Human, Mouse immunogen = synthetic β-1-40 conjugated to BSA β-1-40 and β-1-42; weak cross-reactivity is observed with β-1-28 and β-12-28; no cross-reactivity is observed with CGRP -
LifeSpan Biosciences, Inc. polyclonal
Goat
(unpurified serum)
ELISA, WB Human immunogen = synthetic peptide corresp. to β-1-40/42 conjugated to KLH βamyloid-1-40 /42 -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(ion exchange chromatography purified)
IH, WB Human immunogen = synthetic peptide Tg conj. stains senile plaques in brain sections of Alzheimer patients. -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(unpurified serum)
IP, WB Human, Monkey immunogen = highly purified antigen recognizes an epitope within the OX-2 domain of the human amyloid precursor protein (APP) -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(DEAE-column chromatography)
WB Human, Mouse, Rat immunogen = synthetic peptide seq. corresp. to aa 653 to 662 of human amyloid A4 protein precursor (APP) APP -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(protein G purified)
WB Human, Mouse, Rat immunogen = synthetic peptide corresp. to aa 653-662 (R P G S G L T N I K) of human amyloid precursor protein, KLH conj. APP -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(DEAE-column chromatography)
WB Human, Mouse, Rat immunogen = synthetic peptide corresp. to residues 756-770 of the full length human APP protein or to residues 85-99 in the human C99 fragment generated by beta-secretase cleavage recognizes both intact APP and the C99 fragment generated by Beta-secretase -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(Protein G purified)
WB Human, Mouse, Rat immunogen = peptide corresp. to aa 653-662 of human amyloid A4 protein precursor (APP) or aa 1-10 of the 4K Aβ peptide generated by β- and γ-secretases recognizes both intact APP and the C99 fragment generated by Beta-secretase -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(Protein G purified)
WB Human, Mouse, Rat immunogen = synthetic peptide corresp. to aa residues 737-751 of human amyloid A4 protein precursor (APP) or residues 85-99 of the C99 fragment generated by B-secretase cleavage APP -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(IgG fract.)
WB Human, Mouse, Rat immunogen = synthetic peptide corresp. to aa residues 653-662 of human amyloid A4 protein precursor (APP) or residues 1-10 of the 4kD peptide generated by β- and δ secretases APP (A alpha NT) -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(DEAE-column chromatography)
WB Human, Mouse, Rat immunogen = synthetic peptide corresp. to aa residues 737-751 of human amyloid A4 protein precursor (APP) or residues 85-99 of the C99 frag. generated by β- secretase cleavage APP (CT) and C99 fragment -
LifeSpan Biosciences, Inc. monoclonal
Mouse
WB Human, Rat immunogen = synthetic peptide Alz 90 (aa 511-608 of amyloid precursor protein pre A4695) natural amyloid precursor protein A4695 -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(unpurified serum)
ELISA Human immunogen = synthetic peptide of amyloid-beta protein 17-42 recognizes amyloid-beta protein 17-42 (b-AP) and b-AP 1-40; no reaction with secretory amyloid precursor protein (sAPP) -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(unpurified serum)
DB, ELISA, RIA Human - APP -
LifeSpan Biosciences, Inc. polyclonal
Rabbit
(unpurified serum)
DB, ELISA, RIA Bovine, Dog, Rabbit, Frog, Polar Bear, Sheep, Pig, Human, Mouse, Rat immunogen = synthetic peptide corresp. to the N-terminus of the human A 40 cleavage site A40; no cross-reactivity to A42 -
LifeSpan Biosciences, Inc. monoclonal
Mouse
(ascites)
WB Human, Mouse immunogen = synthetic peptide corresponding to amino acids 37-43 of human amyloid bx-43 peptide, conj. KLH recognizes amyloid bx-43 polypeptide, Mr 4.5kD -
LifeSpan Biosciences, Inc. monoclonal
Mouse
(protein A purified)
ELISA Human immunogen = Amyloid β-peptide (5-16) coupled to carrier the binding of this antibody to amyloid β-peptide depends on the presence of at least aa residues 10-16 -
LifeSpan Biosciences, Inc. monoclonal
Mouse
(protein A purified)
ELISA Human immunogen = Amyloid β-peptide (5-16) coupled to carrier the binding of this antibody to amyloid β-peptide depends on the presence of at least aa residues 9-10 -
LifeSpan Biosciences, Inc. monoclonal
Mouse
(protein A purified)
ELISA Human immunogen = Amyloid β-peptide (5-16) coupled to carrier the binding of this antibody to amyloid β-peptide depends on the presence of at least aa residues 5-9 -
LifeSpan Biosciences, Inc. monoclonal
Mouse
(protein A purified)
ELISA Human immunogen = Amyloid β-peptide (5-16) coupled to carrier the binding of this antibody to amyloid β-peptide depends on the presence of at least aa residues 10-16 -
LifeSpan Biosciences, Inc. polyclonal
Goat
- Human - APP -
LifeSpan Biosciences, Inc. monoclonal
Mouse
(IgG fract.)
- Human immunogen = 21-aa synthetic peptide within the extracellular (18-38 aa), N-terminus of human APP695 - -
Chemicon and Upstate are Millipore monoclonal
IgG1
Mouse
(liquid, PBS, azide, purified)
ELISA, IH, WB Human immunogen = purified recombinant KPI domain of AβPP AβPP, KPI (Kunitz protease inhibitor) domain; native and recombinant -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(liquid, PBS, BSA, glycerol, azide, affinity purified)
WB Human immunogen = synthetic peptide of aa surrounding the phospho Threonine 668 site of human APP695 APP (Alzheimer's precursor protein) phosphoThreonine 668 -
Chemicon and Upstate are Millipore polyclonal
Goat
(liquid, antiserum, PBS, thimerosal)
ELISA, IF, IH Human immunogen = peptide to the N-terminal region (aa 44-63) of APP APP in dystrophic neurites in senile plaques -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(liquid, serum, PBS, azide)
IC, IP, WB Human, Monkey, Mouse immunogen = APP (aa 99-126), conj. to KLH APP specific to aa 99-126 -
Chemicon and Upstate are Millipore monoclonal
IgG1
Mouse
(liquid, PBS, tween 20, proClin 300, prediluted)
IH Fish (various), Dog, Pig, Human, Monkey, Mouse, Rat immunogen = purified recombinant alzheimer precursor A4 fusion protein recognizes all three isoforms of APP immature ~110kDa, sAPP ~120kDa and mature ~130kDa; cross reacts with APLP2 -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
IH, WB Human, Rat immunogen = synthetic peptide corresp. to the new C-terminus of caspase-cleaved APP Caspase-generated neo epitope of APP -
Chemicon and Upstate are Millipore polyclonal
Goat
(liquid, serum, thimerosal)
ELISA, IH, WB Human immunogen = synthetic peptide corresp. to aa 339-348 of the C-terminal region of human APP Frameshift Mutant, APP Frameshift Mutant -
RDI /Fitzgerald monoclonal
IgG1
Mouse
(purified, lyophilized)
IH, WB Human, Rat immunogen = carboxy fragment APP 643-695/Jonas full-length APP and selectively with the cytoplasmatic carboxyl fragment of APP 643-695 -
Abcam monoclonal
IgG1
Mouse
(liquid, protein-G purified, PBS, Thimerosal)
ELISA, IH, IP, WB Human immunogen = synthetic peptide, corresp. to aa 1-17 of human β-Amyloid, with Glu substituted at position 11, conj. to KLH recognizes beta amyloid peptide, the precursor and the abnormally processed isoforms -
Upstate and Chemicon are Millipore polyclonal
IgG
Rabbit
(liquid, tris-glycine saline, glycerol, azide, affinity purified)
IP, WB Human, Rat immunogen = synthetic peptide (H M N V Q N G K W D S D P S G T K T) corresp. to aa 44-61 of human APP APP (110 kDa) -
Upstate and Chemicon are Millipore polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
WB Dog, Chicken, Human, Mouse, Rat immunogen = synthetic peptide corresp. to aa 663-674 (V D A A V[pT]P E E R H L) of human AβPP, isoform c, KLH-conjugated APP phosphorylated onThreonine 668 -
Chemicon and Upstate are Millipore monoclonal
IgG2a
Mouse
(liquid, PBS, azide, affinity purified)
ELISA, WB Human APP secreted by the EJ-1 bladder carcinoma cell line secretory APP and not Aβ 1-40 -
I B L - Hamburg GmbH polyclonal
IgG
Rabbit
(lyophilized, BSA, PBS, azide, purified)
IP, WB Human, Mouse, Rat immunogen = synthetic peptide in portion of C-terminus of Human APP detects all isoforms (APP695, APP751, APP770); no cross with sAPPα or sAPPβ -
I B L - Hamburg GmbH monoclonal
IgG1
Mouse
(lyophilized, BSA, PBS, azide, protein-A purified)
IP, WB Human, Mouse immunogen = N-terminal portion of recomb. Human APP detects all isoforms (APP695, APP751, APP770 and soluble APP (sAPPα and sAPPβ) -
Lab Vision Thermo Scientific polyclonal
Rabbit
(liquid, PBS, BSA, azide, affinity purified; or prediluted, ready to use)
IH, WB Human, Mouse, Rat immunogen = synthetic peptide corr. to N terminal of human APP β-APP770 (110 kDa); predicted to recognize β-APP695 and β-APP771 -