Antibody

Presenilin-2, C-Terminal

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Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Source: Calbiochem EMD Biosciences
Cat# PC235-1SET
discontinued or not available
Reference
(poly Presenil-2)
Lee, 2002
Formulation: affinity purified IgG, PBS, azide, gelatin
Reactivity:
Reacts in: Human, Mouse, Rat

Immunogen/Epitope

synthetic peptide (EEDSYDSFGEPS) corr. to aa 324-335 from the C-terminus of human PS2

Specificity

detects ~20 kDa proteolytic fragment of presenilin-2

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References

Paper Citations

  1. . Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch. J Biol Chem. 2002 Nov 22;277(47):45013-9. PubMed.

Further Reading

No Available Further Reading