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Antibodies

29333 Results

Name Source Clonality &
Isotype
Host &
Formulation
Method Reactivity Immunogen/
Epitope
Specificity Availability
APP, APLP, AICD From manufacturers (2)
BioLegend monoclonal
IgG1
Mouse
(purified, PBS, no preservatives or carrier proteins)
ELISA, IH, WB Human, Mouse Epitope lies within amino acids 573-596 of amyloid precursor protein reactive to aa 17-24 Aβ and to APP Available from BioLegend
BioLegend polyclonal
Rabbit
(liquid, no preservatives, or carriers, affinity purified)
ELISA - - specific for AICD (APP intracellular domain), a peptide fragment that results from the cleavage of C83 or C99 at the epsilon site. No reaction with the C57 or C59 γ-secretase cleavage products of APP. Available from BioLegend
Acetylcholine Receptor & Related From manufacturers (1)
BioLegend monoclonal
IgG1κ
Mouse
(liquid, raw ascites)
IF, IP, WB Human, Rat, Chicken immunogen = purified rat and chicken brain α7 neuronal nicotinic acetylcholine receptors cytoplasmic surface of chicken α7 AChRs between amino acids 380-400; binds to both native and denatured chicken α7 and denatured rat and human α7 Available from BioLegend
Amyloid-β From manufacturers (31)
BioLegend monoclonal
IgG2b
Mouse
(liquid, PBS, no preservatives or carrier proteins, HRP conj.)
ELISA, IH, WB Human, Mouse epitope lies within amino acids 18-22 of the beta amyloid peptide (VFFAE) reactive to aa 17-24 Aβ and to APPs Available from BioLegend
BioLegend polyclonal
Rabbit
(liquid, PBS, no carrier protein or preservative, affinity purified)
ELISA, IH, WB - imunogen = using beta amyloid peptide (amino acids 1-16) conjugated to KLH reacts with all isoforms of beta amyloid Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, protein-A purified, PBS, no preservative or carrier proteins, AlexaFluor® labeled)
ELISA, IH Human the epitope lies within amino acids 4-9 of beta amyloid (FRHDSG) reactive to aa 1-17 Aβ reacts to the abnormally processed isoforms, as well as precursor forms Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, no preservatives or carrier proteins, purified)
ELISA, IH, WB Human epitope lies within amino acids 1-8 of the β-Amyloid protein reacts to N-terminal aa 1-8 of β-Amyloid peptide and β-amyloid form of APP Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, no preservative or carrier protein, affinity G purified)
ELISA, IB, IH, WB Human, Mouse - reactive to the C-terminus of beta amyloid and specific for the isoform ending at the 40th amino acid Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, no preservative or carrier proteins, protein A purified, biotinylated)
IH Human, Mouse - reactive to C-terminus of Amyloid β and specific for the isoform ending at the 40th amino acid -
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, no preservatives or carrier proteins, purified, conj. HRP)
IH Human - reactive to the C-terminus of beta amyloid and specific for the isoform ending at the 40th amino acid -
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, no preservative or carrier proteins, protein G purified IgG)
ELISA, IH, WB Human, Mouse - reactive to C-terminus of Amyloid β and specific for the isoform ending at the 42nd amino acid Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, biotin labelled)
ELISA, IH, WB Human, Mouse - reactive to C-terminus of Amyloid β and specific for the isoform ending at the 42nd amino acid Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, no preservative or carrier proteins, HRP conj.)
- Human, Mouse - reactive to C-terminus of Amyloid β and specific for the isoform ending at the 42nd aa Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS no preservative or carrier proteins, IgG frac., protein A purified)
ELISA, IH, WB Human, Mouse - reactive to C-terminus of Amyloid β and specific for the isoform ending at the 43rd amino acid Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, no preservative or carrier protein, biotin conj.)
ELISA, IB, IH, IP, WB Human, Mouse epitope = lies within amino acids aa3-8 of beta amyloid (E F R H D S) reactive to the C-terminus of beta amyloid and specific for the isoform ending at the 43rd amino acid Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, purified)
ELISA, IH, IP, WB Rodent (various) - recognizes sequence of Aβ, β-CTF, sAPP-α, and full length APP; negligible cross reactivity with human isoforms of APP and beta amyloid. Available from BioLegend
BioLegend polyclonal
Rabbit
(liquid, PBS, no carrier protein or preservative, affinity purified)
ELISA, IH, WB Rodent (various) imunogen = rodent amyloid-β peptide conj. to KLH recognizes beta amyloid, all isoforms Available from BioLegend
BioLegend polyclonal
Rabbit
(liquid, PBS, glycerol, no carrier protein or preservative, boitin labeled)
ELISA, IH, WB Rodent (various) - all isoforms of rhodent Aβ Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS; no preservatives or carrier proteins)
ELISA, IH, WB - epitope lies within amino acids 1-10 of beta amyloid amyloid β Available from BioLegend
BioLegend monoclonal
IgG1
Rabbit
(liquid, PBS, no carrier protein or preservative, affinity purified)
ELISA, IB, WB Human, Rodent (various) imunogen = beta amyloid peptide (aa1-16) conj. to KLH reactive to the C-terminus of beta amyloid and specific for the isoform that ends at the 40th amino acid Available from BioLegend
BioLegend polyclonal
Rabbit
(liquid, PBS, IgG fraction, no preservative or carrier protein)
IH Rodent (various) immunogen = rodent amyloid-β peptide rodent Amyloid-β ,all isoforms Available from BioLegend
None monoclonal
IgG1
Mouse
(liquid, PBS, no preservatives or carrier proteins, purified, HRP conj.)
ELISA, IH, WB Human epitope = lies within aa 3-8 of the β-amyloid peptide (EFRHDS) reactive to aa 1-16 of β-Amyloid (precursor forms as well as abnormally processed isoforms Discontinued
None monoclonal
IgG1
Mouse
(liquid, purified F(ab')2 frag of clone 6E10 monoclonal ab, PBS, no preservatives or carrier proteins)
ELISA, IH, WB Human epitope = lies within aa 3-8 of β-amyloid peptide (EFRHDS) reactive to aa 1-16 of β-amyloid peptide (precursor forms and abnormally processed isoforms) Discontinued
None monoclonal
IgG1
Mouse
(liquid, PBS; no preservatives or carrier proteins)
ELISA, IH, IP, WB Human epitope lies within amino acids 3-8 of the beta Amyloid peptide (E F R H D S) reactive to amino acid residue 1-16 of beta amyloid.; reacts to the abnormally processed isoforms, as well as precursor forms Discontinued
None monoclonal
Rabbit
(liquid, PBS, no carrier protein or preservative, purified)
ELISA - - reactive to the C-terminus of beta amyloid and specific for the isoform that ends at the 42nd amino acid. Discontinued
None polyclonal
IgG1
Rabbit
(liquid, PBS, glycerol, no preservative or carrier protein, affinity G purified, conj. biotin)
IB, IH, WB Human, Mouse immunogen = peptide conj. to KLH. specific for the C-terminus of Aβ 42; reacts extremely well with the 42 isoform; no cross-reaction with Aβ 40 or APP Discontinued
None polyclonal
IgG1
Rabbit
(liquid, PBS, no preservative or carrier protein, affinity G purified)
IB, IH, WB Human, Mouse immunogen = peptide conj. to KLH. specific for the C-terminus of Aβ 42; reacts extremely well with the 42 isoform; no cross-reaction with Aβ 40 or APP Discontinued
None polyclonal
IgG1
Rabbit
(liquid, PBS, glycerol, no preservative or carrier protein, conj. biotin)
IH Human, Mouse immunogen = peptide conj. to KLH. specific for the C-terminus of Aβ 42; reacts extremely well with the 42 isoform; no cross-reaction with Aβ 40 or APP Discontinued
None polyclonal
IgG
Rabbit
(purified, IgG fraction, PBS, no preservatives or carrier proteins)
IH Human, Mouse immunogen = amyloid β 1-42 peptide, conj. to KLH specific for the C-terminus of Aβ 1-42; no cross reaction with Aβ 1-40 or APP Discontinued
None polyclonal
Rabbit
(liquid, PBS, glycerol, no preservative or carrier proteins, affinity purified, bintinylated)
ELISA, IH, WB Human, Mouse immunogen = amyloid-β conj. to KLH specific for C-terminus of Aβ40 isoform; no cross-reaction with Aβ42 or APP Discontinued
None polyclonal
Rabbit
(liquid, PBS, glycerol, no preservative or carrier proteins, IgG frac., biotinylated)
IH Human immunogen = amyloid-β peptide conj. to KLH specific for C-terminus of Aβ 40 isoforms; no cross-reaction with Aβ 42 or APP Discontinued
None polyclonal
Rabbit
(liquid, PBS, no preservative or carrier proteins, affinity purified)
ELISA, IH, WB Human immunogen = amyloid-β conj. to KLH specific for C-terminus of Aβ 40 isoform; no cross-reaction with Aβ42 or APP Discontinued
None monoclonal
IgG1
Mouse
(liquid, purified, no preservative or carrier proteins)
ELISA, IH, WB Human epitope lies within amino acids 1-8 of the β-Amyloid peptide reacts to N-terminal aa 1-8 of β-amyloid peptide (precursor forms and abnormally processed isoforms) and β-amyloid form of APP Discontinued
None kit
Unknown Host
(Chemiluminescent sandwich ELISA Kit: Capture Antibody Coated Plate; HRP Detection Antibody, chemiluminescent substrate)
ELISA Human - specific for the 1-42 isoform of beta amyloid; has negligible cross reactivity with the 1-40 isoform of beta amyloid Discontinued
Apolipoproteins From manufacturers (4)
BioLegend monoclonal
IgG1
Mouse
(liquid, supernatant, PBS, azide)
ELISA, IH, IP, WB Human immunogen = synthetic peptide spanning the polymorphic aa position 158 of Apo E E2, E3 and E4 isoforms of Apo-E Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, ascites PBS, protein A purified)
ELISA, IH, IP, WB Human immunogen = synthetic peptide spanning the polymorphic aa position 158 of Apo E E2, E3 and E4 isoforms of Apo-E Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, no preservative, purified)
ELISA, WB Human - E4 isoforms of Apo-E Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, no preservative, protein A purified)
ELISA, WB Human - E4 isoforms of Apo-E Available from BioLegend
Astrocyte Markers From manufacturers (1)
BioLegend monoclonal
IgG1, κ
Mouse
(supernatant)
IF, IH, WB Mammal (various), Cow, Pig, Human, Mouse, Rat, Avian (various) immunogen = purified pig spinal cord GFAP recognizes 55 kDa band; useful as marker of normal and reactive astrocytic cells and neural stem cells Available from BioLegend
Aβ Degrading Enzymes, CD_ except CD11b, CD40, CD45 and CD147 From manufacturers (5)
None monoclonal
IgG1
Mouse
(liquid, PBS, azide, affinity purified)
FC, IH, IP, WB Human Immunogen = Pre-B cell line NALM-6 CD10 (CALLA) Discontinued
None monoclonal
IgG1
Mouse
(liquid, PBS, BSA, azide, affinity purified; conj. to PE)
FC Human immunogen = Pre-B cell line NALM-6 CD10 (CALLA) Discontinued
None monoclonal
IgG1
Mouse
(liquid, PBS, BSA, azide, affinity purified; conj. to PE/Cy5)
FC Human Immunogen = Pre-B cell line NALM-6 CD10 (CALLA) Discontinued
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, azide, affinity purified)
FC Baboon, Chimpanzee, Human, Cynomolgus, Rhesus - CD10 (CALLA) Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, BSA, azide, affinity purified, conj. to PE/Cy5)
FC Baboon, Chimpanzee, Human, Cynomolgus, Rhesus - CD10 (CALLA) Available from BioLegend
CD_ except CD11b, CD40, CD45 and CD147 From manufacturers (10)
None monoclonal
IgG2a, κ
Mouse
(liquid, PBS, azide, affinity purified, biotinylated)
FC, IC Bovine, Human, Cynomolgus, Rat immunogen = Burkittt's lymphoma cell line Raji CD54 discontinued
None monoclonal
IgG2a, κ
Mouse
(liquid, PBS, azide, affinity purified, PE)
FC, IC Bovine, Human, Cynomolgus, Rat immunogen = Burkittt's lymphoma cell line Raji CD54 discontinued
None monoclonal
IgG2a, κ
Mouse
(liquid, PBS, azide, affinity purified, FITC)
FC, IC Bovine, Human, Cynomolgus, Rat immunogen = Burkittt's lymphoma cell line Raji CD54 discontinued
None monoclonal
IgG2a, κ
Mouse
(liquid, PBS, azide, affinity purified)
FC, IC, IF, IH, IP, WB Bovine, Human, Cynomolgus, Rat immunogen = Burkittt's lymphoma cell line Raji CD54 discontinued
None monoclonal
IgG1, κ
Mouse
(liquid, PBS, azide, affinity purified, conj. Biotin)
FC, IP, WB Human immunogen = T cell line HPB-ALL CD63 discontinued
None monoclonal
IgG1, κ
Mouse
(liquid, PBS, BSA, azide, affinity purified, conj. PE)
FC Human immunogen = T cell line HPB-ALL CD63 discontinued
None monoclonal
IgG1, κ
Mouse
(liquid, PBS, BSA, azide, affinity purified, conj. FITC)
FC Human immunogen = T cell line HPB-ALL CD63 discontinued
BioLegend monoclonal
IgG1, κ
Mouse
(liquid, PBS, azide, affinity purified)
FC, IP, WB Human immunogen = T cell line HPB-ALL CD63 discontinued
BioLegend monoclonal
IgG
Hamster
(liquid, PBS, azide, affinity purified)
FC, IP, WB Mouse immunogen = soluble recomb. mouse IFN-γR α chain protein CD119 ( IFN-γRα) Available from BioLegend
BioLegend monoclonal
IgG1, κ
Mouse
(liquid, PBS, azide, affinity purified)
FC Human immunogen = NIH 3T3 cells transfected with human PDGFRalpha CD140a (PDGFRα) Available from BioLegend
CD_ except CD11b, CD40, CD45 and CD147, Cytokines & Receptors From manufacturers (2)
None monoclonal
IgG1, κ
Mouse
(liquid, PBS, azide, affinity purified)
FC, IH, IP, WB Human immunogen = human IFN-γRα, purified from human placenta CD119 ( IFN-γRα) Discontinued
None monoclonal
IgG2b, κ
Mouse
(liquid, PBS, azide, affinity purified)
FC, IF, IP Human immunogen = Human IFN-γRα, purified from human placenta CD119 ( IFN-γRα) Discontinued
CD_ except CD11b, CD40, CD45 and CD147, Growth Factors From manufacturers (3)
BioLegend monoclonal
IgG1, κ
Mouse
(liquid, PBS, BSA, azide, affinity purified)
FC Human immunogen = NIH-3T3 cells transfected with human PDGFRbeta CD140b (PDGFRβ) Available from BioLegend
BioLegend monoclonal
IgG1, κ
Mouse
(liquid, PBS, azide, affinity purified, biotin conjugated)
FC Human immunogen = NIH-3T3 cells transfected with human PDGFRbeta CD140b (PDGFRβ) Available through BioLegend
BioLegend monoclonal
IgG1, κ
Mouse
(liquid, PBS, BSA, azide, affinity purified, APC conjugated)
FC Human immunogen = NIH-3T3 cells transfected with human PDGFRbeta CD140b (PDGFRβ) Available from BioLegend
Calcium related From manufacturers (1)
BioLegend polyclonal
Rabbit
(liquid, NaCl, azide)
IC, IH, WB Cow, Cat, Dog, Horse, Mouse, Rat Immunogen = purified recombinant human S100A4 monomer expressed by E. coli S-100A4 Available from BioLegend
Glutamate Receptor & Related From manufacturers (1)
BioLegend polyclonal
Rabbit
(liquid, Hepes, NaCl, BSA, glycerol, affinity purified)
ELISA, IH, IP, WB Rat Immunogen = synthetic phosphopeptide corresponding to aa residues surrounding the phospho-Ser845 of rat GluR1 GluR1 phosphorylated at Ser 845 (100 kDa) Available from BioLegend
Immune Cells From manufacturers (5)
BioLegend monoclonal
IgG2a
Mouse
(liquid, affinity purified, PBS, azide, biotin conj.)
Block, FC, IF, IH Human, Rhesus, Guinea Pig immunogen = Ba/F3 cell line expressing human TLR4 TLR4 Available from BioLegend
BioLegend monoclonal
IgG2a
Mouse
(liquid, affinity purified, PBS, azide)
Block, FC, IF, IH Human, Rhesus, Guinea Pig immunogen = Ba/F3 cell line expressing human TLR4 TLR4 Available from BioLegend
BioLegend monoclonal
IgG2a
Mouse
(liquid, affinity purified, PBS, azide)
Block, FC, IF, IH, IP, IS, WB Bovine, Cat, Baboon, Chimpanzee, Human, Cynomolgus, Rhesus - detects human HLA-A,B,C Available from BioLegend
BioLegend monoclonal
IgG2a
Mouse
(liquid, affinity purified, PBS, azide)
Block, FC, IF, IH, IP, IS, WB Human immunogen = Human TLR2-transfected CHO cells TLR2 Available from BioLegend
None monoclonal
IgG2a
Mouse
(liquid, affinity purified, PBS, azide, Biotin conj.)
Block, FC, IF, IH, IP, IS, WB Human immunogen = Human TLR2-transfected CHO cells TLR2 discontinued
MAPs From manufacturers (2)
None monoclonal
IgG1
Mouse
(ascities fluid, azide)
ELISA, IH, WB Mammal (various), Xenopus - Reacts with MAP2a, MAP2b and possibly MAP2c Discontinued
None monoclonal
IgG1
Mouse
(high titer ascites fluid)
IC, IH, WB Mammal (various), Frog - MAP-2a and b in neuronal cell bodies and dendrites in tissue sections and cell cultures Discontinued
Mitochondrial Proteins From manufacturers (1)
None monoclonal
IgG2bκ
Mouse
(precipitated and dialyzed supernate, PBS, azide, no BSA)
DB, ELISA, IH, WB Human immunogen = recombinant, full-length human ERAB protein (GST fused); epitope is aa 61-67 human ERAB protein (27 kDa), virtually no crossreactivity to other human proteins Discontinued
Neurofilaments From manufacturers (12)
BioLegend monoclonal
IgM
Mouse
(ascites, concentrate)
ELISA, IC, IH, WB Mammal (various) non phos- phorylated epitope in neurofilament H neuronal cell bodies, dendrites and a some thick axonsin the central and peripheral nervous systems Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, ascites, azide)
ELISA, IC, IH, WB Mammal (various) non phosphory- lated epitope accessible in neurofilamentH wide distribution of neuronal cell bodies, dendritesand some thick axons in the central and peripheral nervous systems Available from BioLegend
BioLegend monoclonal
IgM
Mouse
(liquid, ascites, concentrate)
ELISA, IC, IH, WB Mammal (various) non phos- phorylated epitope accessible in neurofilament H some neuronal cell bodies, dendrites and very few thickaxons in the central and peripheral nervous systems; some neuronal cellbodies are intensely stained but few neuronal cell processes react Available from BioLegend
None monoclonal
IgG1
Mouse
(ascites, concentrate)
IC, IH, WB Mammal (various) phosphorylated epitope in neurofilament H thick and thin axons and faintly stains some cell bodies;unlike the other antibodies to phosphorylated neurofilament epitopes, doesnot react with aluminum tangles Discontinued
None monoclonal
IgG1
Mouse
(ascites, concentrate)
IC, IH, WB Mammal (various), Chicken, Frog band extending from the phosphorylated neurofilamentposition at 200kD, pI 5.1, toward the non phosphorylated position at 170kD,pI 6.2 neurofilaments of high and low degrees of phosphorylationfrequently detects early changes in neuronal cell body staining Discontinued
None monoclonal
IgG1
Mouse
(ascites, concentrate)
IC, IH, WB Mammal (various), Chicken phosphorylated epitope in extensively phosphorylatedneurofilament H axonal antibody, also detecting intraneuronal Alzheimertangles; nerve cell bodies are generally unreactive Discontinued
None monoclonal
IgM
Mouse
(ascites, concentrate)
IC, IH, WB Mammal (various) non phos- phorylated epitope accessible in both phosphorylatedand non phosphorylated neurofilament H and, to a lesser extent, in neurofilamentM neuronal cell bodies, dendrites and some thick axonsin the central and peripheral nervous systems; reaction with isolated neurofilamentsis not intensified by dephos- phorylation Discontinued
None monoclonal
IgG1
Mouse
(liqiud, ascites, concentrate)
IC, IH, WB Mammal (various) non phos- phorylated epitope neurofilament H neuronal cell bodies, dendrites and some thick axonsin the central and peripheral nervous systems, but not thin axons;reflects extent of aberrant phosphorylation of neurofilaments in Alzheimer'sdisease. SMI 32 visualizes two bands (200 and 180 kDa) which merge into a single NFH line on two-dimensional blots Discontinued
None monoclonal
IgG1
Mouse
(liquid, ascites, concentrate)
ELISA, IC, IH, WB Mammal (various), Chicken, Frog phosphorylated epitope in extensively phosphorylated neurofilament H phosphorylated neurofilament H and, to a lesser extent, neurofilament M is detected in most mammalian species, in thick and thin axons but not cell bodies Discontinued
None monoclonal
IgG1 cocktail
Mouse
(liquid, ascites, concentrate)
ELISA, IC, IH, WB Mammal (various) - visualizes axons in an area-specific maturation patternin human fetal brain; visualizes aberrantly sprouting axons in neuriticplaques derived from cortico-cortical fibers in A.D. and identifies loss of synaptic circuitry Discontinued
None monoclonal
IgG1 & IgM
Mouse
(ascites, azide, concentrate)
ELISA, IC, IH, WB Mammal (various) - Neurons with non phosphorylated neurofilaments; providesan early marker of neuronal migration and differentiation in human fetal development Discontinued
None monoclonal
IgG1
Mouse
(liquid, ascites, concentrate)
ELISA, IC, IH, WB Mammal (various) phosphorylated epitope in extensively phosphorylated neurofilament H phosphorylated neurofilament H and, to a lesser extent,neurofilament M, in axons but not dendrites. In A.D., extraneuronal (ghost)neurofibrillary tangles in frozen sections Discontinued
Oligodendrocyte Markers/Myelin From manufacturers (1)
None monoclonal
IgG1
Mouse
(liquid, ascites, high titer)
ELISA, IH, WB Bovine, Dog, Sheep, Pig, Human, Mouse, Rat - reacts with the 46 and 48 Mr subunit of the 94 Mr myelin CNPase dimer; detects developing and adult myelin, developing oligodendrocytes and Schwann cells Discontinued
Prion protein From manufacturers (6)
BioLegend monoclonal
IgG2A
Mouse
(liquid, purified, PBS, biotin conj.)
ELISA, IH, IP, WB Cat, Human, Hamster epitope lies within amino acids 109-112 of prion protein 3F4 is reactive to amino acid residues 109-112 of prion protein (PrP) from humans, hamsters, and felines. It recognizes both protease sensitive and protease resistant forms of PrP (after denaturing) Available from BioLegend
BioLegend monoclonal
IgG2A
Mouse
(liquid, purified, PBS,)
ELISA, IH, IP, WB Cat, Human, Hamster epitope lies within amino acids 109-112 of prion protein 3F4 is reactive to amino acid residues 109-112 of prion protein (PrP) from humans, hamsters, and felines. It recognizes both protease sensitive and protease resistant forms of PrP (after denaturing) Available through BioLegend
BioLegend monoclonal
IgG2A
Mouse
(liquid, ascites)
ELISA, IH, IP, WB Cat, Human, Hamster epitope lies within amino acids 109-112 of prion protein 3F4 is reactive to amino acid residues 109-112 of prion protein (PrP) from humans, hamsters, and felines. It recognizes both protease sensitive and protease resistant forms of PrP (after denaturing) Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(supernatant, purified, PBS, no preservatives or carrier proteins)
ELISA, IH, WB Bovine, Sheep, Mouse Immunogin within recombinant mouse PrP protein, aa 23-237 7D9 reacts exceptionally well with bovine, sheep, and mouse PrP. It is 10 fold less reactive to feline, hamster, and human PrP. 7D9 recognizes both protease sensitive and protease resistant forms of PrP Available from BioLegend
BioLegend monoclonal
IgG2A
Mouse
(liquid, affinity purified, PBS, no preservatives or carrier proteins)
ELISA, IB, IH Deer, Elk, Bovine, Mule, Sheep, Human, Hamster, Mouse The epitope falls within amino acids 93-109 of PrP 6D11 reacts with both the PrPc and PrPsc forms Available from BioLegend
None monoclonal
IgG1
Mouse
(supernatant, purified, PBS, no preservatives or carrier proteins)
ELISA, IF, IH, WB Cat, Sheep, Rabbit The epitope site appears to be non-linear (discontinuous). This antibody recognizes both the cellular (protease sensitive) and infectious (protease resistant) isoforms of PrP Discontinued
Protein Trafficking From manufacturers (1)
BioLegend monoclonal
IgG2b
Mouse
(liquid, serum, PBS, thimerosal)
IF, IP, WB Mammal (various), Yeast Immunogen = peptide derived from bovine clathrin light chain corresp. to the conserved region of the light chains; residues 23-44 Clathrin light chain a and b variants (CLC) Available from BioLegend
Synaptic Vesicle Fusion From manufacturers (1)
None monoclonal
IgG1
Mouse
(ascites fluid, azide)
ELISA, IC, IH, WB Various animal immunogen = whole, unaltered SNAP-25 (epitope lies in the amino end of the C-terminal of SNAP-25) detects SNAP 25; visualizes synapse-rich areas of brain and retina in a wide variety of mammalian and non-mammalian species Discontinued
Synucleins From manufacturers (5)
BioLegend monoclonal
IgG2a
Mouse
(raw ascites fluid)
IH, IP, WB Zebra, Human, Mouse, Rat, Fish (various) immunogen = recombinant alpha and beta synuclein α- and β-synuclein, residues 130-140 Available from BioLegend
None monoclonal
IgG1
Mouse
(frozen, supernatant, no preservative)
DB, IH, WB Human immunogen = purified human α-synuclein produced in E. coli α-synuclein; no cross with β- and γ-synuclein Discontinued
None monoclonal
IgG1
Mouse
(liquid, PBS, no preservative, protein G purified)
DB, ELISA, IH, WB Human immunogen = synthetic peptide corresp. to aa 115-122 of human α-synuclein α-synuclein Discontinued
None monoclonal
IgG1
Mouse
(frozen, PBS, no preservative)
IH, WB Human, Mouse, Rat immunogen = purified human α-synuclein produced in E. coli α-synuclein; no cross reaction with β or γ-synuclein Discontinued
None monoclonal
IgG1
Mouse
(purified antibody, PBS; no preservatives or carrier proteins)
DB, IH, WB Human - LB509 recognizes amino acids 115-122 of human α-synuclein Discontinued
Tau From manufacturers (1)
BioLegend monoclonal
IgG1
Mouse
(high titer, ascites)
IH, WB Bovine, Rat (aa 95 to 108 sequence of tau in a conformation partially dependent on serine in position 101) strongly with PHF Tau in Alzheimer disease; weakly with normal tau Discontinued
Tools From manufacturers (1)
BioLegend monoclonal
IgG1
Mouse
(purified)
FC, IC, IF, IP, WB Non-specific immunogen = affinity purified cre recombinase reacts with Cre Recombinase; is highly specific for a 34 bp DNA sequence (loxP) found in P1 DNA. It can be used to determine the success of gene manipulations in transgenic animals Available from BioLegend
Tubulin From manufacturers (1)
BioLegend polyclonal
Rabbit
(affinity purified, PBS, thimerosal, glycerol)
IF, IH, WB Mammal (various) immunogen = microtubules derived from rat brain; same epitope as clone TUJ1 reactive to neuron specific Beta-tubulin (Beta III), not Beta-tubulin found in glial cells. Available from BioLegend
γ-secretase/ Presenilins From manufacturers (2)
None polyclonal
Rabbit
(serum, concentrated, no preservative)
IP, WB Human immunogen = peptide (T E L P A P L S Y F N R K C) conj. to KLH presenilin 1 Discontinued
None polyclonal
IgG
Rabbit
(liquid, purified, PBS, no carrier, no preservative)
IP, WB Human immunogen = aa 698-709 of nicastrin nicastrin protein Discontinued