Methods: ELISA, IH, WB
Source: Cat# 01-010, 01-011
Formulation: liquid, serum-free medium, azide
Reacts in: Mammal (various), Human
The epitope falls within amino acids 144-152, (DYEDRYYRE) of human prion protein
mAB 6H4 recognizes the sequence DYEDRYYRE in the prion protein; reacts on Western blots with mouse and hamster PrP, indicating that the substitution at position 145 does not prevent binding of 6H4
- Parkin ET, Watt NT, Hussain I, Eckman EA, Eckman CB, Manson JC, Baybutt HN, Turner AJ, Hooper NM. Cellular prion protein regulates beta-secretase cleavage of the Alzheimer's amyloid precursor protein. Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):11062-7. PubMed.
No Available Further Reading