Antibody

PS-1 NTF

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Clonality: polyclonal
Host: Rabbit
Source: antibodies 95/23 and 98/1
(Janetta Culvenor,
Department of Pathology, The University of Melbourne, Victoria, Australia)
used in paper by Runz, 2002

Immunogen/Epitope

epitope at PS1, aa 1-20

Specificity

PS1 in human neuroblastoma SH-SY5Y wild type and PS1 transfectants (SY5Y-PS1) as well as in mouse P19, in CHO-K1 and CHO-APP770 transfected cells, in rat cerebellar granule and hippocampal neurons, and astrocytes. 50 kDa and 30 kDa presumptive cleavage product in WB

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References

Paper Citations

  1. Runz H, Rietdorf J, Tomic I, de Bernard M, Beyreuther K, Pepperkok R, Hartmann T. Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells. J Neurosci. 2002 Mar 1;22(5):1679-89. PubMed.

External Citations

  1. Janetta Culvenor
  2. Department of Pathology, The University of Melbourne, Victoria, Australia

Further Reading

No Available Further Reading