|
|
eBioscience |
monoclonal
IgG2b,κ |
Rat
(liquid, phosphate buffer, azide, PE-Cy5 conj.) |
FC |
Mouse |
- |
specific for CD11b and Mac-1α /αM β2 integrin |
- |
|
|
AbD Serotec |
monoclonal
IgG1 |
Mouse
(liquid, affinity purified IgG, azide) |
FC, IH |
Rat |
immunogen = Rat spleen cell homogenate |
reacts with rat spleen cell homogenate; recognises small ramified microglia in the central nervous system |
- |
|
|
ATCC |
monoclonal
IgM,κ |
Mouse
(frozen liquid, Modified Dulbecco's medium, heat-inactivated gamma globulin free horse serum) |
- |
Dog, Human, Rat |
immunogen = human acute monocytic leukemia cells (FAM M6) |
reacts with human CD11b, and blocks all known CD11b dependent activities in vitro |
- |
|
|
ATCC |
monoclonal
IgG2a,κ |
Mouse
(frozen liquid, Modified Dulbecco's medium, heat-inactivated gamma globulin free horse serum) |
- |
Primate (various), Human |
immunogen = human acute monocytic leukemia cells (FAM M6) |
reacts with human CD11b, and blocks a variety of CD11b dependent activities in vitro |
- |
|
|
ATCC |
monoclonal
IgG1 |
Mouse
(frozen liquid, ATCC complete growth medium) |
- |
Human |
immunogen = immunoprecipitates of human granulocyte lysates |
reacts with CD11b/MAC-1, and is specific for the alpha chain |
- |
|
|
ATCC |
monoclonal
IgG2b |
Mouse
(frozen liquid, ATCC-formulated Dulbecco's Modified Medium, fetal bovine serum) |
- |
Human |
immunogen = human peripheral blood mononuclear cells (monocytes) |
reacts with CD11b |
- |
|
|
R&D Systems |
monoclonal
IgG1 |
Mouse
(filtered, protein-G purified, PBS, trehalose, lyophilized) |
FC, IH |
Human |
immunogen = mouse B cells |
detects Integrin αM |
- |
|
|
R&D Systems |
monoclonal
IgG2B |
Mouse
(filtered, protein-G purified IgG fraction, PBS, trehalose, lyophilized) |
FC, IC |
Human |
immunogen = NS0-derived rhIntegrin αM extracellular domain |
detects Integrin αM |
- |
|
|
R&D Systems |
monoclonal
IgG2B |
Mouse
(liquid, ready to use, APC conj.) |
FC |
Human |
immunogen = NS0-derived rhIntegrin αM extracellular domain |
detects Integrin αM |
- |
|
|
R&D Systems |
monoclonal
IgG1 |
Mouse
(filtered, protein-G purified IgG fraction, PBS, trehalose, lyophilized) |
ELISA, WB |
Human |
immunogen = NS0-derived rhIntegrin αM extracellular domain |
detects Integrin αM |
- |
|
|
R&D Systems |
monoclonal
IgG1 |
Mouse
(filtered, protein-G purified, biotinylated, PBS, trehalose, lyophilized) |
FC, IH |
Human |
immunogen = mouse B cells |
detects Integrin αM |
- |
|
|
R&D Systems |
monoclonal
IgG2B |
Mouse
(liquid, ready to use, Phycoerythrin conj.) |
FC |
Human |
immunogen = NS0-derived rhIntegrin αM extracellular domain |
detects Integrin αM |
- |
|
|
Chemicon and Upstate are Millipore |
monoclonal
IgG2c |
Rat
(liquid, ascites) |
FC, IH, IS |
Mouse |
immunogen = mouse integrin VLA-5 (alpha5beta1) from mouse embryonal carcinoma P19 cells |
detects Integrin α5/β1 |
- |
|
|
Chemicon and Upstate are Millipore |
monoclonal
IgG3 |
Rat
(liquid, ascites, no preservatives) |
FC, IH, IP, IS, WB |
Mouse |
immunogen = mouse embryonal carcinoma P19 cells with myeloma P3X63Ag9.653 cells |
detects Integrin α5/β1 |
- |
|
|
Chemicon and Upstate are Millipore |
monoclonal
IgG2b,κ |
Rat
(liquid, protein-A purified) |
FC, IP |
Pig, Human |
- |
detects Integrin α5/β1 |
- |
|
|
Chemicon and Upstate are Millipore |
monoclonal
IgG2b,κ |
Rat
(liquid, ascites, no preservatives) |
FC, IP, IS |
Mouse |
- |
detects Integrin α5/β1 |
- |
|
|
Chemicon and Upstate are Millipore |
monoclonal
IgG1 |
Mouse
(liquid, ascites, unpurified, no preservatives) |
IH, IP, IS |
Human, Monkey |
immunogen = Jurkat cells |
recognizes Integrin α5/β1 |
- |
|
|
Chemicon and Upstate are Millipore |
monoclonal
IgG1 |
Mouse
(liquid, protein-A purified IgG, PBS, BSA, azide) |
ELISA, IC, IH, IP, RIA |
Human |
immunogen = human renal carcinoma cell line (KJ29) |
Recognizes an epitope related to the VLA-3 complex (alpha-3/beta-1 integrin) |
- |
|
|
R&D Systems |
monoclonal
IgG2B |
Rat
(filtered, protein-G purified IgG fraction, PBS, trehalose, lyophilized) |
FC, IH, IP |
Mouse |
immunogen = Con A-activated splenocytes |
recognizes Integrin αM |
- |
|
|
R&D Systems |
monoclonal
IgG2B |
Rat
(liquid, PBS, Carboxy fluorescein conj., azide) |
FC |
Mouse |
immunogen = Con A-activated splenocytes |
recognizes Integrin αM |
- |
|
|
R&D Systems |
monoclonal
IgG2B |
Rat
(filtered, protein-G purified IgG fraction, PBS, BSA, biotinylated, lyophilized) |
FC, IH, IP |
Mouse |
immunogen = Con A-activated splenocytes |
recognizes Integrin αM |
- |
|
|
R&D Systems |
monoclonal
IgG2B |
Rat
(liquid, PBS, Phycoerythrin conj., azide) |
FC |
Mouse |
immunogen = Con A-activated splenocytes |
recognizes Integrin αM |
- |
|
|
R&D Systems |
polyclonal
IgG |
Goat
(filtered, affinity purified, PBS, trehalose, lyophilized) |
ELISA, WB |
Human |
immunogen = NS0-derived rhIntegrin αM extracellular domain |
detects Integrin αM |
- |
|
|
Novus Biologicals |
polyclonal
|
Rabbit
(liquid, antisera, Tris-glycine, saline, azide, affinity purified.Also available as HRP, Biotin or HiLyte Fluor™ 488 conj.) |
IH, WB |
Human, Mouse |
immunogen = synthetic peptide made to an internal region (within residues 500-600) of the mouse CD11 (b/c) protein |
reacts with CD11; doublet is seen ~95 and 103 kDa in WB |
- |
|
|
AbD Serotec |
monoclonal
IgG2a |
Goat
(liquid, affinity purified, PBS, azideSee list of conjugates) |
FC, IH, IP |
Rat |
immunogen = rat peritoneal macrophages |
reacts with the rat equivalent of human CD11b, the receptor for the iC3b component of complement; CD11b is expressed on most macrophages |
- |
|
|
AbD Serotec |
monoclonal
IgG2b |
Rat
(liquid, supernatant, Tris saline, calf serum, azideSee list of other formats) |
FC, IH, IP |
Rabbit, Human, Mouse |
immunogen = T cell enriched splenocytes from B10 mice |
recognizes the murine CD11b cell surface antigen |
- |
|
|
AbD Serotec |
monoclonal
IgG2b and IgG1 |
Rat
(PBS, BSA, azide, lyophilized, dual color, ALEXA FLUOR® 488 / RPE) |
FC, IH |
Mouse |
immunogen = T cell enriched splenocytes from B10 mice |
recognizes murine CD115 and CD11b cell surface antigen |
- |
|
|
AnaSpec |
polyclonal
|
Rabbit
(liquid, affinity purified, PBS, BSA, azide) |
IF, IH, IP, WB |
Human, Hamster, Mouse, Rat |
immunogen = a synthetic peptide from the C-terminus of human integrin 5 subunit |
detects Integrin-β5 |
- |
|
|
BD Pharmingen |
monoclonal
IgG2b,κ |
Rat
(aqueous buffered solution, affinity purified, stabilizer, azide, Alexa Fluor® 700 conj.) |
FC |
Human, Mouse |
immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes |
reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported |
- |
|
|
BD Pharmingen |
monoclonal
IgG2b,κ |
Rat
(aqueous buffered solution, affinity purified, stabilizer, azide, Alexa Fluor® 647 conj.) |
FC |
Human, Mouse |
immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes |
reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported |
- |
|
|
BD Pharmingen |
monoclonal
IgG2b,κ |
Rat
(aqueous buffered solution, affinity purified, stabilizer, azide, Alexa Fluor® 488 conj.) |
FC |
Human, Mouse |
immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes |
reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported |
- |
|
|
BD Pharmingen |
monoclonal
IgG1,κ |
Mouse
(aqueous buffered solution, affinity purified, BSA, goat serum, azide) |
IH |
Human |
immunogen = Human monocytes |
detects CD11b; significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP. |
- |
|
|
BD Pharmingen |
monoclonal
IgG1,κ |
Mouse
(liquid, affinity purified, aqueous buffered solution, azide, Pacific Blue™ conj.Also available APC-Cy™7 conj, #557754PE-Cy™5 conj, #555389PE-Cy™7 conj, #557743) |
FC |
Human |
immunogen = Human monocytes |
reacts with CD11b; significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP. |
- |
|
|
BD Pharmingen |
monoclonal
IgG1,κ |
Mouse
(aqueous buffered solution, affinity purified, stabilizer, azide, Alexa Fluor® 488 conj.Also available Alexa Fluor® 700 conj, #557918) |
FC |
Human |
immunogen = Human monocytes |
reacts with CD11b; significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP |
- |
|
|
BD Pharmingen |
monoclonal
IgG1,κ |
Mouse
(liquid, affinity purified, aqueous buffered solution, BSA, azide, R-PE conj.Also available Biotin Conj, #555387) |
FC |
Human |
immunogen = Human monocytes |
reacts with CD11b; significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP. |
- |
|
|
BD Pharmingen |
monoclonal
IgG1,κ |
Mouse
(liquid, affinity purified, aqueous buffered solution, azide.Also available No azide/low endotoxin, #555385) |
FC, IH |
Human |
immunogen = Human monocytes |
reacts with CD11b; significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP. |
- |
|
|
BD Pharmingen |
monoclonal
IgG2b,κ |
Rat
(aqueous buffered solution, affinity purified, stabilizer, azide, APC-Cy7 conj.Also available PerCP-Cy5.5 conj, #550993PE-Cy™7 conj, #552850APC conj, #553312PE conj, #553311) |
FC |
Human, Mouse |
immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes |
reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported |
- |
|
|
BD Pharmingen |
monoclonal
IgG2b,κ |
Rat
(aqueous buffered solution, affinity purified, stabilizer, azide, Biotin conj.Also available FITC conj, #553310) |
FC |
Human, Mouse |
immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes |
reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported |
- |
|
|
BD Pharmingen |
monoclonal
IgG2b,κ |
Rat
(aqueous buffered solution, affinity purified, azideAlso available No azide/low endotoxin, #553307, for IP, blocking) |
FC |
Human, Mouse |
immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes |
reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported |
- |
|
|
BD Pharmingen |
monoclonal
IgG2b,κ |
Rat
(affinity purified, IHC diluent containing serum and azide) |
FC, IH |
Human, Mouse |
immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes |
detects CD11b; stains the macrophages, granulocytes, dendritic cells, and NK cells |
- |
|
|
AbD Serotec |
monoclonal
IgG2b |
Rat
(liquid, purified IgG, PBS, azideSee list of other formats) |
FC, IH, IP |
Human, Mouse |
immunogen = Thioglycollate elicted Peritoneal Macrophages (TPM) |
recognizes mouse complement type 3 receptor (CR3) and precipitates a heterodimer of 165 and 95kD |
- |
|
|
Chemicon and Upstate are Millipore |
monoclonal
IgG2b |
Rat
(liquid, purified, PBS, azideAlso available Phycoerythrin conjugated, CBL1313P) |
FC, IF, IH, IP |
Mouse |
immunogn = B10 mouse spleen cells enriched with T cells |
specific to CD11b; recognizes a differentiation antigen situated on mononuclear phagocytes and granulocytes; the expression of this antigen (Mac 1) increases during monocyte maturation |
- |
|
|
Chemicon and Upstate are Millipore |
monoclonal
IgG2a |
Mouse
(liquid, protein-A affinity purified, PBS, azide.Also available protein-G purified, PBS, no preservatives, CBL1512Z, or FITC conjugated, CBL1512F) |
FC, IH, IP |
Rat |
immunogn = rat peritoneal macrophages |
recognizes most macrophages (including resident peritoneal and activated macrophages), Kupffer cells, but only about 35% of alveolar macrophages; also labels dendritic cells extensively, granulocytes and cells with the morphology of microglia in brain |
- |
|
|
Chemicon and Upstate are Millipore |
monoclonal
IgG1 |
Mouse
(liquid, purified, PBS, BSA, azide.Also available Phycoerythrin conjugated, CBL145P) |
FC, IH, IP, IS |
Baboon, Human, Monkey |
immunogn = synovial cells and human monocytes |
reacts with the integrin heterodimer of 165 kDa which comprises the CD11b receptor |
- |
|
|
Chemicon and Upstate are Millipore |
monoclonal
IgG2b |
Rat
(liquid, protein-G purified, PBS, no preservatives) |
FC, IF, IH, IP, IS |
Human, Mouse |
immunogn = T cell enriched splenocytes from B10 mice |
recognizes the murine alphaM integrin chain; stains polymorphonuclear cells, monocytes and NK cells |
- |
|
|
Chemicon and Upstate are Millipore |
monoclonal
IgG1 |
Mouse
(liquid, ascites, protein-A affinity purified, PBS, azide.) |
IC, IH |
Rat |
immunogn = spleen cell homogenate with FCA |
recognizes a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes; recognizes small ramified (micro) glial cells in the central nervous system |
- |
|
|
Chemicon and Upstate are Millipore |
monoclonal
IgG2a |
Mouse
(liquid, purified, PBS, azide) |
FC, IC, IH, IP, IS |
Human |
immunogn = leukemic cells of CML |
specific to CD11b; reacts with the CR3-receptor of inactivated C3b component of complement (C3bi) |
- |