|
|
Edward Koo |
monoclonal
|
Unknown Host
|
WB |
- |
- |
β-amyloid |
- |
|
|
amyloid beta 12B4(Frederique Bard,Elan Pharma- ceuticals, So. San Francisco, CA)Reference: Bard, 2003 |
monoclonal
|
Unknown Host
(supernat, RIA screened, HPLC purified) |
IH, WB |
- |
immunogen = synthetic peptide fragment derived from different regions of amyloid-beta and coupled to a carrier protein |
amyloid-beta |
- |
|
|
amyloid beta 2C1(Frederique Bard,Elan Pharma- ceuticals, So. San Francisco, CA)Reference: Bard, 2003 |
monoclonal
|
Mouse
(supernat, RIA screened, HPLC purified) |
IH, WB |
- |
immunogen = synthetic peptide fragment derived from different regions of amyloid-beta and coupled to a carrier protein |
amyloid-beta |
- |
|
|
amyloid beta 12A11(Frederique Bard,Elan Pharma- ceuticals, So. San Francisco, CA)Reference: Bard, 2003 |
monoclonal
|
Unknown Host
(supernat, RIA screened, HPLC purified) |
IH, WB |
- |
immunogen = synthetic peptide fragment derived from different regions of amyloid-beta and coupled to a carrier protein |
amyloid-beta |
- |
|
|
Aβ-42 EL26(Frederique Bard,Elan Pharma- ceuticals, So. San Francisco, CA)Reference: Bard, 2003 |
monoclonal
|
Unknown Host
|
IH |
- |
immunogen = amyloid beta (7-1)-42; epitope = aa 11-26 |
amyloid-beta |
- |
|
|
anti-amyloid beta(Paul Gottschall,Univ South Florida Col of Med. Dept of Pharmacology & Therapeutics, Tampa, FL)Reference: Jantzen, 2002 |
monoclonal
|
Unknown Host
|
- |
- |
|
amyloid-beta |
- |
|
|
C. Masters |
monoclonal
|
Unknown Host
|
IH |
- |
amyloid-β 86/31 |
- |
- |
|
|
H. Mori |
unknown
|
Unknown Host
|
- |
- |
- |
total amyloid-beta 42 |
- |
|
|
amyloid-beta 40(H. Mori)Reference: Guo J, 2006 |
unknown
|
Unknown Host
|
- |
- |
|
total amyloid-beta 40 |
- |
|
|
R17 amyloid-beta 1-23(T Ishii)Reference: Guo J, 2006 |
polyclonal
|
Rabbit
|
- |
- |
|
- |
- |
|
|
PFA1(lab of Chris Dealwis,Univ. of Tennessee, Knoxville, TN)Reference: Gardberg, 2007 |
monoclonal
IgG2 |
Mouse
(liquid, protein-A affinity purified) |
ELISA |
Human |
immunogen = CLC-stabilized protofibril form of Aβ(1–40); epitope within Aβ(1–8); DAEFRHDS, at the N terminus |
The Fab fragments exhibit bindingto Aβ monomers in the 20–40 nM range, and this binding issignificantly impaired or eliminated in Aβ(1–40) mutants inwhich a single residue in the 3–7 segment is replaced withalanine. The full IgG molecules bind significantly better than Fabfragments to Aβ fibrils and protofibrils (0.1–0.2 nM); PFA1 binds more tightly to fibrils than doesPFA2. diminished affinity forpyroglutamate-Glu forms of Aβ |
- |
|
|
PFA2(lab of Chris Dealwis,Univ. of Tennessee, Knoxville, TN)Reference: Gardberg, 2007 |
monoclonal
IgG2 |
Mouse
(liquid, protein-A affinity purified) |
ELISA |
Human |
immunogen = CLC-stabilized protofibril form of Aβ(1–40); epitope within Aβ(1–8); DAEFRHDS, at the N terminus |
The Fab fragments exhibit bindingto Aβ monomers in the 20–40 nM range, and this binding issignificantly impaired or eliminated in Aβ(1–40) mutants inwhich a single residue in the 3–7 segment is replaced withalanine. The full IgG molecules bind significantly better than Fabfragments to Aβ fibrils and protofibrils (0.1–0.2 nM); PFA1 binds more tightly to fibrils than doesPFA2. diminished affinity forpyroglutamate-Glu forms of Aβ |
- |
|
|
Innovex Biosciences |
monoclonal
|
Mouse
(concentrate) |
- |
- |
|
|
- |
|
|
Biotrend |
kit
|
|
IF |
- |
|
Amyloid beta |
- |
|
|
Biotrend |
polyclonal
|
Rabbit
(Ig fraction) |
- |
Human |
|
|
- |
|
|
Biotrend |
polyclonal
|
Rabbit
(Ig fraction) |
- |
Human |
|
Amyloid beta, N-terminal |
- |
|
|
Biotrend |
monoclonal
IgG1 |
Mouse
(Ig fraction) |
IH |
Human |
|
|
- |
|
|
Biotrend |
polyclonal
|
Rabbit
(Ig fraction) |
- |
Human |
|
|
- |
|
|
Biotrend |
monoclonal
IgG1 |
Mouse
(Ig fraction) |
IH |
Human |
|
|
- |
|
|
Innovex Biosciences |
monoclonal
|
Mouse
(pretitered) |
- |
- |
- |
|
- |
|
|
Accurate |
monoclonal
IgG1κ |
Mouse
(supernatant) |
IH |
Human |
8-17, synthetic |
|
- |
|
|
Accurate |
monoclonal
|
Mouse
|
- |
- |
- |
- |
- |
|
|
Accurate |
monoclonal
|
Mouse
(semi-pure) |
RIA |
Human |
- |
|
- |
|
|
Accurate |
monoclonal
|
Mouse
(purified) |
ELISA, WB |
Human |
- |
β-Amyloid 1-40, secretory amyloid precurser; no cross with 17-42 |
- |
|
|
Accurate |
kit
|
Rabbit
|
IF |
Human |
- |
β-Amyloid 1-40 |
- |
|
|
Accurate |
polyclonal
|
Rabbit
|
RIA |
Human |
- |
β-Amyloid 1-40 |
- |
|
|
Accurate |
polyclonal
|
Rabbit
(purified) |
- |
Human |
- |
β-Amyloid 1-40 |
- |
|
|
Accurate |
polyclonal
|
Rabbit
(serum) |
IH |
Human |
- |
β-Amyloid 1-40 |
- |
|
|
Accurate |
polyclonal
IgG1κ |
Rabbit
|
DB, ELISA, IH, IP, WB |
Human |
1-40 |
amyloid plaque |
- |
|
|
Accurate |
monoclonal
|
Mouse
(purified) |
ELISA |
Human |
immunogen = β-Amyloid peptide 10-16 |
β-Amyloid |
- |
|
|
Accurate |
monoclonal
|
Mouse
(purified) |
ELISA |
Human |
immunogen = β-Amyloid peptide 9-10 |
β-Amyloid |
- |
|
|
Accurate |
monoclonal
|
Mouse
(purified) |
ELISA |
Human |
immunogen = β-Amyloid peptide 10-16 |
β-Amyloid |
- |
|
|
Accurate |
monoclonal
|
Mouse
(purified) |
ELISA |
Human |
immunogen = β-Amyloid peptide 10-16 |
β-Amyloid |
- |
|
|
Accurate |
monoclonal
|
Mouse
(purified) |
ELISA |
Human |
immunogen = β-Amyloid peptide 5-9 |
β-Amyloid |
- |
|
|
Accurate |
monoclonal
|
Mouse
(ready-to-use) |
IH |
Human |
- |
- |
- |
|
|
Accurate |
polyclonal
|
Rabbit
|
RIA |
- |
immunogen = amyloid β-protein 1-40 |
- |
- |
|
|
Accurate |
polyclonal
|
Rabbit
|
IH, WB |
- |
immunogen = amyloid β-protein 1-40 |
- |
- |
|
|
Accurate |
polyclonal
|
Rabbit
(serum) |
ID, WB |
Human |
immunogen = amyloid protein |
- |
- |
|
|
Accurate |
monoclonal
|
Mouse
(serum, biotinylated) |
- |
Human |
immunogen = amyloid protein |
- |
- |
|
|
Accurate |
monoclonal
|
Mouse
(purified) |
IH, WB |
Human, Mouse |
immunogen = amyloid β-protein (1-40) |
- |
- |
|
|
Accurate |
monoclonal
|
Mouse
(purified) |
- |
Human |
immunogen = amyloid β |
- |
- |
|
|
Anawa |
polyclonal
|
Rabbit
(Ig fraction, affinity purified) |
- |
Human |
immunogen = human amyloid beta from N-terminal |
- |
- |
|
|
Anawa |
polyclonal
|
Rabbit
(Ig fraction, affinity purified) |
- |
Human |
immunogen = human amyloid beta-(N3pE) |
- |
- |
|
|
Anawa |
monoclonal
IgG1 |
Mouse
(Ig fraction) |
IH |
Human |
immunogen = human amyloid beta-(N3pE) |
- |
- |
|
|
Anawa |
kit
|
Unknown Host
|
IF |
Human |
- |
Amyloid beta |
- |
|
|
Anawa |
polyclonal
|
Rabbit
(antiserum) |
RIA |
- |
immunogen = amyloid beta aa 1-28 |
Amyloid beta |
- |
|
|
Anawa |
polyclonal
|
Rabbit
(Ig fraction, affinity purified) |
- |
Human |
immunogen = human amyloid beta aa 1-40 |
Amyloid beta |
- |
|
|
Anawa |
polyclonal
|
Rabbit
(liquid, serum, glycerolated) |
RIA |
Human |
immunogen = human amyloid beta aa 1-40 |
Amyloid beta |
- |
|
|
Anawa |
polyclonal
|
Rabbit
(lyophilized, Ig fraction, PBS) |
IH, RID, WB |
Human |
immunogen = synthetic amyloid beta aa 1-40, coupled to human thyroglobulin |
Amyloid beta; stains senile plaques in AD brains |
- |
|
|
Anawa |
polyclonal
|
Rabbit
(Ig fraction, affinity purified) |
- |
- |
immunogen = human amyloid beta aa 1-42 |
Amyloid beta |
- |
|
|
Anawa |
polyclonal
IgG1 |
Rabbit
(Ig fraction) |
IH |
- |
immunogen = human amyloid beta aa 11-28 |
Amyloid beta |
- |
|
|
Anawa |
polyclonal
|
Rabbit
(Ig fraction, affinity purified) |
- |
- |
immunogen = human amyloid beta aa 1-43 |
Amyloid beta |
- |
|
|
Anawa |
polyclonal
|
Rabbit
(liquid, IgG fraction, KPBS, azide, sterile filtered) |
ELISA, WB |
Human, Mouse |
immunogen = human amyloid beta N-terminal (aa 1-14) seq : D A E F R H D S G Y E V H H, conj to KLH |
Amyloid beta |
- |
|
|
Biotrend |
monoclonal
IgG1, κ |
Mouse
(Ig fraction) |
ELISA |
Human |
immunogen = human amyloid beta-peptide aa 5-16 |
- |
- |
|
|
Biotrend |
monoclonal
IgG2a, κ |
Mouse
(Ig fraction) |
ELISA |
Human |
immunogen = human amyloid beta-peptide aa 5-16 |
- |
- |
|
|
Biotrend |
monoclonal
IgG1, κ |
Mouse
(Ig fraction) |
ELISA |
Human |
immunogen = human amyloid beta-peptide aa 5-16 |
- |
- |
|
|
Biotrend |
monoclonal
IgG2a, κ |
Mouse
(Ig fraction) |
ELISA |
Human |
immunogen = human amyloid beta-peptide aa 5-16 |
- |
- |
|
|
Biotrend |
polyclonal
|
Rabbit
(Ig fraction, affinity purified) |
- |
Human |
immunogen = human amyloid beta from N-terminal |
- |
- |
|
|
Biotrend |
polyclonal
|
Rabbit
(Ig fraction, affinity purified) |
- |
Human |
immunogen = human amyloid beta-(N3pE) |
- |
- |
|
|
Biotrend |
monoclonal
IgG1 |
Mouse
(Ig fraction) |
IH |
Human |
immunogen = human amyloid beta-(N3pE) |
- |
- |
|
|
Biotrend |
monoclonal
IgG1 |
Mouse
(diluted ascites) |
IH |
Human |
- |
Amyloid beta |
- |
|
|
Biotrend |
polyclonal
|
Rabbit
(Ig fraction, affinity purified) |
- |
Human |
immunogen = human amyloid beta aa 1-40 |
Amyloid beta |
- |
|
|
Biotrend |
polyclonal
|
Rabbit
(liquid, neat serum, glycerated) |
RIA |
Human |
immunogen = Aβ[1-40] coupled to hTg |
Aβ[1-40]; not TRH, Beta endorphin, LHRH, BNP (human), Amylin (human) or insulin (porcine). |
- |
|
|
Biotrend |
polyclonal
Ig |
Rabbit
(lyophilized, purified Ig fract) |
IH, RID, WB |
Human |
synthetic 1-40 β amyloid coupled to human Thyroglobulin |
stains senile plaques in brain sections of Alzheimer patients |
- |
|
|
Biotrend |
monoclonal
|
Mouse
(ascites) |
- |
- |
immunogen = human amyloid beta aa 1-40/42 |
Amyloid beta |
- |
|
|
Biotrend |
polyclonal
|
Rabbit
(Ig fraction, affinity purified) |
- |
Human |
immunogen = human amyloid beta aa 1-42 |
Amyloid beta |
- |
|
|
Pierce Thermo Scientific |
monoclonal
IgG2aκ |
Mouse
(frozen liquid, PBS) |
- |
Human |
immunogen = synthetic peptide corresponding to 28 a.a. sequence |
all forms of β-Amyloid |
- |
|
|
BD Pharmingen |
polyclonal
|
Rabbit
(affinity purified) |
DB, ELISA, IH, RIA |
Human |
synthetic peptide [1-43] |
Amyloid Beta [1-43]; not [1-40] or [1-42] |
- |
|
|
Araclon Biotech |
polyclonal
|
Rabbit
(affinity purified or serum) |
ELISA, IH, WB |
Dog, Dolphin, Chicken, Human, Mouse, Rat |
synthetic peptide for C-terminal of human β-Amyloid 1-40 |
Amyloid β 1-40. In IH it works diluted at 1:2000 and stains amyloid plaques in brain tissues and amyloid deposits in blood vessels. In WB it detects Amyloid β 1-40 (range of 1 ng) |
- |
|
|
Araclon Biotech |
polyclonal
|
Rabbit
(affinity purified or serum) |
ELISA, IH, WB |
Dog, Dolphin, Chicken, Human, Mouse, Rat |
synthetic peptide for C-terminal of human β-Amyloid 1-42 |
Amyloid β 1-42. In IH it works diluted at 1:2000 and stains amyloid plaques and cells in brain tissues and amyloid deposits in blood vessels. In WB it detects Amyloid β 1-42 (range of 1 ng) |
- |
|
|
Araclon Biotech |
polyclonal
|
Rabbit
(affinity purified) |
IH, WB |
Dog, Dolphin, Chicken, Human |
synthetic peptide, for N-terminal of human β-Amyloid |
In IH it works diluted at 1:2000 and stains amyloid plaques in brain tissues and amyloid deposits in blood vessels. In WB it detects both Amyloid β 1-40 and 1-42 |
- |
|
|
OYC |
polyclonal
|
Rabbit
(liquid, antiserum, azide) |
ELISA, WB |
Human |
immunogen = synthetic peptide of human β-Amyloid 1-40 |
The antibody reacts with βAP1-40, but not with either βAP17-42 or secretory amyloid protein precursor (sAPP) |
- |
|
|
Genetics Company, Inc. |
kit
|
Unknown Host
(Solid phase sandwich ELISA test, detection range of 25-500pg/ml) |
ELISA |
Human |
Monoclonal detection and capture antibodies |
Aβ 40 in a variety of samples, cell culture supernates, primary neurons, brain lysates; not Aβ 1-38, Aβ 1-39, Aβ 1-40; low cross reactivity with Aβ 1-43 (13%), Aβ 1-44 (10%) |
- |
|
|
AbD Serotec |
monoclonal
IgG1 |
Mouse
(liquid, supernatant, PBS, azide, affinity purified) |
IH, IP, WB |
Human |
immunogen = synthetic peptide consisting of residues 1 - 17 of the amyloid-β protein |
β-amyloid |
- |
|
|
AbD Serotec |
polyclonal
|
Rabbit
(liquid, serum, azide) |
ELISA, IH, WB |
Human |
immunogen = highly purified antigen |
β-amyloid 1-40 |
- |
|
|
AbD Serotec |
polyclonal
|
Rabbit
(liquid, serum, azide) |
ELISA, IH, WB |
Human |
immunogen = highly purified antigen |
β-amyloid 1-42 |
- |
|
|
AnaSpec |
polyclonal
|
Rabbit
(liquid PBS, azide, affinity purified) |
IP |
Human |
Immunogen = synthetic peptide corresp. to a portion of human β-amyloid 1-40 conj. KLH; GenBank NP_958817 |
β-Amyloid 1-40 |
- |
|
|
Autogen Bioclear |
monoclonal
IgG2a |
Mouse
(liquid, PBS, gelatin, azide, affinity purified) |
ELISA, IF, IH, IP, WB |
Human |
immunogen = synthetic peptide |
β-amyloid |
- |
|
|
Autogen Bioclear |
monoclonal
IgG2a, κ |
Mouse
(liquid, PBS, no preservative, protein A purified) |
ELISA, IH, WB |
Human |
immunogen = synthetic peptide of 28 aa corresp. to A4 sequence |
β-amyloid, all forms |
- |
|
|
Autogen Bioclear |
monoclonal
IgG2a |
Mouse
(liquid, PBS, gelatin, azide) |
IF, IP, WB |
Human, Mouse, Rat |
immunogen = aa 672-714 of amyloid A4 respresenting full length human β-amyloid |
β-amyloid and amyloid A4 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Goat
(liquid, PBS, gelatin, azide, affinity purified; blocking peptide [sc-5399P]) |
IF, IP, WB |
Human, Mouse, Rat |
immunogen = peptide mapping at the C-terminus of human β-amyloid |
β-amyloid (4kDa) and amyloid A4 |
- |
|
|
Autogen Bioclear |
polyclonal
|
Goat
(liquid or lyophilized, neat serum, azide) |
ELISA, IF, IH, WB |
Rabbit, Chicken, Sheep, Pig, Human, Guinea Pig, Mouse, Rat |
immunogen = synthetic 10-24 aa of human amyloid beta 1-40/42 conj. to KLH |
amyloid beta 1-40/42/43 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Rabbit
(liquid, neat serum, thimerosal or merthiolate, affinity purified) |
ELISA, IF, IH, WB |
Human, Mouse, Rat |
immunogen = C-terminal 8 aa peptide from human beta 1-40, conj. to KLH |
amyloid beta 1-40 and 1-42; weak cross-reactivity with 1-28 and 12-28; no cross reactivity with CGRP |
- |
|
|
Autogen Bioclear |
polyclonal
|
Rabbit
(liquid, PBS, no preservative, affinity purified) |
ELISA, RIA, WB |
- |
immunogen = C-terminus of human b-Amyloid 1-40 |
amyloid beta 1-40; no significant cross reactivity with beta-1-42/43 |
- |
|
|
Autogen Bioclear |
kit
|
Unknown Host
|
ELISA |
Human |
- |
amyloid beta (cell culture) |
- |
|
|
Autogen Bioclear |
kit
|
Unknown Host
|
ELISA |
Human |
- |
amyloid beta (cerebrospinal fluid) |
- |
|
|
Autogen Bioclear |
polyclonal
|
Rabbit
(liquid, PBS, no preservative, affinity purified) |
ELISA, RIA, WB |
- |
immunogen = C-terminus of human b-Amyloid 1-43 |
amyloid beta 1-43; no significant cross reactivity with beta-1-40/42 |
- |
|
|
Autogen Bioclear |
polyclonal
|
Rabbit
(liquid, serum, thimerosal or merthiolate) |
ELISA, IF, IH, WB |
Human, Mouse, Rat |
immunogen = C-terminal 8 aa peptide from human beta 1-40 conj. to KLH |
amyloid beta 1-40 and 1-42; weak cross-reactivity with 1-28 and 12-28; no cross-reactivity with CGRP |
- |
|
|
Autogen Bioclear |
polyclonal
|
Rabbit
(liquid, serum, thimerosal or merthiolate) |
ELISA, IF, IH, WB |
Human, Mouse, Rat |
immunogen = synthetic beta 1-40 conj. to BSA |
amyloid beta 1-40 and 1-42; weak cross-reactivity with 1-28 and 12-28; no cross- reactivity with CGRP |
- |
|
|
Autogen Bioclear |
monoclonal
IgG1 |
Mouse
(liquid or lyophilized, ascites, azide) |
ELISA, IF, IH, WB |
Human, Mouse, Rat |
immunogen = human beta 1-40 conj. to KLH; epitope located within 1-13 aa |
recognises N-terminus 1-13 aa of beta amyloid 1-40/42/43 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Rabbit
(liquid, serum, thimerosal or merthiolate, purified) |
ELISA, IF, IH, WB |
Human, Mouse |
immunogen = C-terminal 6 aa peptide from human beta 1-42 conj. to KLH |
amyloid beta 1-42; no cross-reactivity with 1-40 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Rabbit
(lyophilized, neat serum) |
ELISA, IF, IH, WB |
Human, Mouse, Rat |
immunogen = C-terminal 6 aa peptide from human beta 1-42 conj. to KLH |
amyloid beta 1-42; no cross-reactivity with 1-40 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Rabbit
(liquid, PBS, gelatin, azide) |
IF, IP, WB |
Human, Mouse, Rat |
immunogen = amino acids 672-714 of amyloid A4 representing full length human β-amyloid |
β-amyloid and amyloid A4 |
- |
|
|
Autogen Bioclear |
kit
|
Unknown Host
|
ELISA |
Human |
- |
amyloid beta-40 only (isoforms in plasma, brain tissue, cerebrospinal fluid and cell culture supernatants) |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Rabbit
(serum, thimerosal or merthiolate; available as affinity purified [BAM421-A]) |
ELISA, IF, IH |
Human, Mouse, Rat |
immunogen = synthetic C-terminal 8 aa peptide from human beta 1-42, conj. to KLH |
amyloid beta 1-42; no appreciable reactivity with b-1-40 |
- |
|
|
Autogen Bioclear |
polyclonal
IgG |
Goat
(liquid, PBS, gelatin, azide, affinity purified; blocking peptide [sc-5400P]) |
IF, IH, WB |
Human, Mouse, Rat |
immunogen = peptide mapping at the C-terminus of human β-amyloid |
β-amyloid (4kDa) and amyloid A4 |
- |
|
|
Autogen Bioclear |
monoclonal
IgG2a |
Mouse
(liquid, PBS, gelatin, azide) |
IF, IH, WB |
Human |
immunogen = synthetic peptide corresp. to aa 1-16 of human β-amyloid |
detects synthetic β-Amyloid [the N-termini of Aβ (40) and Aβ (42)]; no cross-reaction with recombinant β- amyloid (aa 601-744) |
- |
|
|
Autogen Bioclear |
monoclonal
IgG2a |
Mouse
(liquid, PBS, gelatin, azide) |
ELISA |
Human |
immunogen = synthetic peptide corresp. to aa 5-16 of human β-amyloid coupled to S3 and epinephrine |
β-Amyloid |
- |
|
|
Autogen Bioclear |
monoclonal
IgG1 |
Mouse
(liquid, PBS, gelatin, azide) |
IF, IH, IP, WB |
Human |
immunogen = aa 1-17 of human β-amyloid |
β-Amyloid |
- |
|
|
rPeptide, LLC |
monoclonal
IgG2bκ |
Mouse
(liquid, semipurified Ig, serum-free , DMEM, thimerosal) |
IH |
Human |
immunogen = AD brain amyloid |
recognizes senile plaques and all stages of amyloid deposits in AD brains |
- |