|
|
BioLegend |
monoclonal
IgG2b |
Mouse
(liquid, PBS, no preservatives or carrier proteins, HRP conj.) |
ELISA, IH, WB |
Human, Mouse |
epitope lies within amino acids 18-22 of the beta amyloid peptide (VFFAE) |
reactive to aa 17-24 Aβ and to APPs |
Available from BioLegend |
|
|
BioLegend |
polyclonal
|
Rabbit
(liquid, PBS, no carrier protein or preservative, affinity purified) |
ELISA, IH, WB |
- |
imunogen = using beta amyloid peptide (amino acids 1-16) conjugated to KLH |
reacts with all isoforms of beta amyloid |
Available from BioLegend |
|
|
BioLegend |
monoclonal
IgG1 |
Mouse
(liquid, protein-A purified, PBS, no preservative or carrier proteins, AlexaFluor® labeled) |
ELISA, IH |
Human |
the epitope lies within amino acids 4-9 of beta amyloid (FRHDSG) |
reactive to aa 1-17 Aβ reacts to the abnormally processed isoforms, as well as precursor forms |
Available from BioLegend |
|
|
BioLegend |
monoclonal
IgG1 |
Mouse
(liquid, no preservatives or carrier proteins, purified) |
ELISA, IH, WB |
Human |
epitope lies within amino acids 1-8 of the β-Amyloid protein |
reacts to N-terminal aa 1-8 of β-Amyloid peptide and β-amyloid form of APP |
Available from BioLegend |
|
|
BioLegend |
monoclonal
IgG1 |
Mouse
(liquid, PBS, no preservative or carrier protein, affinity G purified) |
ELISA, IB, IH, WB |
Human, Mouse |
- |
reactive to the C-terminus of beta amyloid and specific for the isoform ending at the 40th amino acid |
Available from BioLegend |
|
|
BioLegend |
monoclonal
IgG1 |
Mouse
(liquid, PBS, no preservative or carrier proteins, protein A purified, biotinylated) |
IH |
Human, Mouse |
- |
reactive to C-terminus of Amyloid β and specific for the isoform ending at the 40th amino acid |
- |
|
|
BioLegend |
monoclonal
IgG1 |
Mouse
(liquid, PBS, no preservatives or carrier proteins, purified, conj. HRP) |
IH |
Human |
- |
reactive to the C-terminus of beta amyloid and specific for the isoform ending at the 40th amino acid |
- |
|
|
BioLegend |
monoclonal
IgG1 |
Mouse
(liquid, PBS, no preservative or carrier proteins, protein G purified IgG) |
ELISA, IH, WB |
Human, Mouse |
- |
reactive to C-terminus of Amyloid β and specific for the isoform ending at the 42nd amino acid |
Available from BioLegend |
|
|
BioLegend |
monoclonal
IgG1 |
Mouse
(liquid, PBS, biotin labelled) |
ELISA, IH, WB |
Human, Mouse |
- |
reactive to C-terminus of Amyloid β and specific for the isoform ending at the 42nd amino acid |
Available from BioLegend |
|
|
BioLegend |
monoclonal
IgG1 |
Mouse
(liquid, PBS, no preservative or carrier proteins, HRP conj.) |
- |
Human, Mouse |
- |
reactive to C-terminus of Amyloid β and specific for the isoform ending at the 42nd aa |
Available from BioLegend |
|
|
BioLegend |
monoclonal
IgG1 |
Mouse
(liquid, PBS no preservative or carrier proteins, IgG frac., protein A purified) |
ELISA, IH, WB |
Human, Mouse |
- |
reactive to C-terminus of Amyloid β and specific for the isoform ending at the 43rd amino acid |
Available from BioLegend |
|
|
BioLegend |
monoclonal
IgG1 |
Mouse
(liquid, PBS, no preservative or carrier protein, biotin conj.) |
ELISA, IB, IH, IP, WB |
Human, Mouse |
epitope = lies within amino acids aa3-8 of beta amyloid (E F R H D S) |
reactive to the C-terminus of beta amyloid and specific for the isoform ending at the 43rd amino acid |
Available from BioLegend |
|
|
BioLegend |
monoclonal
IgG1 |
Mouse
(liquid, PBS, purified) |
ELISA, IH, IP, WB |
Rodent (various) |
- |
recognizes sequence of Aβ, β-CTF, sAPP-α, and full length APP; negligible cross reactivity with human isoforms of APP and beta amyloid. |
Available from BioLegend |
|
|
BioLegend |
polyclonal
|
Rabbit
(liquid, PBS, no carrier protein or preservative, affinity purified) |
ELISA, IH, WB |
Rodent (various) |
imunogen = rodent amyloid-β peptide conj. to KLH |
recognizes beta amyloid, all isoforms |
Available from BioLegend |
|
|
BioLegend |
polyclonal
|
Rabbit
(liquid, PBS, glycerol, no carrier protein or preservative, boitin labeled) |
ELISA, IH, WB |
Rodent (various) |
- |
all isoforms of rhodent Aβ |
Available from BioLegend |
|
|
BioLegend |
monoclonal
IgG1 |
Mouse
(liquid, PBS; no preservatives or carrier proteins) |
ELISA, IH, WB |
- |
epitope lies within amino acids 1-10 of beta amyloid |
amyloid β |
Available from BioLegend |
|
|
BioLegend |
monoclonal
IgG1 |
Rabbit
(liquid, PBS, no carrier protein or preservative, affinity purified) |
ELISA, IB, WB |
Human, Rodent (various) |
imunogen = beta amyloid peptide (aa1-16) conj. to KLH |
reactive to the C-terminus of beta amyloid and specific for the isoform that ends at the 40th amino acid |
Available from BioLegend |
|
|
BioLegend |
polyclonal
|
Rabbit
(liquid, PBS, IgG fraction, no preservative or carrier protein) |
IH |
Rodent (various) |
immunogen = rodent amyloid-β peptide |
rodent Amyloid-β ,all isoforms |
Available from BioLegend |
|
|
None |
monoclonal
IgG1 |
Mouse
(liquid, PBS, no preservatives or carrier proteins, purified, HRP conj.) |
ELISA, IH, WB |
Human |
epitope = lies within aa 3-8 of the β-amyloid peptide (EFRHDS) |
reactive to aa 1-16 of β-Amyloid (precursor forms as well as abnormally processed isoforms |
Discontinued |
|
|
None |
monoclonal
IgG1 |
Mouse
(liquid, purified F(ab')2 frag of clone 6E10 monoclonal ab, PBS, no preservatives or carrier proteins) |
ELISA, IH, WB |
Human |
epitope = lies within aa 3-8 of β-amyloid peptide (EFRHDS) |
reactive to aa 1-16 of β-amyloid peptide (precursor forms and abnormally processed isoforms) |
Discontinued |
|
|
None |
monoclonal
IgG1 |
Mouse
(liquid, PBS; no preservatives or carrier proteins) |
ELISA, IH, IP, WB |
Human |
epitope lies within amino acids 3-8 of the beta Amyloid peptide (E F R H D S) |
reactive to amino acid residue 1-16 of beta amyloid.; reacts to the abnormally processed isoforms, as well as precursor forms |
Discontinued |
|
|
None |
monoclonal
|
Rabbit
(liquid, PBS, no carrier protein or preservative, purified) |
ELISA |
- |
- |
reactive to the C-terminus of beta amyloid and specific for the isoform that ends at the 42nd amino acid. |
Discontinued |
|
|
None |
polyclonal
IgG1 |
Rabbit
(liquid, PBS, glycerol, no preservative or carrier protein, affinity G purified, conj. biotin) |
IB, IH, WB |
Human, Mouse |
immunogen = peptide conj. to KLH. |
specific for the C-terminus of Aβ 42; reacts extremely well with the 42 isoform; no cross-reaction with Aβ 40 or APP |
Discontinued |
|
|
None |
polyclonal
IgG1 |
Rabbit
(liquid, PBS, no preservative or carrier protein, affinity G purified) |
IB, IH, WB |
Human, Mouse |
immunogen = peptide conj. to KLH. |
specific for the C-terminus of Aβ 42; reacts extremely well with the 42 isoform; no cross-reaction with Aβ 40 or APP |
Discontinued |
|
|
None |
polyclonal
IgG1 |
Rabbit
(liquid, PBS, glycerol, no preservative or carrier protein, conj. biotin) |
IH |
Human, Mouse |
immunogen = peptide conj. to KLH. |
specific for the C-terminus of Aβ 42; reacts extremely well with the 42 isoform; no cross-reaction with Aβ 40 or APP |
Discontinued |
|
|
None |
polyclonal
IgG |
Rabbit
(purified, IgG fraction, PBS, no preservatives or carrier proteins) |
IH |
Human, Mouse |
immunogen = amyloid β 1-42 peptide, conj. to KLH |
specific for the C-terminus of Aβ 1-42; no cross reaction with Aβ 1-40 or APP |
Discontinued |
|
|
None |
polyclonal
|
Rabbit
(liquid, PBS, glycerol, no preservative or carrier proteins, affinity purified, bintinylated) |
ELISA, IH, WB |
Human, Mouse |
immunogen = amyloid-β conj. to KLH |
specific for C-terminus of Aβ40 isoform; no cross-reaction with Aβ42 or APP |
Discontinued |
|
|
None |
polyclonal
|
Rabbit
(liquid, PBS, glycerol, no preservative or carrier proteins, IgG frac., biotinylated) |
IH |
Human |
immunogen = amyloid-β peptide conj. to KLH |
specific for C-terminus of Aβ 40 isoforms; no cross-reaction with Aβ 42 or APP |
Discontinued |
|
|
None |
polyclonal
|
Rabbit
(liquid, PBS, no preservative or carrier proteins, affinity purified) |
ELISA, IH, WB |
Human |
immunogen = amyloid-β conj. to KLH |
specific for C-terminus of Aβ 40 isoform; no cross-reaction with Aβ42 or APP |
Discontinued |
|
|
None |
monoclonal
IgG1 |
Mouse
(liquid, purified, no preservative or carrier proteins) |
ELISA, IH, WB |
Human |
epitope lies within amino acids 1-8 of the β-Amyloid peptide |
reacts to N-terminal aa 1-8 of β-amyloid peptide (precursor forms and abnormally processed isoforms) and β-amyloid form of APP |
Discontinued |
|
|
None |
kit
|
Unknown Host
(Chemiluminescent sandwich ELISA Kit: Capture Antibody Coated Plate; HRP Detection Antibody, chemiluminescent substrate) |
ELISA |
Human |
- |
specific for the 1-42 isoform of beta amyloid; has negligible cross reactivity with the 1-40 isoform of beta amyloid |
Discontinued |
|
|
None |
kit
|
Unknown Host
(Chemiluminescent sandwich ELISA Kit: Capture Antibody Coated Plate; HRP Detection Antibody, chemiluminescent substrate) |
ELISA |
Human, Rodent (various) |
- |
specific for the x-42 isoform of beta amyloid; has negligible cross reactivity with the x-40 isoform of beta amyloid |
Discontinued |
|
|
None |
kit
|
Unknown Host
(Chemiluminescent sandwich ELISA Kit: Capture Antibody Coated Plate; HRP Detection Antibody, chemiluminescent substrate) |
ELISA |
Human |
- |
reactive to Aβ; specific for the 1-40 isoform of beta amyloid; has negligible cross reactivity with the 1-42 isoform of beta amyloid |
Discontinued |
|
|
None |
kit
|
Unknown Host
(Chemiluminescent sandwich ELISA Kit: Capture Antibody Coated Plate; HRP Detection Antibody, chemiluminescent substrate) |
ELISA |
Human, Rodent (various) |
- |
reactive to the x-40 isoform of beta amyloid; has negligible cross reactivity with the x-42 isoform of beta amyloid |
Discontinued |
|
|
None |
kit
|
Unknown Host
(Sandwich ELISA Kit: Coated Capture Antibody; Primary Antibody; Secondary Antibody-HRP) |
ELISA |
- |
- |
specific for Aβ 1-42 |
Discontinued |
|
|
None |
kit
|
Unknown Host
(sandwich ELISA kit: capture, primary and secondary antibody-HRP) |
ELISA |
- |
- |
reactive to Aβ 1-40 |
Discontinued |
|
|
BioLegend |
monoclonal
IgM |
Mouse
(ascites, concentrate) |
ELISA, IC, IH, WB |
Mammal (various) |
non phos- phorylated epitope in neurofilament H |
neuronal cell bodies, dendrites and a some thick axonsin the central and peripheral nervous systems |
Available from BioLegend |
|
|
BioLegend |
monoclonal
IgG1 |
Mouse
(liquid, ascites, azide) |
ELISA, IC, IH, WB |
Mammal (various) |
non phosphory- lated epitope accessible in neurofilamentH |
wide distribution of neuronal cell bodies, dendritesand some thick axons in the central and peripheral nervous systems |
Available from BioLegend |
|
|
BioLegend |
monoclonal
IgM |
Mouse
(liquid, ascites, concentrate) |
ELISA, IC, IH, WB |
Mammal (various) |
non phos- phorylated epitope accessible in neurofilament H |
some neuronal cell bodies, dendrites and very few thickaxons in the central and peripheral nervous systems; some neuronal cellbodies are intensely stained but few neuronal cell processes react |
Available from BioLegend |
|
|
None |
monoclonal
IgG1 |
Mouse
(ascites, concentrate) |
IC, IH, WB |
Mammal (various) |
phosphorylated epitope in neurofilament H |
thick and thin axons and faintly stains some cell bodies;unlike the other antibodies to phosphorylated neurofilament epitopes, doesnot react with aluminum tangles |
Discontinued |
|
|
None |
monoclonal
IgG1 |
Mouse
(ascites, concentrate) |
IC, IH, WB |
Mammal (various), Chicken, Frog |
band extending from the phosphorylated neurofilamentposition at 200kD, pI 5.1, toward the non phosphorylated position at 170kD,pI 6.2 |
neurofilaments of high and low degrees of phosphorylationfrequently detects early changes in neuronal cell body staining |
Discontinued |
|
|
None |
monoclonal
IgG1 |
Mouse
(ascites, concentrate) |
IC, IH, WB |
Mammal (various), Chicken |
phosphorylated epitope in extensively phosphorylatedneurofilament H |
axonal antibody, also detecting intraneuronal Alzheimertangles; nerve cell bodies are generally unreactive |
Discontinued |
|
|
None |
monoclonal
IgM |
Mouse
(ascites, concentrate) |
IC, IH, WB |
Mammal (various) |
non phos- phorylated epitope accessible in both phosphorylatedand non phosphorylated neurofilament H and, to a lesser extent, in neurofilamentM |
neuronal cell bodies, dendrites and some thick axonsin the central and peripheral nervous systems; reaction with isolated neurofilamentsis not intensified by dephos- phorylation |
Discontinued |
|
|
None |
monoclonal
IgG1 |
Mouse
(liqiud, ascites, concentrate) |
IC, IH, WB |
Mammal (various) |
non phos- phorylated epitope neurofilament H |
neuronal cell bodies, dendrites and some thick axonsin the central and peripheral nervous systems, but not thin axons;reflects extent of aberrant phosphorylation of neurofilaments in Alzheimer'sdisease. SMI 32 visualizes two bands (200 and 180 kDa) which merge into a single NFH line on two-dimensional blots |
Discontinued |
|
|
None |
monoclonal
IgG1 |
Mouse
(liquid, ascites, concentrate) |
ELISA, IC, IH, WB |
Mammal (various), Chicken, Frog |
phosphorylated epitope in extensively phosphorylated neurofilament H |
phosphorylated neurofilament H and, to a lesser extent, neurofilament M is detected in most mammalian species, in thick and thin axons but not cell bodies |
Discontinued |
|
|
None |
monoclonal
IgG1 cocktail |
Mouse
(liquid, ascites, concentrate) |
ELISA, IC, IH, WB |
Mammal (various) |
- |
visualizes axons in an area-specific maturation patternin human fetal brain; visualizes aberrantly sprouting axons in neuriticplaques derived from cortico-cortical fibers in A.D. and identifies loss of synaptic circuitry |
Discontinued |
|
|
None |
monoclonal
IgG1 & IgM |
Mouse
(ascites, azide, concentrate) |
ELISA, IC, IH, WB |
Mammal (various) |
- |
Neurons with non phosphorylated neurofilaments; providesan early marker of neuronal migration and differentiation in human fetal development |
Discontinued |
|
|
None |
monoclonal
IgG1 |
Mouse
(liquid, ascites, concentrate) |
ELISA, IC, IH, WB |
Mammal (various) |
phosphorylated epitope in extensively phosphorylated neurofilament H |
phosphorylated neurofilament H and, to a lesser extent,neurofilament M, in axons but not dendrites. In A.D., extraneuronal (ghost)neurofibrillary tangles in frozen sections |
Discontinued |
|
|
BioLegend |
monoclonal
IgG2A |
Mouse
(liquid, purified, PBS, biotin conj.) |
ELISA, IH, IP, WB |
Cat, Human, Hamster |
epitope lies within amino acids 109-112 of prion protein |
3F4 is reactive to amino acid residues 109-112 of prion protein (PrP) from humans, hamsters, and felines. It recognizes both protease sensitive and protease resistant forms of PrP (after denaturing) |
Available from BioLegend |
|
|
BioLegend |
monoclonal
IgG2A |
Mouse
(liquid, purified, PBS,) |
ELISA, IH, IP, WB |
Cat, Human, Hamster |
epitope lies within amino acids 109-112 of prion protein |
3F4 is reactive to amino acid residues 109-112 of prion protein (PrP) from humans, hamsters, and felines. It recognizes both protease sensitive and protease resistant forms of PrP (after denaturing) |
Available through BioLegend |
|
|
BioLegend |
monoclonal
IgG2A |
Mouse
(liquid, ascites) |
ELISA, IH, IP, WB |
Cat, Human, Hamster |
epitope lies within amino acids 109-112 of prion protein |
3F4 is reactive to amino acid residues 109-112 of prion protein (PrP) from humans, hamsters, and felines. It recognizes both protease sensitive and protease resistant forms of PrP (after denaturing) |
Available from BioLegend |
|
|
BioLegend |
monoclonal
IgG1 |
Mouse
(supernatant, purified, PBS, no preservatives or carrier proteins) |
ELISA, IH, WB |
Bovine, Sheep, Mouse |
Immunogin within recombinant mouse PrP protein, aa 23-237 |
7D9 reacts exceptionally well with bovine, sheep, and mouse PrP. It is 10 fold less reactive to feline, hamster, and human PrP. 7D9 recognizes both protease sensitive and protease resistant forms of PrP |
Available from BioLegend |
|
|
BioLegend |
monoclonal
IgG2A,κ |
Mouse
(liquid, affinity purified, PBS, no preservatives or carrier proteins) |
ELISA, IB, IH |
Deer, Elk, Bovine, Mule, Sheep, Human, Hamster, Mouse |
The epitope falls within amino acids 93-109 of PrP |
6D11 reacts with both the PrPc and PrPsc forms |
Available from BioLegend |
|
|
None |
monoclonal
IgG1 |
Mouse
(supernatant, purified, PBS, no preservatives or carrier proteins) |
ELISA, IF, IH, WB |
Cat, Sheep, Rabbit |
The epitope site appears to be non-linear (discontinuous). |
This antibody recognizes both the cellular (protease sensitive) and infectious (protease resistant) isoforms of PrP |
Discontinued |