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Antibodies

29333 Results

Name Source Clonality &
Isotype
Host &
Formulation
Method Reactivity Immunogen/
Epitope
Specificity Availability
APP, APLP, AICD From labs (1)
(Stefan Lichtenthaler, Adolf Butenandt Institute, Ludwig Maximilians University, München, Germany)Paper, Ulrich et al.Reference: Kuhn, 2010 monoclonal
IgG2a
Mouse
IP, WB Human immunogen = the peptide ISEVKM derived from the amino acids directly preceding the APPβ-secretase cleavage site detects APPsβ at the β cleavage site -
APP, APLP, AICD From manufacturers (3)
BioLegend monoclonal
IgG2b
Mouse
(purified PBS thimerosal no BSA)
ELISA, IH, IP, WB Human, Mouse amino acid residue 17-24 of beta Amyloid peptide reactive to aa 17-24 Aβ and to APP Available from BioLegend
None kit
IgG1
Rabbit
ELISA Human, Mouse, Rat immunogen = synthetic peptide corresp. to aa 573-596 of APP (amyloid precursor protein) specific for the β isoform of sAPP (soluble amyloid precursor protein). It has negligible cross reactivity with β amyloid 40, 42, or sAPPα Discontinued
BioLegend polyclonal
Rabbit
(affinity purified, PBS, no preservatives or carrier proteins)
ELISA - - reactive to C-terminal fragment of APP (APPc) Available from BioLegend
Amyloid-β From labs (1)
A11(paper comparing A11 and OC antibodies;source paper for A11; Charles G Glabe, University of California, Irvine)References:Lefterov, 2010 polyclonal
Rabbit
(serum)
DB, ELISA, IH, WB Human immunogen = soluble Amyloid oligomers generic epitope common to prefibrillar oligomers and not fibrils, monomers or natively folded precursor proteins. Stains small focal or punctuate deposits in AD tissue does not stain diffuse plaques or other plaque types. Stains Aβ and polyQ prefibrillar oligomers. -
Amyloid-β From manufacturers (2)
BioLegend monoclonal
IgG1
Mouse
(biotinylated IgG, PBS, no preservatives or carrier proteins)
ELISA, IH, IP, WB Human the epitope lies within amino acids 3-8 of beta amyloid (EFRHDS) reactive to aa 1-16 Amyloid β; reacts to the abnormally processed isoforms, as well as precursor forms Available from BioLegend
None polyclonal
IgG
Rabbit
(Purified IgG fraction, PBS; no preservatives or carrier proteins)
IH Human immunogen = aa residue 32-40 of Amyloid-β 1-40 peptide, conj. to KLH specific for the C-terminus of Aβ 40; reacts extremely well with the 40 isoform; no cross reaction with Aβ 42 or with APP Discontinued
Amyloid-β, APP, APLP, AICD From manufacturers (1)
BioLegend monoclonal
IgG2b
Mouse
(biotinylated IgG, PBS, no preservatives or carrier proteins)
ELISA, IH, IP, WB Human, Mouse the epitope lies within amino acids 18-22 of beta amyloid (VFFAE) reactive to aa 17-24 Aβ and to APP -
Apolipoproteins From manufacturers (1)
None polyclonal
IgG1
Rabbit
(liquid, affinity purified PBS, no preservative or carrier)
ELISA, WB Human immunogen = synthetic peptide spanning the polymorphic aa position 158 of Apo E Apo-J Discontinued
Astrocyte Markers From manufacturers (1)
None polyclonal
IgG
Rabbit
(liquid, whole sera)
IH, WB Human immunogen = synthetic peptide derived from sequence in the C-terminal region of human GFAP delta GFAP delta Discontinued
DJ-1 From manufacturers (1)
BioLegend monoclonal
IgM
Mouse
(Purified, PBS, no carrier or preservative)
ELISA, WB Human, Zebra fish - recognises a fusion protein of GST/DJ-1 but not GST alone; also recognises a FLAG-tagged DJ-1 expressed in eukaryotic cells Available from BioLegend
Mitochondrial Proteins From manufacturers (1)
BioLegend monoclonal
IgG1Λ
Mouse
(precipitated and dialyzed supernate, PBS, azide, no BSA)
DB, ELISA, IC, IF, IH, WB Human immunogen = recombinant, full-length human ERAB protein (GST fused) endogenous ERAB in extracts from cells, esp. mitochondria; virtually no crossreactivity to other human proteins Available from BioLegend
Posttranslational Modifications From manufacturers (1)
- monoclonal
IgM
Mouse
(liquid, ascites)
ELISA, IP, WB Chicken immunogen = a synthetic peptide containing Serine-O-GlcNAc detects O-GlcNAc (ß-O-linked N- acetylglucosamine) and Thr-O-GlcNAc but shows no cross reactivity with peptide determinants or other closely-related carbohydrate antigens Discontinued
Tau From manufacturers (8)
Autogen Bioclear monoclonal
IgG1
Mouse
(liquid, sterile filtered, PBS, no preservative)
ELISA, IH, WB Human immunogen = human PHF tau, aa. around phosphorylated Thr 212 and Ser 214 tau phospho. at Thr 212 and Ser 214; no cross with normal tau -
- monoclonal
IgG1
Mouse
(liquid, sterile filtered, PBS, no preservative)
ELISA, IH, WB Human immunogen = human PHF tau, aa. around phosphorylated Thr 212 and Ser 214 tau phospho. at Thr 212 and Ser 214; no cross with normal tau -
Autogen Bioclear monoclonal
IgG1
Mouse
(liquid, sterile filtered, PBS, no preservative, biotin)
ELISA, IH, WB Human immunogen = human PHF tau, aa. around phosphorylated Thr 212 and Ser 214 tau phospho. at Thr 212 and Ser 214; no cross with normal tau -
Pierce Thermo Scientific monoclonal
IgG1κ
Mouse
(biotin, no carrier or preservative)
ELISA, IH Human around phosphorylated Thr212 and Ser214 PHF tau with phosphorylated Thr212 and Ser214, not normal tau, or biopsy, autopsy or fetal tau. -
Pierce Thermo Scientific monoclonal
IgG1κ
Mouse
(purified, no carrier or preservative)
ELISA, IH, WB Human immunogen = tau around phosphorylated Thr212 and Ser214 PHF tau with phosphorylated Thr212 and Ser214, not normal tau, or biopsy, autopsy or fetal tau. -
None monoclonal
IgG1
Mouse
(liquid, semipurified Ig, serum-free , DMEM, thimerosal)
IF, IH, WB Human immunogen = Alzheimer tau isolated from AD brain (minimal epitope aa 321-391) recognizes Alzheimer tau, shows no cross-reactivity with MAPs or tubulin. Does not react with tau from age- matched control brains or with six recomb. tau isoforms -
- monoclonal
IgG1κ
Mouse
(liquid, PBS, sterile filtered, affinity purified)
ELISA, IH, WB Human partially purified human tau, aa. around phosphorylated Serine 202 Recognizes phosphorylated paired helical filament tau. Recognises tau protein phosphorylated at both serine 202 and threonine 205. No cross-reactivity with unphoshorylated tau. -
Pierce Thermo Scientific monoclonal
IgG1κ
Mouse
(serum-free supernatant, affinity purified, no carrier or preservative. Also available Biotin conj, MN-1000B)
ELISA, IH, WB Bovine, Human immunogen = purified human tau, between aa 159 and 163, (PPGQK) tau and PHF tau from human and bovine brain -
Tubulin From manufacturers (9)
None monoclonal
IgG1
Mouse
(ascites)
IH, WB Bovine, Mouse, Rat immunogen = Sarkosyl- resistant filaments from sea urchin sperm axonemes all α-tubulin isoforms Discontinued
None monoclonal
IgG1
Mouse
(ascites)
IH, WB Bovine, Mouse, Rat immunogen = Sarkosyl- resistant filaments from sea urchin sperm axonemes 50 kDa β-tubulin Discontinued
BioLegend monoclonal
IgG3
Mouse
(purified)
WB Mammal (various) immunogen = synthetic peptide C E E E E G E D E A found at the C-terminus of β II tubulin (50 kDa) Class II β-tubulin Available from BioLegend
BioLegend monoclonal
IgG3
Mouse
(purified)
WB Mammal (various) immunogen = synthetic peptide C E E E E G E D E A found at the C-terminus of β II tubulin (50 kDa) Class II β-tubulin Available from BioLegend
None monoclonal
IgG2a
Mouse
(liquid, PBS, thimerosol, protein G purified)
IF, WB Mammal (various) immunogen = peptide sequence C G E E E G E recognizes detyrosinated α-tubulin, a post translational modification of α-tubulin Discontinued
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, thimerosal, purified)
IH, WB Bovine, Chinese hamster, Rat, Sea Urchin, Chlamydomonas immunogen = taxol-assembled microtubules β-tubulin Available from BioLegend
BioLegend monoclonal
IgG2a
Mouse
(liquid, purified)
IF, WB Mammal (various) immunogen = rat brain tubulin α-tubulin, all isotypes Available from BioLegend
None monoclonal
IgG1
Mouse
(supernatant, PBS, BSA, azide)
IH Human epitope: E S E S Q G P K of β-III isoform of tubulin reacts with a neuron specific epitope (E S E S Q G P K) of the ß-III isoform of tubulin Discontinued
None monoclonal
IgG2a
Mouse
(liquid, PBS, thimerosal, protein A purified)
WB Mammal (various) immunogen = peptide sequence C G E E E G E detyrosinated α- Tubulin Discontinued
α-, β-, γ-secretase From manufacturers (1)
None monoclonal
Ig
Guinea Pig
(crude antiserum)
IH, IP, WB Human, Mouse, Rat immunogen = a peptide sequence C L R Q Q H D D F A D D I S L L K , the C-terminal 17 aa of human BACE1 recognises the mature and immature forms of BACE Discontinued
γ-secretase/ Presenilins From manufacturers (2)
None polyclonal
Rabbit
(liquid, BSA, glycerol, azide, affinity purified)
IH, WB Human immunogen = human Aph-1b/loop region and recognizes the sequence C K L L K K A S E G L K S I N P G E T A P S M R Aph-1b/loop region Discontinued
BioLegend polyclonal
Rabbit
(liquid, affinity purified)
IH, WB Human immunogen = human Aph-1aL/ C-terminal region sequence C R R Q E D S R V M V Y S A L R I P P E D Aph-1aL Available from BioLegend