Antibody

PSA-NCAM (2-2B)

Clonality: monoclonal
Host: Mouse
Isotype: IgM
Methods: IC, IH, RIA, WB
Source: Chemicon and Upstate are Millipore
cat# MAB5324
References:
He, 2009
Chumley, 2007
Formulation: liquid, ascites, glycerol, no preservative
Reactivity:
Reacts in: Human, Mouse, Rat

Immunogen/Epitope

Immunogen = Viable Meningococcus group B (strain 355)

Specificity

Reacts with alpha 2-8 linked neuraminic acid (NeuAc-alpha 2-8) n with n >10 (this polymer is usually termed polysialic acid --PSA). Works well on all species expressing PSA-NCAM

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References

Paper Citations

  1. . Interruption of beta-catenin signaling reduces neurogenesis in Alzheimer's disease. J Neurosci. 2009 May 20;29(20):6545-57. PubMed.
  2. . EphB receptors regulate stem/progenitor cell proliferation, migration, and polarity during hippocampal neurogenesis. J Neurosci. 2007 Dec 5;27(49):13481-90. PubMed.

Further Reading

No Available Further Reading