Antibody

PS-1 NTF

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Clonality: polyclonal
Host: Unknown Host
Source: AB14
(Sam Gandy,
Mount Sinai Alzheimer's Disease Research Center, NYC)
References:
Liu, Y, 2009
Sato, 2007
Luo, 2003
Esler, 2002
Lazarov, 2006
Reactivity:
reference: Xu H, Gouras G K, ... Greengard P, and Gandy S. <em>Nat. Med.</em> 4,447-451, 1998

Immunogen/Epitope

 

Specificity

 

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References

Paper Citations

  1. . Intracellular trafficking of presenilin 1 is regulated by beta-amyloid precursor protein and phospholipase D1. J Biol Chem. 2009 May 1;284(18):12145-52. PubMed.
  2. . Active gamma-secretase complexes contain only one of each component. J Biol Chem. 2007 Nov 23;282(47):33985-93. PubMed.
  3. . PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1. J Biol Chem. 2003 Mar 7;278(10):7850-4. Epub 2003 Jan 8 PubMed.
  4. . Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2720-5. PubMed.
  5. . Electron microscopic structure of purified, active gamma-secretase reveals an aqueous intramembrane chamber and two pores. Proc Natl Acad Sci U S A. 2006 May 2;103(18):6889-94. PubMed.

External Citations

  1. Sam Gandy

Further Reading

No Available Further Reading