The Antibodies database was archived in December 2022 and is no longer being updated. The Antibodies database is being supplanted by the AlzAntibodies database, which aims to provide detailed descriptions of selected antibodies.

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Antibodies

29333 Results

Name Source Clonality &
Isotype
Host &
Formulation
Method Reactivity Immunogen/
Epitope
Specificity Availability
APP, APLP, AICD From labs (5)
anti-APP C7(Dr. Dennis Selkoe,Harvard Univ. Medical School, Boston, MA)Reference: Puglielli, 2001,by Yu, 2001 polyclonal
Rabbit
- - last 20 residues of APP   -
anti-APP C9(Dr. Dennis Selkoe,Harvard Univ. Medical School, Boston, MA)References:Muresan, 2009Sato, 2007 polyclonal
Rabbit
- - synthetic peptide corresp. to APP732-751, (APP751 numbering)   -
anti-APP α-1(Dr. Dennis Selkoe,Harvard Univ. Medical School, Boston, MA polyclonal
Rabbit
- Human synthetic peptide of residues 649-664 APP -
R1736(Dr. Dennis Selkoe,Harvard Univ. Medical School, Boston, MA)Reference: Maier, 2008, polyclonal
Rabbit
(antiserum)
- Rodent (various), Human immunogen = synthetic peptide of amino acids 595–611 of APP APP epitope corresponds to positions -2 to +15 of human Abeta, and it presents 90%(15 out of 17 amino acids) of sequence homology with the hamster sequence which is identical to other rodents such as mouse -
anti-APP C8(Dr. Dennis Selkoe,Harvard Univ. Medical School, Boston, MA)References: Davis, 2010Senechal, 2008Wang, 2007 polyclonal
Rabbit
- Mammal (various), Human residues 676-695, comprising the 20 C-terminal amino acids of human βAPP cytoplasmic domain.Paper, Selkoe et al. recognizes full length APP and all CTFs -
APP, APLP, AICD From manufacturers (1)
Synaptic Systems
Cat# 127 002
polyclonal
Rabbit
(antiserum, lyophilized. )
- Human, Mouse, Rat, Chicken, Frog Synthetic peptide GYENPTYKFFEQMQN corresponding to the C-terminus of APP coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue. Specific for APP. Confirmed available March 2014
Amyloid-β From labs (2)
- monoclonal
IgG1
Rat
(supernatant)
- Human This antibody was raised against the native human APP ectodomain (isoform 695, which lacks the KPI domain). The epitope is believed to lie between amino acids 40 and 64. Specific to human APP. Does not cross-react with mouse, rat, dog, or guinea pig. Contact Stefan Lichtenthaler
- monoclonal
IgG1
Rat
(supernatant)
- Human This antibody was raised against the native human APP ectodomain (isoform 695, which lacks the KPI domain). The epitope is believed to lie between amino acids 40 and 64. Specific to human APP. Does not cross-react with mouse, rat, dog, or guinea pig. Contact Stefan Lichtenthaler
Amyloid-β From manufacturers (9)
Synaptic Systems monoclonal
IgG2b
Mouse
(affinity purified, buffered, azide, lyophilized)
- Human, Mouse, Rat Balb/c mice were immunized with a KLH-coupled pyroglutamate-Abeta-peptide with the peptide pE F R H D-C.After preparation of the lymph nodes, cells were fused with the myeloma cell line P3-963-Ag8 reactive to N-terminal truncated Abeta 3-X starting with pyroglutamate (pGlu, pE). Does not cross-react with N-terminal truncated Abeta 11-X starting with pGlu. -
Synaptic Systems monoclonal
IgG1
Mouse
(affinity purified, buffered, azide, lyophilized)
- Human, Mouse, Rat Balb/c mice were immunized with a KLH-coupled pyroglutamate-Abeta-peptide with the peptide pEFRHD-C.After preparation of the lymph nodes, cells were fused with the myeloma cell line P3-963-Ag8 reactive to N-terminal truncated Abeta 3-X starting with pyroglutamate (pGlu, pE). Does not cross-react with N-terminal truncated Abeta 11-X starting with pGlu. -
IBL
Cat# 10326
monoclonal
IgG1
Mouse
(affinity purified, lyophilized product from 1% BSA in PBS containing 0.05% NaN3; biotin-tagged)
- Human immunogen = synthetic peptide for human Amyloid β (1-16) (DAEFRHDS GYEVHHQK) Amyloid β and β-CTF N-terminal specific; reacts with both soluble and fibrillar Aβ to a similar degree; no reaction with holo-APP -
Biosensis
Cat# M-1586-100
monoclonal
IgG2b
Mouse
(Lyophilized; Protein A purified; 0.02 M potassium phosphate, 0.15 M sodium chloride, 0.01% sodium azide; pH 7.2)
- Human, Rat Epitope maps to residues 1-4 of human Aβ42 and Aβ40 (DAEF) Reacts with the N-terminal end of Aβ (amino acids 1-4). Appears to detect monomeric, oligomeric, and fibrillar forms of Aβ. Greater sensitivity for Aβ42 than Aβ40. Does not cross react with holo-APP or APP-CTFs. Confirmed available March 2015.
Abcam
Cat# ab126649
monoclonal
IgG2b
Mouse
(Protein G purified. PBS, 0.02% Sodium azide, pH: 7.40.)
- Human Epitope maps to residues 1-4 of human Aβ42 and Aβ40 (DAEF) Reacts with the N-terminal end of Aβ (amino acids 1-4). Appears to detect monomeric, oligomeric, and fibrillar forms of Aβ. Greater sensitivity for Aβ42 than Aβ40. Does not cross react with holo-APP or APP-CTFs. Confirmed available March 2015.
Cayman Chemical
Cat# 11610
monoclonal
IgG2b
Mouse
(Purified IgG in PBS, pH 7.2, containing 50% glycerol, and 0.02% sodium azide)
- Human Epitope maps to residues 1-4 of human Aβ42 and Aβ40 (DAEF) Reacts with the N-terminal end of Aβ (amino acids 1-4). Appears to detect monomeric, oligomeric, and fibrillar forms of Aβ. Greater sensitivity for Aβ42 than Aβ40. Does not cross react with holo-APP or APP-CTFs. Confirmed available March 2015.
Kerafast
Cat# EB2001
monoclonal
IgG2b
Mouse
(Protein G purified; hepes buffered saline, pH 7.4, 50% glycerol)
- Human, Mouse, Rat Epitope maps to residues 1-4 of human Aβ42 and Aβ40 (DAEF) Reacts with the N-terminal end of Aβ (amino acids 1-4). Appears to detect monomeric, oligomeric, and fibrillar forms of Aβ. Greater sensitivity for Aβ42 than Aβ40. Does not cross react with holo-APP or APP-CTFs. Confirmed available March 2015.
Millipore
Cat# MABN254
monoclonal
IgG2aλ
Mouse
(Protein G purified; buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. )
- Human Epitope maps to residues 1-4 of human Aβ42 and Aβ40 (DAEF) Reacts with the N-terminal end of Aβ (amino acids 1-4). Appears to detect monomeric, oligomeric, and fibrillar forms of Aβ. Greater sensitivity for Aβ42 than Aβ40. Does not cross react with holo-APP or APP-CTFs. Confirmed available March 2015.
Novus Biologicals
Cat# NBP-2-13075
monoclonal
IgG2b
Mouse
(Protein G purified; Tris-glycine buffer with 150mM NaCl and 0.05% Sodium Azide; pH 7.5 )
- Human, Mouse, Rat Epitope maps to residues 1-4 of human Aβ42 and Aβ40 (DAEF) Reacts with the N-terminal end of Aβ (amino acids 1-4). Appears to detect monomeric, oligomeric, and fibrillar forms of Aβ. Greater sensitivity for Aβ42 than Aβ40. Does not cross react with holo-APP or APP-CTFs. Confirmed available March 2015.
Iron Related From manufacturers (1)
LifeSpan Biosciences, Inc. polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide, glycerol)
- Human immunogen = synthetic peptide corresponding to N-terminal residues of human MTP1 (Metal transporter protein 1), conj. to KLH detects ferroportin -
Mitochondrial Proteins, Microglial Markers From manufacturers (1)
Abcam
Cat# ab109497
monoclonal
IgG
Rabbit
(Tissue culture supernatant. PBS 49 percent, sodium azide 0.01 percent, glycerol 50 percent, BSA 0.05 percent.)
- Human, Mouse A synthetic peptide corresponding to residues at the C-terminus of human peripheral benzodiazepine receptor (PBR)/translocator protein (TSPO). This antibody recognizes PBR, also known as TSPO, a mitochondrial transporter that is upregulated in activated microglia. Confirmed available December 2014.
Synucleins From labs (2)
α-Synuclein SNL-1(Virginia Lee, University of Pennsylvania, CNDR, Philadelphia, PA)used in paper by Giasson, 1999 polyclonal
Rabbit
- - immunogen = synthetic peptides corresponding to amino acids 104-119 in α-syn   -
α-Synuclein SNL-4(Virginia Lee, University of Pennsylvania, CNDR, Philadelphia, PA)used in paper by Giasson, 1999 polyclonal
Rabbit
- - immunogen = a synthetic peptide corresponding to residues 2-12 of α-synuclein   -
TAR DNA-binding protein /TDP-43 From manufacturers (1)
Millipore
Cat# MABN14
monoclonal
IgG2ak
Rat
(Purified in buffer containing 0.1 M Tris glycine with 0.05% sodium azide)
- Human Ovalbumin-conjugated linear peptide corresponding to human TDP-43 phosphorylated at serine 409 and 410. This antibody recognizes human TDP-43 phosphorylated at serine 409 and 410. Confirmed Oct 2014
Tau From labs (4)
Formerly available through Dr. Peter Davies. For updated information, see AlzAntibodies page linked in Note below. monoclonal
IgG1
Mouse
- Human, Mouse conformation dependent antibody (epitope within aa 312-322) reactivity depends on both the N terminus (amino acids 7–9), and an amino acid sequence of tau (amino acids 313–322) in the third microtubule binding domain. Recognizes neurofibrillary tangles but does not react with FAC1 -
Formerly available through Dr. Peter Davies. For updated information, see AlzAntibodies page linked in Note below. monoclonal
IgM
Mouse
- - Raised against human basal forebrain homogenate. Epitope subsequently determined to include amino acids 2-10 and 312-342 of tau. Recognizes a misfolded conformation of tau. 68 kDa Tau. Stains neuronal components of AD brain specimens but not normal brain specimens. -
Formerly available through Dr. Peter Davies. For updated information, see AlzAntibodies page linked in Note below. monoclonal
IgG1
Mouse
- Human Immunogen: paired helical filaments of tau. Epitope: around serine-396 and serine-404 phosphorylated sites. - -
Formerly available through Dr. Peter Davies. For updated information, see AlzAntibodies page linked in Note below. monoclonal
IgG2b
Mouse
- Human epitope around phospho-serine 202 Detects tau phosphorylated at serine-202. -
Tau From manufacturers (6)
Innogenetics monoclonal
Mouse
- Bovine, Human immunogen = purified human tau; (epitope within aa 159-163) phosphorylated and non phosphorylated tau -
Innogenetics monoclonal
IgG1κ
Mouse
(liquid, sterile filtered, PBS, no preservative, affinity purified)
- Human immunogen = human tau40, aa. around phospho. Thr 181 specific for tau phospho at Thr 181; as PHF-tau, tangles and neurofilaments; weak cross with normal tau; -
Innogenetics kit
Mouse
(solid-phase enzymeimmunoassay, uses monoclonal AT120 for capture, HT7 and BT2 for incubation. Streptavidin detection of the antibodies.)
- Human - tau in cerebrospinal fluid -
Synaptic Systems
Cat# 314011
monoclonal
IgG2a

(Purified IgG, lyophilized. Azide was added before lyophilization. Unconjugated.)
- Human, Mouse, Rat Recombinant mouse tau (amino acids 3 - 214) The antibody binds phosphorylated and non-phosphorylated tau proteins. Confirmed available March 2014
Synaptic Systems
Cat# 314 002
polyclonal
Rabbit
(antiserum, lyophilized. )
- Human, Mouse, Rat Recombinant mouse tau (amino acids 3 - 214). The antibody binds phosphorylated and non-phosphorylated tau proteins. Confirmed available March 2014
Pierce Thermo Scientific
Cat#  MN-1020
monoclonal
IgG1κ
Mouse
(Protein A affinity purified, PBS, no preservative)
- Baboon, Human, Rabbit, Hamster, Avian (various), Drosophila immunogen = partially purified human paired helical filament tau. Recognizes tau protein phosphorylated at both serine 202 (Ser202) and threonine 205 (Thr205). Does not cross-react with unphosphorylated forms of tau.   Confirmed available April 2015.
γ-secretase/ Presenilins From labs (1)
4627Dr. Dennis Selkoe,Harvard Univ. Medical School, Boston, MAReference: Sato, 2007 polyclonal
Rabbit
- Human, Hamster, Mouse immunogen = synthetic peptide corresp. to the C-terminal 10 amino acids of PS1 (aa 457-467) Paper extreme C-terminal PS1, and PS1 CTF -